Inverse thermal design method for heat exchangers via digital twin model integrating deep learning surrogates with local thermal resistance evaluation
Available online 7 April 2026
This paper introduces an inverse design method for plate-fin heat exchangers (PFHEs) integrating digital twin, deep learning and inversion algorithm, which significantly differs from the conventional...
Genetic and linguistic landscapes of Gansu-Qinghai populations
Available online 7 April 2026
The Gansu-Qinghai (GQ) region is a critical Eurasian contact zone with exceptional linguistic and genetic diversity. However, genomic studies integrating genetic and linguistic evidence in areas with...
Chromatin regulator expression patterns predict prognosis and guide neoadjuvant therapy in esophageal squamous cell carcinoma
Available online 6 April 2026
Chromatin regulators (CRs), as key components of the epigenetic machinery, participate in tumor progression and therapeutic resistance by modulating chromatin structure and gene expression. Nonetheless,...
Dietary supplementation with fish oil, genetic risk, and glycemic control in patients with type 2 diabetes
Available online 5 April 2026
The effect of marine n-3 polyunsaturated fatty acids (PUFA) on glucose control among patients with type 2 diabetes (T2D) remains contentious. Whether the genetic risk modifies the effect remains unknown....
Dynamic roles of reactive iron in organic carbon preservation in marine sediments
Available online 4 April 2026
Iron oxides play a crucial role in carbon sequestration in marine sediments by forming associations with organic carbon (OC). However, iron oxides actively participate in sedimentary biogeochemical...
Optimizing the enterprise inclusion threshold setting of China's national carbon market
March 2026
In July 2021, China launched its national carbon emission trading system (ETS), initially targeting thermal power plants with annual emissions exceeding 26,000 tons of carbon dioxide (CO2). Optimizing...
Building a global early-warning system for environmental risks with remote sensing
March 2026
Amid intensifying environmental risks, including climate change, biodiversity loss, and pollution, global ecosystems are under unprecedented pressure. Environmental monitoring forms the cornerstone...
Capture and identification of the electrogenerated picosecond intermediates by mass spectrometry
March 2026
•In-situ generation of electrochemical intermediates during electrospray ionization.•The first mass spectrometric identification of picosecond nitrenium/oxenium ions.•The first direct observation of...
Selective oxidation by TS-1 coupled with in-situ synthesised H2O2
March 2026
Feedstock valorisation with preformed H2O2 in conjunction with titanosilicate zeotypes is particularly attractive due to the increased selectivity, lower operating temperatures and improved process...
Designing precision measurement of the gravitational Aharonov-Bohm effect in microgravity
March 2026
Refinement of selective hydrogenation catalysts guided by the concept of ‘group recognition’
March 2026
Selective hydrogenation is crucial in the production of high-value chemicals, yet its efficient implementation remains challenging due to the absence of clear catalyst regulation strategies and in-depth...
Multiple Brillouin zone folding based broadband topological slow light in valley photonic crystals
March 2026
Seasonal variations of primary biological and biomass burning aerosols in the central Himalayas
March 2026
Organic aerosols from biomass burning and primary biological sources are ubiquitous in the Earth’s atmosphere. These aerosols have a significant impact on the absorption and scattering of solar radiation,...
Targeting fatty acid metabolism for cancer therapy
March 2026
As the main component of lipids, fatty acids are essential in supporting life activities regarding energy supply, cell composition, and signaling molecules. Enhancement of fatty acid (FA) synthesis,...
Joint effects of sleep behaviors and physical activity on brain structure and cognitive function
March 2026
Sleep behaviors and physical activity (PA) are widely used to predict the risk of neurodegenerative disease. However, how sleep and PA interact to influence brain and cognitive health remains unknown....
A key heavy metal-binding protein orchestrates plant resistance against a geminivirus
March 2026
Heavy metal-binding proteins (HMPs) are crucial for heavy metal ion transportation in plants, which is involved in plant nutrient absorption, morphogenesis, and immune responses. However, the molecular...
The separation and compactness on fuzzy partial metric spaces
March 2026
In this paper, we primarily examine various topological properties within fuzzy partial metric spaces (FPMS). First, we investigate the separation axioms of FPMS and demonstrate that the T2, T3, and...
Multiscale modeling and simulation for anomalous and nonergodic dynamics: From statistics to mathematics
March 2026
In recent decades, anomalous and nonergodic diffusions are topical issues in almost all disciplines. In 2004, the phrase “anomalous is normal” was used in a title of a Physical Review Letters (PRL)...
Mesoporous microparticles based on 3D confined self-assembly of block copolymers
March 2026
Recently, 3D confined self-assembly (3D-CSA) of block copolymers (BCPs) has emerged as an advanced strategy for the preparation of microparticles with ordered mesostructures owing to the benefits of...
Harmine ameliorates steroid-induced osteonecrosis of the femoral head by modulating metabolism and ferroptosis via HIF1-α
March 2026
Steroid-induced osteonecrosis of the femoral head (SONFH) often leads to disability in the terminal stage, and there are still no effective drugs for prevention. Harmine (Hm), which is extracted from...
Contrasting foliar nitrogen nutrition of coexisting temperate and boreal trees across a modest temperature cline
March 2026
The temperate-boreal forest ecotone represents a transition zone from temperate to boreal forest where nitrogen (N) is frequently limiting tree growth. However, the spatial patterns and potential drivers...
Earthworm gut’s potential positive impact on carbon cycle by influencing carbohydrate metabolism and microbial genome size
March 2026
•Earthworm gut had higher proportion of glycosyl transfer genes than soil.•Earthworm gut had higher proportion of carbon fixation genes in arable systems.•Earthworm gut eukaryome had large genome size...
Base-assisted elemental sulfur-based multicomponent polymerizations to synthesize asymmetric polythioureas
March 2026
Polythioureas with great potential in precious metal recovery materials, dielectric materials, light refractive materials, self-healing materials, and adhesives have become a group of popular polymer...
