Sepsis-induced PICS: Immunometabolic mechanisms, emerging biomarkers, and precision management
June 2026
Sepsis, a life-threatening organ dysfunction caused by infection, casts a lingering shadow over its survivors. Many develop persistent inflammation, immunosuppression, and catabolism syndrome (PICS),...
Molecular basis of graphene-induced oxidative stress and mitochondrial signaling in target cells: Consequences for therapeutic window and design of redox-responsive payloads
June 2026
Graphene nanomaterials (GNMs) have emerged as a unique class of bioactive interfaces capable of directly modulating cellular redox homeostasis and mitochondrial function through their distinctive physicochemical...
Exosome/vancomycin enable targeted therapeutics of liver abscess with enhanced anti-inflammation performance
June 2026
Current clinical management for pyogenic liver abscess primarily relies on broad-spectrum antibiotics, necessitating excessive dosing due to targeting limitations, which would lead to severe drug resistance...
GALNTs in cancer: Driving tumor progression and opening a new therapeutic frontier
June 2026
The human GALNT family consists of 20 isoenzymes that initiate mucin-type O-glycosylation. These enzymes catalyze the transfer of N-acetylgalactosamine to serine or threonine residues on protein substrates....
An analysis of research on healthy lifestyle and digestive system cancers using bibliometric methods over the last two decades
June 2026
Digestive system cancers remain major contributors to global cancer-related morbidity and mortality, and increasing evidence suggests that modifiable lifestyle factors are closely associated with their...
In situ-forming turkish galls polyphenol/CMCS hydrogel powder for the treatment of radiation-induced oral mucositis
June 2026
Radiation-induced oral mucositis (RIOM) is a debilitating complication in head and neck cancer patients undergoing radiotherapy. The severe ulcerative lesions often necessitate treatment interruptions,...
Single-cell encapsulation of Agathobacter rectalis in Aloe vera gel alleviates DSS-induced colitis by remodeling the gut microbiota-metabolite axis
June 2026
Gut microbiota dysbiosis and metabolic disturbances are implicated in inflammatory bowel disease (IBD). Current probiotic therapies are limited by poor bioavailability and inadequate colonic colonization....