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Open access

ISSN: 2405-6650
CN: 10-2053/X
e-ISSN: 2405-6642
p-ISSN: 2405-6650

Dicofol Disrupts Hematopoiesis and Immune Homeostasis in Association with Nrf2/ARE Signaling Dysregulation and Oxidative Stress

Hematotoxicity and immunotoxicity are common adverse effects observed in fish exposed to environmental pollutants; however, the molecular mechanisms underlying these toxicities remain poorly understood....

Combined estrogenic effects of mycotoxin zearalenone with other phyto-, xeno-, and mycoestrogens on Tg(vtg1:mCherry) zebrafish embryos

Zearalenone (ZEN) is mycoestrogen that is produced by Fusarium fungi. Despite the increasing recognition that humans and wildlife are typically exposed to complex mixtures of endocrine-disrupting chemicals...

Environmental Behavior of Pharmaceuticals and Personal Care Products across the Soil–Vadose Zone–Groundwater Continuum: Interfacial Interactions, Dynamic Transport, Transformation Risks, and Management

This review develops a continuum- and mass-flux-centered framework for pharmaceuticals and personal care products (PPCPs) across soil, the vadose zone, the capillary fringe, and groundwater. For 15...

Physical and Chemical Behavior of 'Permanent Chemical' PFOA and Its Substitute GenX at the Air-Water Interface: A Systematic Review

As one of the representative emerging contaminants (ECs), perfluorooctanoic acid (PFOA) is facing global prohibitions due to its environmental persistence and biological toxicity. Consequently, hexafluoropropylene...

Microwave Heating and Freeze-Thaw Cycles Exacerbate Microplastics and Nanoparticles Release from Plastic Takeout Food Containers: Characterization and Health Risk Assessment

With the rapid development of the food delivery industry, plastic takeout food containers have become essential in daily life. However, these containers may release microplastics and nanoparticles during...

From occurrence to prioritization: a neurotoxicity-informed assessment of psychoactive substances in the Yangtze River basin

Psychopharmaceuticals and illicit drugs (PIDs) are designed to modulate neural pathways, yet their ecological risks are frequently underestimated by traditional assessments that rely on apical endpoints...

Seawater-sediment partitioning, source apportionment and ecological risk of organophosphate esters in the Bohai Sea and Northern Yellow Sea, China

Organophosphate esters OPEs are pervasive emerging pollutants endangering semi-enclosed marine ecosystems under intense anthropogenic stress. In May 2023 we collected surface seawater and sediment samples...

Spatiotemporal heterogeneity and source apportionment of endocrine disrupting compounds and antibiotics in the Erhai Lake basin

Endocrine-disrupting chemicals and antibiotics are prevalent in aquatic environments, where they accumulate persistently, posing significant ecological risks that have become a topic of active research...

Occurrence and ecotoxicological risk of Perfluoroalkyl Substances (PFAS) in surface waters and sediments collected in Amazonian rivers around the city of Manaus/Brazil

As the world's largest tropical ecosystem, the Amazon basin is particularly vulnerable to chemical stressors. However, knowledge on the presence and behaviour of per- and polyfluoroalkyl substances...

Spatiotemporal patterns, loads, and risks of microplastics in the stormwater system of a subtropical coastal city

Urban stormwater runoff is a critical pathway for microplastics (MPs) to enter marine ecosystems, posing a significant threat. However, systematic studies on spatiotemporal patterns, loads, and risks...

Subchronic ephedrine exposure suppresses PPAR signalling and impairs neurobehaviour in adult zebrafish

Pharmaceutical contamination of freshwater systems by psychoactive compounds has intensified globally, yet the sub-lethal neurological consequences for resident aquatic fauna remain largely unresolved....

Comprehensive insights into the occurrence, risk assessment, and prioritization of pesticides within a typical river basin on a tropical island in China

Pesticides are prevalent in water and sediments in aquatic systems, posing risks to aquatic organisms and human health. In this study, a total of 54 pesticides, including 25 organochlorine pesticides...

Toxicological impact of polyvinyl chloride microplastic-contaminated food: Evidence from a mouse model

Microplastic pollution has emerged as a critical environmental and public health concern, induced by the widespread presence and toxicity of various polymers across diverse environments, food systems,...

Unveiling bacterial community structure and antibiotic resistance genes in coastal water of Manila Bay, Philippines using metagenomic and qPCR approaches

The widespread occurrence of antibiotic-resistant bacteria and antibiotic resistance genes (ARGs) in non-clinical settings have become increasingly recognized, particularly in aquatic environments,...

Effect of nickel oxide nanoparticles on the toxicity and accumulation of atrazine in soybean

Nickel oxide nanoparticles (NiO-NPs) could impact the behavior of contaminants in the environment and affect nutrient uptake and growth of plants. In this work, we have studied the effects and mechanisms...

Hydrogeochemical drivers of antimicrobial resistance (AMR) in the Maipo River basin, Chile: The role of treated wastewater effluent

Antimicrobial resistance remains an imminent and serious public health challenge. Wastewater presents an important reservoir for antimicrobial resistance evolution and transmission in the environment....

Insights into the occurrence and environmental behavior of legacy and emerging PFAS in the Three Gorges Reservoir region: Tributary deserves further attention

Transport of per- and polyfluoroalkyl substances (PFAS) to the Yangtze River is a growing concern because the river provides drinking water for over 400 million people. However, tributary PFAS inputs...

Human biomonitoring of PFAS and metals in relation to diabetic kidney disease: Evidence from NHANES and machine learning interpretation

Diabetic kidney disease (DKD) represents a growing health burden as the prevalence of diabetes continues to rise. Beyond traditional metabolic risk factors, environmental exposures may provide additional...

Concentration distributions, risk assessment and socioeconomic drivers of nine typical endocrine-disrupting chemicals in China's water environment

Endocrine-disrupting chemicals (EDCs) are emerging pollutants widely detected in water environments, raising concerns due to their interference with hormonal systems and potential ecological and public...

Benzophenone elicits lipid metabolic toxicity via multiple targets: integrated analysis from in vitro experiments to adverse outcome pathway

Benzophenones (BPs) are widely used as ultraviolet filters and are well recognized to possess endocrine-disrupting properties. However, their effects on lipid metabolism remain poorly understood. In...

The associations between bisphenol compounds and cardiovascular health: A narrative review of the available epidemiological evidence

Cardiovascular diseases (CVDs) remain the leading cause of global mortality, with growing evidence suggesting that exposure to environmental contaminants, such as bisphenol compounds, may serve as a...

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