Solution landscape of reaction-diffusion systems reveals a nonlinear mechanism and spatial robustness of pattern formation
Available online 27 October 2025
highlights•We propose a generic and efficient numerical algorithm to systematically construct the complete solution landscape of reaction-diffusion systems.•We demonstrate that Turing instability is...
Pure Oxygen Terminated MXenes Prepared by NaOH/NaI Eutectic Molten Salt
Available online 24 October 2025
MXenes, a promising class of two-dimensional materials derived from transition metal carbides and nitrides, are attracting considerable attention for their remarkable properties and potential uses in...
Challenges and Fundamental Theoretical Problems of Super-converged Generative Information Network
Available online 24 October 2025
Super-converged generative information network (SoGIN) envisions the integration of human-physical and digital networks, with development requirements centered on space-air-ground integration, computing-storage-sensing-intelligence...
Application of Stellate Ganglion Modulation in Mental Disorders and the Future Prospects of Physical Therapies
Available online 23 October 2025
The treatment of mental disorders faces significant challenges due to their complex etiology and the limitations of existing therapies. Neuromodulation has emerged as a promising approach for managing...
How a healthy lifestyle mediates socioeconomic inequities in healthy ageing and life expectancies: a 20-year cohort of older adults
Available online 23 October 2025
Lower socioeconomic status (SES) is associated with various adverse health outcomes, but its association with healthy ageing is less known, and whether adherence to a healthy lifestyle at late-life...
Biointerface Interaction Regulation based on Organic Semiconducting Polymers
Available online 22 October 2025
In complex biological systems, physical factors such as light and thermal energy affect normal physiological processes. When exposed to light stimulation, organic semiconducting polymers (OSPs) alter...
Polarization control enabled by on-chip three-dimensional rotator
Available online 19 October 2025
Precise polarization control is fundamental for applications such as optical communication and quantum information processing. Femtosecond-laser written photonic integrated circuits (PICs) offer the...
Hardware-enhanced Data Security for Internet of Things
Available online 19 October 2025
The Internet of Things (IoT) has become deeply embedded in daily life, enabling pervasive collection of user and environmental data. However, securing sensor-edge-cloud IoT architectures remains a critical...
One-DoF Robotic Design of Overconstrained Limbs with Energy-Efficient, Self-Collision-Free Motion
Available online 16 October 2025
•Proposed a generalized gradient-based design approach for linkage-based robotic limbs with self-collision-free motions.•Developed a computational design framework by optimizing the similarity and energy-related...
Physical Biomedical Science
Available online 15 October 2025
AI for biology: Catalyzing interdisciplinary innovation to unravel life’s complexity and address biomedical challenges
Available online 15 October 2025
Regret Bound for Multi-Armed Bandits with Discounting: a Robust Stochastic Control Approach
Available online 15 October 2025
We investigate the exact regret bound for stochastic multi-armed bandit problems with discounting, by formulating the regret bound as the value of a robust stochastic control problem. We first show...
The scale-selective role of orography in shaping global atmospheric dynamics: From resolved orographic effects to parameterized drag biases
Available online 14 October 2025
Orographic effects on circulation operate across multiple spatial scales through complex processes, yet the scale-selective characteristics of these interactions remain insufficiently quantified. In...
Single-cell profiling reveals immune cell diversity and infection-driven remodeling in the spleen of marine teleost Larimichthys crocea
Available online 13 October 2025
•First single-cell atlas of L. crocea spleen reveals diverse immune-cell types with mammalian conservation.•Pseudomonas infection spurs neutrophil surge, B cell loss, and progenitor expansion via hematopoietic...
Bulk films vs colloidal nanocrystals: the photoactive layers in perovskite solar cells
Available online 3 October 2025
Perovskite solar cells have attracted significant attention because of their superior photovoltaic performance and promising potential for commercialization. Two distinctive photoactive layers have...
Lignin-mediated atomic coordination engineering of Ru nanoclusters with self-optimized Mott-Schottky interfaces for industrial hydrogen production
Available online 2 October 2025
The global transition toward carbon neutrality urgently demands scalable green hydrogen technologies driven by renewable energy. While water electrolysis represents a key pathway, current anion exchange...
Multiple Brillouin zone folding based broadband topological slow light in valley photonic crystals
Available online 1 October 2025
Detection of the characteristic magnetic signal of paclitaxel and its application in the inhibition of glioma cells
September 2025
Glioma, a type of brain tumor, is one of the most challenging cancers for human beings due to its genetic heterogeneity, high recurrence rate and difficulty of effective treatment. To explore a novel...
The application of antibody-based agents in cancer therapy based on their mechanisms of action
September 2025
Monoclonal antibodies and antibody-based agents are undergoing remarkable development in cancer immunotherapy. Based on their structural components, these antibodies mediate the crosslinking of tumor...
Primary cilia in growth plates orchestrate long bone development
September 2025
The growth plate plays a crucial role in long bone development and elongation, housing stem cells that contribute to bone formation. This study investigates the role of primary cilia, specialized organelles...
Gene circuit-based sensors
September 2025
As an important branch of biosensors, gene circuit-based biosensors constructed based on synthetic biology concepts can sense specific substances to be measured and converted into specific signal outputs....
Nanoscale synthetic biology with innovative medicinal applications
September 2025
The rapid advancement of synthetic biology and nanoscience has given rise to a new research field, known as nanoscale synthetic biology (NSB). This field emphasizes the interactions and coordination...
Nano-oncology revisited: Insights on precise therapeutic advances and challenges in tumor
September 2025
The integration of nanotechnology with cancer therapy has revolutionized traditional diagnostic and treatment methods, giving rise to the new interdisciplinary field of nano-oncology. With advancements...
Under-reporting potential of inoxidizable nitrogenous organic compounds in assessing organic pollution of waters: Underlying mechanisms
September 2025
•The under-reporting potential of INOCs was determined in assessing organic pollution.•Effects of substituent groups and side chain length on CODCr/ThOD were measured.•The underlying mechanisms of INOCs...
Spatial and seasonal dynamics of biogenic silica in a eutrophic marginal sea, the East China Sea
September 2025
Biogenic silica (BSi) is a key component of the marine silicon cycle, which is mainly driven by diatom metabolism notably contributing to primary production and export of particulate organic carbon...
