Repair of DNA and protein damages caused by formaldehyde improves methanol assimilation
Available online 17 May 2025
Methanol is regarded as a next-generation feedstock. However, the efficiency of synthetic methylotrophs remains suboptimal compared to their preferred carbon sources. In this study, we conducted a comprehensive...
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Systemic delivery of stealth adenoviral vector to reinvigorate antitumor immunity by PD-L1 genome editing and TIGIT/CD155 blockade
Available online 14 May 2025
Treatment with combined immune checkpoint blockade (CICB) has been considered as an effective approach to increase the objective response rate for cancer immunotherapy, but at the cost of significantly...
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Nano-oncology revisited: Insights on precise therapeutic advances and challenges in tumor
Available online 14 May 2025
The integration of nanotechnology with cancer therapy has revolutionized traditional diagnostic and treatment methods, giving rise to the new interdisciplinary field of nano-oncology. With advancements...
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Speeding up adiabatic holonomic quantum gates via π-pulse modulation
Available online 13 May 2025
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Terahertz's Silent Revolution in Physics, Engineering, and Life Science: Beyond the Spectrum
Available online 11 May 2025
Terahertz technology is revolutionizing photonics, biomedicine, and communications by merging non-ionizing radiation with molecular sensitivity and material penetration. Advances in metamaterials, adaptive...
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Multimodal techniques based on synchrotron radiation X-rays for revealing interactions of metallic nanoparticles with biological matrices
Available online 10 May 2025
With the increasing applications of metallic nanoparticles (MNPs) in biomedicine and daily consumer products, it is crucial to explore the interactions of MNPs with biological matrices (MNPs-bio), determining...
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Advances in hydrological research in China over the past two decades: Insights from advanced large language model and topic modeling
Available online 10 May 2025
•Advanced technologies including large language model and topic modeling revealed evolving research patterns and priorities.•Hydrology research in China grew 17.8 papers/year, with increasing author...
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Interpretable machine learning models to predict cadmium in wheat for safe production and soil management
Available online 9 May 2025
Accurate prediction of cadmium (Cd) concentrations in wheat grain is essential for ensuring food safety and sustainable agriculture. Here, we developed a predictive model using nine machine learning...
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Primary cilia in growth plates orchestrate long bone development
Available online 3 May 2025
The growth plate plays a crucial role in long bone development and elongation, housing stem cells that contribute to bone formation. This study investigates the role of primary cilia, specialized organelles...
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Mathematical Foundation of the UN(1) Quantum Geometric Tensor
Available online 2 May 2025
In this paper, we systematically establish the mathematical foundation for the UN(1) quantum geometric tensor (QGT) of mixed states Explicitly, we present a description based on the UN(1) principal...
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Mild periodate oxidation-based sialic acid-targeted background-free SERS imaging in cells and tissues
Available online 30 April 2025
•Specific SERS profiling of sialic acid on cell and tissue samples.•Selective labeling of sialic acid is achieved by its mild oxidation by periodate.•The labeled Raman reporter has a background-free...
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Joint effects of sleep behaviors and physical activity on brain structure and cognitive function
Available online 29 April 2025
Sleep behaviors and physical activity (PA) are widely used to predict the risk of neurodegenerative disease. However, how sleep and PA interact to influence brain and cognitive health remains unknown....
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Cerium(III) bromide hybrid with near-unity photoluminescence quantum efficiency for high-resolution and fast x-ray imaging
Available online 29 April 2025
Trivalent lanthanide Ce(III) with a typical allowed 4f – 5d transition generally exhibits short decay time in a nanosecond level, beneficial to fast X-ray imaging applications. Herein, we rationally...
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Association between chronic respiratory diseases and the attributable risk of long-term exposure to atmospheric particulate matters among middle-aged and elderly Chinese population
Available online 29 April 2025
•This study determines the attributable risk of long-term PMs exposure to CRD.•Novel PMs estimate models have been developed to accurately assess individuals exposure.•Prolonged PM exposure is linked...
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Robust strong coupling of single quantum emitters with plasmonic nanocavity on one-dimensional photonic crystal substrate
Available online 29 April 2025
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Artificial intelligence in echocardiography: Applications and future directions
Available online 25 April 2025
Traditional ultrasound methods, particularly cardiac echocardiography, depend predominantly on evidence-based decision trees and risk-scoring systems to guide and standardise clinical decision-making....
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ENSO-induced precipitation seasonality in the Chinese Loess Plateau during 1767-2050 CE
Available online 23 April 2025
Climate change has not only altered the total amount of rainfall but also significantly impacted its seasonal distribution. This alteration is particularly critical in monsoonal regions, where the availability...
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Fabricating polarization materials with subnanowires
Available online 23 April 2025
Polarization materials have widespread and crucial applications in sensing, display and optical devices. Subnanowires (SNWs) with polymer-analogue properties and unique self-assembly characteristics...
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A Channel-Independent Transformer Approach for Ride-Hailing Demand Prediction with Internet Sentiment and Transport Capacity
Available online 22 April 2025
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Seizure type classification algorithm based on multi-dimensional brain network feature selection
Available online 21 April 2025
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Obox1 deficiency impairs fertility in female mice
Available online 19 April 2025
•Obox1 deficiency result in reduced litter size and impaired oocyte ovulation•Female mice lacking Obox1 exhibit decreased levels of gonadotropins and sex hormones•Superovulated Obox1 knockout mice display...
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Self-powered technologies for smart bearings
Available online 19 April 2025
As industrial equipment becomes increasingly complex and efficient, smart bearings play a crucial role in monitoring the operating status of mechanical devices, improving efficiency, and extending service...
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An aerogel-based light-driven knudsen pump approaching complete passive capturing of airborne particles in wide size ranges
Available online 18 April 2025
Aerosol sampling stands as an essential step in air quality monitoring and characterization. Active sampling provides accurate aerosol determination, while passive sampling offers cost-effective and...
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Electronic modulation of PtCo catalysts by topological carbon defects boosting durable oxygen reduction reaction in acidic media
Available online 14 April 2025
Pt-carbon materials are identified as state-of-the-art electrocatalysts for oxygen reduction reaction (ORR). However, it is still a big challenge to reduce the usage of Pt while maintaining the high...
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Liquid phase delamination of non-van der Waal two-dimensional sheets of tin monoxide for flexible and long lifespan sodium-ion batteries
Available online 13 April 2025
Sodium-ion batteries are attractive alternatives to Li-ion batteries, but typically suffer from slow redox kinetics and short cycle life. These problems arise mainly from the much larger radius of the...
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