Nanoparticle-based drug delivery systems for cancer therapy
2020
Nanoparticle-based drug delivery system (DDS) is considered promising for cancer treatment. Compared with traditional DDS, the nanoparticle-based DDS shows improved efficacy by: 1) increasing half-life...
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Smart materials for smart healthcare– moving from sensors and actuators to self-sustained nanoenergy nanosystems
2020
Smart materials offer a significant role in on our lives covering various sensing and actuation applications in healthcare due to their responsivity to external stimuli such as stress, light, temperature,...
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Recent progress in surgical adhesives for biomedical applications
2022
The increasing demands for the management of hemostasis and tissue sealing drive the development of novel bioadhesives, which can overcome the disadvantages of conventional sutures such as additional...
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DNA nanostructures for stimuli-responsive drug delivery
2022
DNA molecules have shown potential for drug delivery owing to their predictability and programmability. Due to the continuous development of DNA nanotechnology and the unique properties of DNA nanomaterials,...
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Recent progress on coatings of biomedical magnesium alloy
2022
Magnesium (Mg) alloy has received thorough attention in the biomedical field due to its excellent mechanical properties, good biocompatibility, and biodegradability. However, Mg alloy usually shows...
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Recent development of implantable and flexible nerve electrodes
2020
Implantable electrical devices offer a variety of potential diagnostic options and treatments in different medical fields. Especially in the absence of specific drugs, the implantable nerve electrodes...
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Inorganic nano-carriers based smart drug delivery systems for tumor therapy
2020
Tumor is a severe disease that affects human health. In addition to surgical treatment and radiotherapy, applying therapeutic agents that can kill the tumor directly or regulate immune systems is one...
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Graphene oxide as a promising material in dentistry and tissue regeneration: A review
2021
Current treatments for common dental diseases such as caries, periodontal diseases, tooth defects, missing teeth and bone defects cannot replenish dental tissue with artificial alternatives while maintaining...
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3D-printed bioactive scaffolds for bone regeneration bearing carbon dots for bioimaging purposes
2022
Additive manufacturing, also known as 3D-printing, has been successfully employed to create novel bioactive scaffolds incorporating carbon dots for bioimaging purposes. Fused filament fabrication technique...
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Recent advances in orthopedic polyetheretherketone biomaterials: Material fabrication and biofunction establishment
2022
Polyetheretherketone (PEEK) is a kind of nontoxic high-performance thermoplastic widely used for medical applications. Compared with other special engineering plastics, PEEK has many excellent properties,...
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Charge-reversal nanomedicines as a smart bullet for deep tumor penetration
2022
Complex composition and abnormal growth state of cells and tissues in the solid tumor microenvironment often lead to high density and stiffness different from normal tissues, thus forming a solid physical...
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Extraction and isolation of Isoflavonoids from stem bark of Bauhinia purpurea (L): Its biological antipsychotic and analgesic activities
2022
The present research work reports the solvent extraction and isolation of Isoflavonoids from Bauhinia purpurea stem bark and their antipsychotic with analgesic activities were studied. Flavonoids are...
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High strength HA-PEG/NAGA-Gelma double network hydrogel for annulus fibrosus rupture repair
2022
The low back pain (LBP) caused by intervertebral disc (IVD) herniation and degeneration bring huge physical and economic burden to individuals and families. Since current clinical treatment methods...
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Inorganic-polymer composite coatings for biomedical devices
2021
Medical coatings are now playing key roles in the practical use of biomedical devices. By fabricating coatings, the biocompatibility of the devices would be significantly improved, and their biofunctions...
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Application of organic frame materials in cancer therapy through regulation of tumor microenvironment
2022
During tumorigenesis and cancer progression, tumor microenvironment (TME) is continuously remodeled and a high intertumoral heterogeneity emerges due to hypoxia, oxidative stress and acidosis, etc.,...
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High strength porous PLA gyroid scaffolds manufactured via fused deposition modeling for tissue-engineering applications
2021
Gyroid polylactic acid (PLA) scaffolds with different unit cell sizes of 2 mm (G2), 2.5 mm (G25), and 3 mm (G3) were fabricated via fused deposition modeling for bone tissue engineering applications....
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Endoplasmic reticulum-targeting nanomedicines for cancer therapy
2021
In drug development research, the specific affinity of drug delivery systems for particular pathological sites, cells, and even subcellular structures can largely reduce the side effects, systemic toxicity,...
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Sustainable wheat gluten foams used in self-expansion medical dressings
2022
Wheat gluten (WG) foam was successfully prepared by heating, stirring and freeze-drying. The effects of WG concentration, content of glycerol and glutaraldehyde on the macroscopic appearance, microstructure,...
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Stimuli-responsive materials: A smart way to study dynamic cell responses
2022
Cells in the body reside within the extracellular matrix (ECM), a three-dimensional environment that not only provides structural support for the cells, but also influences cellular processes, like...
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Anti-microbial/oxidative/inflammatory nanogels accelerate chronic wound healing
2022
The most common cause of delayed healing in chronic wounds is microbial pathogenesis, in which localized colonization can cause severe inflammation, systemic infection, and even sepsis in some cases....
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Mussel-inspired peptide mimicking: An emerging strategy for surface bioengineering of medical implants
2021
With the massive use of medical implants (e.g., metals, polymers and ceramics) in orthopedic and cardiovascular surgery, surface biomodification of these exogenous biomaterials has caused growing concern,...
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Liquid crystalline lipid nanoparticles for combined delivery of curcumin, fish oil and BDNF: In vitro neuroprotective potential in a cellular model of tunicamycin-induced endoplasmic reticulum stress
2022
We develop multidrug-loaded cubosome and spongosome lipid nanoparticles for targeting of endoplasmic reticulum stress as a potential emerging therapeutic strategy against neuronal degeneration. The...
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3D-bioprinted vascular scaffold with tunable mechanical properties for simulating and promoting neo-vascularization
2022
Alternative artificial vessels with tissue-matching mechanical and biological performance have been continuously taking great attention in bioengineering. However, it is challenging to take into account...
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Membrane fusion boosting drug transmembrane delivery
2022
Benefiting from fusion element (peptides or proteins) anchoring, several biological membrane vesicles or synthetic liposomes have great potency to fuse with the target cell membrane via virus-mimetic...
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Responsive principles and applications of smart materials in biosensing
2020
Biosensing is a rising analytical field for detection of biological indicators using transducing systems. Smart materials can response to external stimuli, and translate the stimuli from biological...
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