Dual-Brain Fusion: Bidirectional Empowerment Between Human Brain and Brain-Inspired Systems
Available online 27 April 2026
•Propose a collaborative innovation framework integrating the human brain and brain-inspired systems, and identify the core components of this paradigm.•Analyze the key technological pathways for brain-intelligence...
Understanding the regulatory mechanisms of nanomaterials on carbon metabolism in plants
Available online 26 April 2026
Agricultural nanotechnology offers innovative strategies to enhance crop productivity by modulating fundamental physiological processes in plants. Despite growing evidence that nanomaterials (NMs) can...
Phanerozoic continental black shales and their coupling with astronomical cycles: A review and prospects
Available online 25 April 2026
Black shales preserve critical records of paleoclimate and carbon cycling, reflecting coupled interactions within the Earth system and serving as key archives for Earth system evolution and unconventional...
Higher microbial community stability promotes the link between biodiversity and multifunctionality under environmental changes
Available online 25 April 2026
Unravelling the community stability under a changing climate and its effects on the relationships between biodiversity and ecosystem functions (BEF) is a challenging topic in theoretical ecology, which...
Climate-vegetation regimes dominate the divergent ecosystem responses to flash droughts in China
Available online 24 April 2026
•FD events were most frequent in humid and least in arid regions during 2001-2023.•Precipitation and temperature were identified as the dominant drivers of FD.•In China, humid-forests react to FD more...
Terrestrial carbon sequestration potential assessment: concept, method, and perspective
Available online 23 April 2026
Accurately quantifying the terrestrial ecosystems’ carbon sequestration potential (CSP) is critical for climate mitigation, ecological security, and carbon neutrality. However, current assessments are...
Enhanced soil health and greenhouse gas mitigation potential are linked to microbial network restructuring under long-term organic farming
Available online 23 April 2026
•Organic farming enhanced soil health and reduced N2O and CH4 emissions•Microbial network complexity was inversely linked with soil health under organic systems•Keystone microbial taxa regulated GHG...
A perspective on hybrid intelligent computing for geospatial science
Available online 20 April 2026
Geospatial science refers to the interdisciplinary field involving acquisition, analysis, modelling, interpretation, visualization and service of geospatial data related to Earth’s surface and human...
Amino acid insufficiency orchestrates AMPK and mTOR signaling
Available online 20 April 2026
Image, graphical abstract...
Expansion of global monsoon margins under weakened monsoon intensity
Available online 20 April 2026
Monsoon margins, often located in semi-arid zones, are ecologically fragile areas highly sensitive to climate change and socio-economic activities. However, the response of monsoon margins to global...
Biomedical imaging
Available online 17 April 2026
First Mesozoic entomofauna from the Qinghai-Tibetan Plateau
Available online 17 April 2026
Beyond place cells: Specific and cooperative roles of hippocampal interneuron families in spatial coding
Available online 16 April 2026
High-resolution mapping of soil total phosphorus in China: Revealing spatiotemporal patterns and driving mechanisms
Available online 16 April 2026
•Developed a 1 km resolution, layered spatiotemporal dataset of STP in China (2000-2020).•Revealed a macro-scale “central high, northern-southern low” pattern of STP, with a vertical decrease of 25.8%...
Metagenomic and metatranscriptomic insights into divergent mercury detoxification in the Mariana Trench sediments
Available online 15 April 2026
Mercury compounds accumulate in the Mariana Trench through sinking particles or carrion, yet the mercury cycling process and how hadal trench microbes cope with mercury toxicity remain largely unexplored....
Small-Molecule Autophagy Modulators: Mechanisms, Therapeutic Potential, and Development Challenges in Pathological Settings
Available online 15 April 2026
Autophagy is an evolutionarily conserved process in eukaryotic cells that delivers intracellular components to lysosomes for degradation and recycling. Increasing evidence has elucidated the regulation...
Geological records reveal chaotic diffusion during the Late Paleozoic Ice Age
Available online 15 April 2026
Chaotic diffusion arising from the long-term gravitational interactions between Earth and Mars has increasingly been recognized as a fundamental part of the chaotic behavior of the Solar system, yet...
Global change influences the prevalence and diversity of gut bacterial pathogens in soil invertebrates
Available online 13 April 2026
•Soil faunal gut harbors diverse potential pathogenic bacteria.•High host biodiversity help reduce the proportion of gut pathogens.•Global changes increase the proportion of gut potential pathogens.•The...
Photochemistry and haze in chemically reducing terrestrial atmospheres
Available online 13 April 2026
Properties and processes within planetary atmospheres are critical for surface habitability. Evidence from the Earth suggests that our only known form of life has likely originated in a chemically reducing...
Targeted restoration of mitochondrial function mediates autophagy and glycolysis to promote irradiation-induced bone injury repair
Available online 13 April 2026
Radiotherapy remains a critical modality for tumor eradication in clinical practice. However, the bone tissue surrounding the tumor is highly susceptible to irradiation-induced damage due to its high...
Label-free proteomics and single-cell mass cytometry analysis of 5 immune tissues from mice with artesunate administration reveal immunosuppression of artesunate via BST2 and MDSCs
Available online 12 April 2026
Artesunate is a worldwide prevalent antimalarial medicine, which has also been demonstrated for anti-tumor, anti-virus and anti-autoimmune diseases. Yet the underlying molecular and cellular mechanisms...
Label-free digital protein sensing by integral plasmonic imaging
Available online 12 April 2026
The capability to detect trace-level protein in complex biofluids is critical in various fields, from fundamental biological research to clinical disease diagnosis. Digital protein sensing by counting...
Gut microbiota mediates tissue injury by promoting proteolysis and heme bioavailability in the small intestine
Available online 10 April 2026
•Extensive hydrolysis is essential for heme release from dietary myoglobin.•Intestinal microbiota mediates extensive hydrolysis of dietary myoglobin.•Short peptides facilitate PEPT1- and F-actin-dependent...
Magnetic Catheter Robot with Dynamic Force Feedback for Stiffness Identification and Abnormality Detection
Available online 7 April 2026
Ultra-intense laser pulses: From petawatt to exawatt, from multi-cycle to single-cycle
Available online 7 April 2026
Since the laser’s invention in 1960, the pursuit of higher peak power and stronger focused intensity has never stopped. Breakthroughs in chirped pulse amplification and optical parametric chirped pulse...
