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ISSN: 2667-3258
CN: 10-1722/N
p-ISSN: 2096-9457

Gefitinib facilitates PINK1/Parkin-mediated mitophagy by enhancing mitochondrial recruitment of OPTN

Gefitinib, a well-known epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor for the targeted therapy of lung cancer, induces autophagy in association with drug resistance. However, it...

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Water flooding behavior in flow cells for ammonia production via electrocatalytic nitrogen reduction

The green production of ammonia, in an electrochemical flow cell under ambient conditions, is a promising way to replace the energy-intensive Haber-Bosch process. In the operation of this flow cell...

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Effect of cryogenic cycling on mechanical properties of ZrTiCuNiBe bulk metallic glass

The effect of deep cryogenic cycle treatment (DCT) on Zr41.2Ti13.8Cu12.5Ni10Be22.5 (Vit-1) bulk metallic glass (BMG) prepared from high-purity raw materials was investigated. After DCT, no obvious rejuvenation...

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Surface chemistry considerations of gangue dissolved species in the bastnaesite flotation system

Inefficient flotation of bastnaesite remains a challenge in the production of rare earth elements. This study aimed to investigate the dissolution and adsorption behaviour of species that are commonly...

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Self-organization of unimolecular micelles in beam stream for functional mesoporous metal oxide nanofibers

The use of linear amphiphilic block copolymers as templates is an important method for the preparation of mesoporous materials. However, the obtained assemblies are usually sensitive to synthetic conditions,...

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Experimental realization of nonadiabatic holonomic single‐qubit quantum gates with two dark paths in a trapped ion

For circuit-based quantum computation, experimental implementation of a universal set of quantum logic gates with high-fidelity and strong robustness is essential and central. Quantum gates induced...

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Deciphering electrochemiluminescence generation from luminol and hydrogen peroxide by imaging light emitting layer

Electrochemiluminescence (ECL) of luminol is a luminescence process that proceeds in the presence of reactive oxygen species (e.g. hydrogen peroxide (H2O2)) at a suitable electrode potential, the reaction...

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CO2 coordination-driven top-down synthesis of a 2D non-layered metal–organic framework

•An ingenious microenvironment for defect and coordination engineering was created.•The microenvironment can reorganize the secondary building units of 3D Cu-BTC.•Partial ligand dissociation and CO2...

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Uranium isotopes of aeolian dust deposited in northern Tibetan Plateau glaciers: Implications for tracing aeolian dust provenance

Asian dust comprises a large portion of the northern hemisphere atmospheric dust load, thereby exerting substantial influence on the Earth's climate, global biogeochemistry and hydrological cycle through...

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Root exudate chemistry affects soil carbon mobilization via microbial community reassembly

•Root exudates play an important role in regulating microbial communities and C.•Three common groups of root exudates have contrasting effects on soil C and Fe.•Sugar's application strongly reduced...

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Planted forest is catching up with natural forest in China in terms of carbon density and carbon storage

Over the last several decades, China has taken multiple measures for afforestation and natural forest protection, including setting the goal of carbon neutrality by the middle of 21th century. In order...

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Infrared stimulated emission with an ultralow threshold from low-dislocation-density InN films grown on a vicinal GaN substrate

Near-infrared stimulated emission from a high-quality InN layer under optical pumping was observed with a threshold excitation power density of 0.3 and 4 kW cm−2 at T = 8 and 77 K, respectively. To...

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An experimental and modeling study on polyoxymethylene dimethyl ether 3 (PODE3) oxidation in a jet stirred reactor

Polyoxymethylene dimethyl ether (PODEn, n ≥ 1) is a class of oxygenated fuels containing unique carbon-oxygen chain structure and a promising alternative fuel for diesel engines. In this study, low-temperature...

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Recent advances in high-βN experiments and magnetohydrodynamic instabilities with hybrid scenarios in the HL-2A Tokamak

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The blood-brain barrier in health, neurological diseases, and COVID-19

The blood-brain barrier (BBB) is a protective interface between the central nervous system (CNS) and the circulating blood, and is critical in controlling the movement of ions, molecules and cells to...

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Multiple access interference suppression for CDMA systems via ℓ∞-minimization

A key problem in code-division multiple access (CDMA) system is to mitigate the multiple access interference (MAI) from other users while detecting the desired user. The performance of the conventional...

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Vitamin B12-auxotrophy in dinoflagellates caused by incomplete or absent cobalamin-independent methionine synthase genes (metE)

•The genetic basis of B12 auxotrophy in dinoflagellates is examined systematically.•B12-dependent gene metH express responsively to B12 level in all dinoflagellates.•Most species have incomplete B12-independent...

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Entropy engineering in inorganic non-metallic glass

•The concept of entropy engineering in inorganic non-metallic glasses is proposed.•The influence of entropy on glass formation behavior and physical properties of inorganic non-metallic glasses is discussed.•The...

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Contrasting phenology responses to climate warming across the northern extra-tropics

Climate warming has substantially advanced the timing of spring leaf-out of woody species at middle and high latitudes, albeit with large differences. Insights in the spatial variation of this climate...

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Complex system management in the post-COVID world: Five research directions

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In situ characterization of vacancy ordering in Ge-Sb-Te phase-change memory alloys

Tailoring the degree of structural disorder in Ge-Sb-Te alloys is important for the development of non-volatile phase-change memory and neuro-inspired computing. Upon crystallization from the amorphous...

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Flexible bidirectional self-powered photodetector with significantly reduced volume and accelerated response speed based on hydrogel and lift-off GaN-based nanowires

•A flexible bidirectional detector is realized by nanowires and hydrogel•The detector volume is reduced successfully from ∼482 to only 0.18 cm3•Break the limitation to wear bidirectional photoelectrochemical...

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Parity-dependent unidirectional and chiral photon transfer in reversed-dissipation cavity optomechanics

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Recent progress on mechanisms that allocate cellular space to plastids

Mechanisms that allocate cellular space to organelles are of fundamental importance to biology but remain poorly understood. A detailed understanding of mechanisms that allocate cellular space to plastids,...

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Nonequilibrium thermodynamics in cavity optomechanics

Classical thermodynamics has been a great achievement in dealing with systems that are in equilibrium or near equilibrium. As an emerging field, nonequilibrium thermodynamics provides a general framework...

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