Metasurface-tuned light-matter interactions for high-performance photodetectors
January 2026
Photodetection, the conversion of optical signals to electrical signals, plays a pivotal role in optical communication, sensing, and computing. However, with the advent of novel applications such as...
Application of artificial intelligence in life science: Historical review and future perspectives
January 2026
The fast advancement of artificial intelligence (AI) technologies in recent years, especially the deep learning algorithm and transformer neural network, has brought great impacts on scientific researches....
Biointerface interaction regulation based on organic semiconducting polymers
January 2026
In complex biological systems, physical factors such as light and thermal energy affect normal physiological processes. When exposed to light stimulation, organic semiconducting polymers (OSPs) alter...
Perspectives on zinc-based flow batteries
January 2026
Zinc-based flow battery technologies are regarded as a promising solution for distributed energy storage. Nevertheless, their upscaling for practical applications is still confronted with challenges,...
Research progress and perspectives on ecological processes and carbon feedback in permafrost wetlands under changing climate conditions
January 2026
Permafrost wetlands are closely related to potential greenhouse gas emissions under climate warming. In recent decades, climate change and human activities have induced extensive permafrost degradation,...
The evolving landscape of spatial proteomics technologies in the AI age
January 2026
Although single-cell technologies have provided deep insights into cellular heterogeneity and complexity, they fall short in explaining how cells form tissue structures, a crucial aspect for understanding...
Contrasting patterns for bacteria and archaea in response to salt stress across alpine wetlands of the Tibetan Plateau
January 2026
Understanding microbial responses to environmental stress is crucial for comprehending their distribution and supporting conservation efforts. Yet, comprehensive evaluations of these responses across...
Molecule generation for drug design: A graph learning perspective
January 2026
•This survey offers a comprehensive overview of state-of-the-art methods in molecule design, particularly focusing on 2D de novo molecule generation models.•We categorize these methods into three distinct...
Decoding intrinsically disordered regions in biomolecular condensates
January 2026
Biomolecular condensates comprise a diverse array of molecular entities, with intrinsically disordered regions (IDRs) receiving mounting attention due to their pivotal roles. In recent years, significant...
Response of rice production to rising CO2 and its adaptive cultivation strategies
January 2026
Rice is the staple food for more than half of the population in China. Therefore, enhancing the grain yield of rice is the core of ensuring food security. In recent decades, the increase of atmospheric...
Self-powered decentralized water treatment clean boat with electrochemical fenton system for antibiotic remediation in natural water bodies
January 2026
Decentralized solutions for the low-cost and sustainable treatment of large-scale natural water bodies contaminated with organic pollutants are urgently needed. This study introduces a self-powered...
Multiple conformational states assembly of multidomain proteins using evolutionary algorithm based on structural analogues and sequential homologues
January 2026
With the breakthrough of AlphaFold2, nearly all single-domain protein structures can be built at experimental resolution. However, accurate modelling of full-chain structures of multidomain proteins,...
Jumping in the human brain: A review on somatic transposition
January 2026
As a Nobel Prize-winning discovery, transposable elements, or “jumping genes”, have attracted significant interest due to their roles in providing functional coding and regulatory sequences. A longstanding...
Biological sequence analysis: Advances, medical applications, and challenges
January 2026
With continuous developments in biotechnology and information technology, we are entering the era of biological sequence big data. Extracting valuable insights from large-scale data to decipher life...
Application of stellate ganglion modulation in mental disorders and the future prospects of physical therapies
January 2026
The treatment of mental disorders faces significant challenges due to their complex etiology and the limitations of existing therapies. Neuromodulation has emerged as a promising approach for managing...
Enhanced hole transport of nonpolar InGaN-based light-emitting diodes with lateral p-type superlattice doping structure
January 2026
In this work, we propose a novel structure for nonpolar (10–10)-plane InGaN-based light-emitting diode (LED) using a lateral p-type Al0.2Ga0.8N/GaN superlattice structure as the hole injection layer....
Mef2d regulates mutually exclusive expression of IgZ and IgM isotypes through epigenetic modulation in a zebrafish model
January 2026
The discovery of IgZ, or its counterpart IgT, represents a novel immunoglobulin isotype (named ζ or τ) found in teleosts, introducing a new member to the existing Ig classes (µ, δ, γ, α, and ε) among...
Development of double-layer FF peptide microrod arrays for high performance piezoelectric nanogenerators
January 2026
Piezoelectric biomaterials have shown good energy conversion capability and promising future for biomedical applications. However, their performance is still limited by their relatively low piezoelectric...
Rethinking structural safety for a volatile century
January 2026
Most structural design frameworks remain rooted in outdated assumptions: that hazards occur in isolation, materials do not degrade, and failure can be prevented through overdesign. In an era marked...
Data tells the truth: A Knowledge distillation method for genomic survival analysis by handling censoring
January 2026
•Supervision Bias Correction: The proposed method, KD (Knowledge Distillation), effectively addresses the supervision bias inherent in censored data for survival prediction. By distilling knowledge...
Disruption of the nucleocapsid-RNA condensation by punicalagin is a broad-spectrum antiviral approach
January 2026
The formation of liquid condensates by nucleocapsid (N) protein and viral RNA is a critical and highly conserved event in the life cycle of numerous viruses. Targeting this process emerges as a possible...
