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ISSN: 2667-3258
CN: 10-1722/N
p-ISSN: 2096-9457

The clinical features and potential mechanisms of cognitive disorders in peripheral autoimmune and inflammatory diseases

According to a study from World Health Organization's Global Burden of Disease, mental and neurological disorders have accounted for 13% of global diseases in recent years and are on the rise. Neuropsychiatric...

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Fibroblasts: New players in the central nervous system?

Fibroblasts are typically described as cells that produce extracellular matrix, contribute to the formation of connective tissue, and maintain the structural framework of tissues. Fibroblasts are the...

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The top-order energy of quasilinear wave equations in two space dimensions is uniformly bounded

Alinhac solved a long-standing open problem in 2001 and established that quasilinear wave equations in two space dimensions with quadratic null nonlinearities admit global-in-time solutions, provided...

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Meningeal lymphatic vasculature, a general target for glioblastoma therapy?

Glioblastoma (GBM) causes nearly universal mortality as a result of the failure of conventional therapies including surgical resection, targeted radiation therapy, and chemotherapy. An increasingly...

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Scavenging and release of REE and HFSE by Na-metasomatism in magmatic-hydrothermal systems

Exploitable or potentially exploitable deposits of critical metals, such as rare-earth (REE) and high-field-strength elements (HFSE), are commonly associated with alkaline or peralkaline igneous rocks....

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Market-based solution in China to finance the clean from the dirty

Financial incentives play a key role in promoting renewable energy investments that can help China achieve the ‘dual carbon’ goal. The national emissions trading scheme (ETS) and the renewable energy...

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Quantitative analysis of the morphing wing mechanism of raptors: Analysis methods, folding motions, and bionic design of Falco Peregrinus

Raptors can change the shape and area of their wings to an exceptional degree in a fast and efficient manner, surpassing other birds, insects, or bats. Some researchers have focused on the functional...

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Immunology reshapes neuroscience, and neuroscience reshapes immunology

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Stretchable poly[2]rotaxane elastomers

Mechanically interlocked polymers (MIPs) are promising candidates for the construction of elastomeric materials with desirable mechanical performance on account of their abilities to undergo inherent...

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2.4 V ultrahigh-voltage aqueous MXene-based asymmetric micro-supercapacitors with high volumetric energy density toward a self-sufficient integrated microsystem

Two-dimensional MXenes are key high-capacitance electrode materials for micro-supercapacitors (MSCs) catering to integrated microsystems. However, the narrow electrochemical voltage windows of conventional...

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Skull and vertebral bone marrow in central nervous system inflammation

Emerging evidence has highlighted the capacity of hematogenous cells in skull and vertebral bone marrow to enter the meningeal borders via ossified vascular channels and maintain immune homeostasis...

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Revealing the vertical structure of in-situ fabricated perovskite nanocrystals films toward efficient pure red light-emitting diodes

The development of efficient perovskite light-emitting diodes (PeLEDs) relies strongly on the fabrication of perovskite films with rationally designed structures (grain size, composition, surface, etc.)....

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Celastrol regulates the oligomeric state and chaperone activity of αB-crystallin linked with protein homeostasis in the lens

Protein misfolding and aggregation are crucial pathogenic factors for cataracts, which are the leading cause of visual impairment worldwide. α-crystallin, as a small molecular chaperone, is involved...

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The cooperative migration dynamics of particles correlates to the nature of hexatic–isotropic phase transition in 2D systems of corner-rounded hexagons

In the two-dimensional (2D) melting transition of colloidal systems, the hexatic–isotropic (H–I) transition can be either first-order or continuous. However, how particle dynamics differs at the single-particle...

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Neuroimmune interactions and their roles in neurodegenerative diseases

The nervous system possesses bidirectional, sophisticated and delicate communications with the immune system. These neuroimmune interactions play a vitally important role in the initiation and development...

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Greening the Belt and Road Initiative: Evidence from emergy evaluation of China's provincial trade with ASEAN countries

•A sustainable trade evaluation at provincial level within the Belt and Road Initiative is performed.•The resource trade role of ASEAN countries to China's pivotal provinces is explored.•Existing trade...

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A neuromorphic device mimicking synaptic plasticity under different body fluid K+ homeostasis for artificial reflex path construction and pattern recognition

The ionic environment of body fluids influences nervous functions for maintaining homeostasis in organisms and ensures normal perceptual abilities and reflex activities. Neural reflex activities, such...

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Neuroimmune regulation in the pancreas

The pancreas exerts endocrine and exocrine functions in energy balance. The neural innervation and immune milieu are both crucial in supporting pancreatic homeostasis. The neuronal network connects...

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Polymeric viologen-based electron transfer mediator for improving the photoelectrochemical water splitting on Sb2Se3 photocathode

The photogenerated charge carrier separation and transportation of inside photocathodes can greatly influence the performance of photoelectrochemical (PEC) H2 production devices. Coupling TiO2 with...

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Skin neuropathy and immunomodulation in diseases

Skin is a vital barrier tissue of the body. Immune responses in the skin must be precisely controlled, which would otherwise cause severe disease conditions such as psoriasis, atopic dermatitis, or...

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Lensless camera: Unraveling the breakthroughs and prospects

Lensless imaging is an innovative and swiftly advancing technology at the intersection of optics, imaging technology, and computational science. It captures scene by directly recording the interference...

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Atomic single-molecule imaging by the confinement methods in advanced microscopy

Atomic single-molecule imaging has drawn extensive attention for exploring different behaviors and properties of small molecules. However, current techniques still face challenges, due to the thermal...

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Carrier-free delivery of nucleic acid and photosensitizer nanoparticles for enhanced photodynamic and gene antitumour therapy

Activated anti-oxidation reactions in cells partially diminish the anticancer effect of photodynamic therapy (PDT), significantly hindering efforts to increase the efficacy of PDT. The expression of...

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