Multispectral photoacoustic microscopy and NIR-II fluorescence imaging of TREM2-positive microglia in Aβ-driven Alzheimer’s pathogenesis
July 2026
•Novel TREM2-ICG probe enables dual-modal photoacoustic/NIR-II imaging.•In vivo tracking of microglial dynamics near Aβ plaques with neural context at 30 fps.•Multiscale imaging overcomes depth/field-of-view...
p53 mutation-associated prognosis across cancer types underlines hematological malignancy as an applicable cancer type to p53-rescue therapy
July 2026
Tumor suppressor p53 is mutated and thereafter loses tumor-suppressive function in about 50% of cancer cases, across nearly all cancer types. Efforts to rescue mutant p53 pharmacologically have been...
Activation of anionic redox reactions with vacancies in layered potassium manganese oxide
July 2026
Layered manganese-based oxides are promising cathode materials for potassium-ion batteries (PIBs) owing to the abundant K resources. However, their energy density is limited to the accessible redox...
Cyanido-bridged mixed-valence system: How to control the electron transfer process
July 2026
Cyanido-bridged mixed-valence compounds represent a distinctive and significant mixed-valence system. Exploring this system provides valuable insights into comprehending the intricacies of electron...
Research progress and application of solid-state nanopore fabrication based on wet etching
July 2026
Solid-state nanopores have the potential to revolutionise biomedical and molecular detection, particularly in the fields of gene sequencing, protein analysis, and ion screening, owing to their exceptional...
Distinct factors drive the progression of tau pathology in Alzheimer’s disease
July 2026
Alzheimer’s disease (AD) is the most common cause of dementia worldwide. The primary histopathological markers for AD diagnosis are extracellular amyloid plaques and intracellular neurofibrillary tangles...
Data-driven and people-centric operations: Research opportunities in retail operations
July 2026
This paper reviews advances and research trends in retail operations. Retailers can now collect and utilize granular operations and behavioral data to understand their consumers and employees and make...
One stone kills two birds: Novel recycled fiber spinning engineering for one-step yarn reinforcement and clean dyeing
July 2026
Low recycling rates of textile waste and high dyeing energy consumption are two significant challenges for the textile industry in response to the call for Carbon Neutrality. In view of this, we propose...
Molecular identity of the mechanotransduction machinery in inner ear hair cells and mechanotransduction-linked hearing loss
July 2026
Hearing is among the most sensitive sensory modalities in vertebrates, and its dysfunction can lead to hearing loss. Auditory perception within the inner ear relies on mechanosensitive hair cells and...
Improvement of mechanical properties and mechanism analysis of FMLs by ultrasonic vibration assisted hot press forming
July 2026
The low forming quality of fiber metal laminates (FMLs) limits their application in the aerospace field. As a fundamental research, FMLs high-quality forming process provides key technical support for...
Seizure type classification algorithm based on multi-dimensional brain network feature selection
July 2026
Nonreciprocal quantum optics: New effects and applications in quantum sensing
July 2026
Recent advancements in quantum techniques have enabled the design and fabrication of nonreciprocal optical devices that operate in the deep quantum regime, where quantum statistical properties play...
Dynamically adjustable topological edge states in thermal diffusion-advection system
July 2026
Topological edge states offer a powerful platform for understanding and manipulating waves, encompassing classical electromagnetic and acoustic wave systems and condensed matter systems. Though topological...
Mathematical foundation of the UN(1) quantum geometric tensor
July 2026
In this paper, we systematically establish the mathematical foundation for the UN(1) quantum geometric tensor (QGT) of mixed states Explicitly, we present a description based on the UN(1) principal...
Future mobile information networks: Fundamental theories, network architectures, key technologies, and key devices
July 2026
Against the backdrop of the commercialization of 5G-Advanced (5G-A) and the conceptualization of 6G, the Mobile Information Network (MINet)—a futuristic network paradigm centered on extreme connectivity...
Geometric deep learning-enabled metal-binding site identification and grafting
July 2026
Metal-binding sites can participate in enzymes’ catalytic reactions, as well as in protein folding, stability, and protein-protein interactions. In-depth research on metal-binding sites can aid in identifying...
Regulation of α-bergamotene biosynthesis by the LcDOF5.8-LcTPSbms regulatory module in litchi fruit
July 2026
Bergamotene, a key sesquiterpene compound, is crucial for defining the fruity aroma. However, the precise regulatory mechanisms governing its biosynthesis have been largely elusive. In this study, we...
DiffRIS: Enhancing referring remote sensing image segmentation with pre-trained text-to-image diffusion models
July 2026
Referring remote sensing image segmentation (RRSIS) enables the precise delineation of regions within remote sensing imagery through natural language descriptions, serving critical applications in disaster...
Neural network-based interface reconstruction algorithm for two-phase fluid flow
July 2026
In two-phase fluid flow, the vapor-liquid interface tends to behave as a curved shape under the influence of surface tension. Curve reconstruction favors improving the resolution of bubbles or droplets...
Electronic modulation of PtCo catalysts by topological carbon defects boosting durable oxygen reduction reaction in acidic media
July 2026
Pt-carbon materials are identified as state-of-the-art electrocatalysts for oxygen reduction reaction (ORR). However, it is still a big challenge to reduce the usage of Pt while maintaining the high...
Photonic biosensors based on nanoparticle superstructures: from data analysis to artificial intelligence (AI) detection
July 2026
The superstructures formed by the self-assembly of nanoparticles (NPs) can exhibit unique photonic collective properties (structural color, localized surface plasmon resonance [LSPR]), enhance the interaction...
