In situ 3D Bioprinting: The Future of Regenerative Medicine
Available online 9 June 2025
3D bioprinting is utilized to design and construct scaffolds with scalable forms and physicochemical properties. Recently, this technology has been extensively studied in the field of biology and has...
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Recent research progress on perylene diimide-based photocatalytic materials
Available online 8 June 2025
Perylene diimide (PDI) is an organic semiconductor with outstanding optical and electronic properties, including a rigid π-conjugated structure, high electron affinity, and chemical stability, which...
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Crystallographically Aligned Wadsley-Roth Phase Anodes with Conductive Agents for High-Rate Lithium-Ion Batteries
Available online 6 June 2025
To realize high-energy density lithium-ion batteries, achieving fast-charging capabilities for electrodes with high areal mass loadings is a significant challenge. Traditional anode materials such as...
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A special machine for solving NP-complete problems
Available online 6 June 2025
A specialized computer named as the Electronic Probe Computer (EPC) has been developed to address large-scale NP-complete problems. The EPC employs a hybrid serial/parallel computational model, structured...
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Fine-tuning of the CRWN2-NTL9 module to repress PR1 expression by a viral effector during geminivirus infection
Available online 6 June 2025
CROWDED NUCLEIs (CRWNs) are nuclear lamina proteins that play an important role in plant immunity. Nevertheless, the molecular mechanism of how CRWNs regulate host immunity and the mechanism by which...
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A Governance Framework for Blockchain-based Manufacturing Collaborative Platform
Available online 5 June 2025
The traditional manufacturing collaborative platforms (MCPs) face challenges of weak trust and innovation inhibition in the transformation and upgrading of the global industrial chain. This paper investigates...
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A Review of Simulation Optimization with Connection to Artificial Intelligence
Available online 4 June 2025
We review simulation optimization methods and their connection with artificial intelligence (AI) techniques. In particular, we focus on two areas: stochastic gradient estimation, which plays a central...
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Profiling Adaptive Immunity: A Quantitative Framework for Immune Repertoire Dynamics and Clinical Diagnostics
Available online 3 June 2025
•The article derives first-principle relationships from foundational biological assumptions, grounding the approach in deductive reasoning rather than data mining.•BCR repertoire diversity is modeled...
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Constructing High-Capacity and Ultra-Stable Biphasic Layered Cathodes via Reductive Coupling Mechanism for Sodium-Ion Batteries
Available online 3 June 2025
Stimulated anionic redox reactions are commonly utilized to design layered oxide cathodes for high-energy sodium-ion batteries (SIBs). Unfortunately, excessive oxygen redox often causes irreversible...
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Intranasal Delivery of Rotigotine to the Brain for Treating Parkinson’s Disease
Available online 2 June 2025
The development of sustainable and non-invasive method for delivering drugs to the brain is crucial for the effective treatment of Parkinson’s disease (PD). In this study, nanoparticles were formulated...
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Advances in human organs-on-chips and applications for drug screening and personalized medicine
May 2025
The limitations of conventional animal tests and two-dimensional cell culture hinder their advancement in fundamental research and clinical/translational applications. As an emerging alternative technology,...
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Nonlinearity in optomechanical microresonators –phenomena, applications, and future
May 2025
Optomechanical microresonators have received considerable attention in recent years because of their ability to realize strong light-matter interactions in both classical and quantum regimes and support...
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Chemical closed-loop recycling of polymers realized by monomer design
May 2025
The development of modern society is closely related to polymer materials. However, the improper disposal of the polymer wastes not only squanders resources but also intensifies the environmental issues,...
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AI-aided power electronic converters automatic online real-time efficiency optimization method
May 2025
Energy losses during the conversion and supply of electric power are considered a significant issue and cannot be estimated. Improvement in the efficiency of energy conversion systems is highly restricted...
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Bioinspired multi-scale core-spun yarn-based solar evaporator for ultra-efficient and durable high-salinity brine desalination
May 2025
Solar-driven interfacial desalination has been considered a promising and green technology for relieving worldwide water shortage because of its zero carbon emission. However, salt accumulation during...
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Recent progress in upcycling of plastic wastes into value-added chemicals via photo-, electro- and photoelectro-catalytic strategies
May 2025
Massive production but inadequate end-of-life management of plastics cause environment pollution and carbon resource wasting. It is desirable to develop sustainable approaches to transform plastic wastes...
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Apigenin alleviates osteoporosis by orchestrating SIRT1/HIF1α signaling in mesenchymal stem cells
May 2025
Osteoporosis (OP) is a systemic skeletal disease characterized by reduced bone mass and a degenerative bone microarchitecture. Apigenin (API), a flavonoid derived mainly from celery, has been reported...
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Atmospheric impacts and regulation framework of shipping emissions: Achievements, challenges and frontiers
May 2025
Currently, over 80% of the international trade volume is carried by sea. Marked by persistent growth, evident atmospheric impacts, intricate mitigation challenges, international shipping has been recognized...
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Lenalidomide promotes melarsoprol-activated cGAS-STING-mediated immunotherapy for hepatocellular carcinoma via attenuating TNF-α activity
May 2025
Current immunotherapy has limited efficacy in hepatocellular carcinoma (HCC) due to the immunosuppressive tumor microenvironment (TME). The activation of the cyclic guanosine monophosphate-adenosine...
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Engineered bacteria: Strategies and applications in cancer immunotherapy
May 2025
Cancer therapy remains a critical medical challenge. Immunotherapy is an emerging approach to regulating the immune system to fight cancer and has shown therapeutic potential. Due to their immunogenicity,...
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Unexpected d–p orbital covalent interaction between the non-d-block main-group metal tellurium and fluorine at high pressure
May 2025
•A pressure-induced d–p orbital covalent interaction in Te-F compound.•The F ligand field affects the valence orbital energies of the central metal atom.•High pressure is an effective method to regulate...
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Chemical recycling of waste plastics: Current challenges and perspectives
May 2025
Waste plastics offer valuable feedstock for refining facilities. Their well-structured molecular compositions and functional groups make them ideal candidates for conversion into high-value chemicals...
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Investigating the central place theory using trajectory big data
May 2025
The human settlement system is central to land use, infrastructure development, and environmental impacts. Although central place theory (CPT) was proposed about 90 years ago and has been extensively...
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