Nanoparticle-based drug delivery systems for cancer therapy
2020
Nanoparticle-based drug delivery system (DDS) is considered promising for cancer treatment. Compared with traditional DDS, the nanoparticle-based DDS shows improved efficacy by: 1) increasing half-life...
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Recent progress of 3D printed vascularized tissues and organs
June 2024
Since the need for vascular networks to supply oxygen and nutrients while expelling metabolic waste, most cells can only survive within 200 μm of blood vessels; thus, the construction of well-developed...
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Function and treatment strategies of β-hydroxybutyrate in aging
2023
Metabolic intermediates serve as precursors for bioactive molecule synthesis, the energy source for life activities, and signals for environmental adaptation. Ketone bodies are important metabolic intermediates...
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Inhalable nanomedicine for lung cancer treatment
June 2024
Lung cancer has surpassed other types of cancer to become the primary cause of cancer-related deaths. Surgery stands as the foremost clinical treatment strategy available for tackling this condition,...
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Journey of smart material from composite to shape memory alloy (SMA), characterization and their applications-A review
2023
This review paper deals with the advancements of composites to shape memory alloys. The journey of smart materials from conventional composites to advance shape memory alloys and their application is...
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Light-responsible ECM-mimetic scaffolds for neural differentiation. Intracellular versus extracellular photothermal stimulation
March 2025
The development of approaches and materials that combine several types of stimulatory effects on nerve tissue growth is a promising task for biotechnology. The aim of this work was a comparative study...
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Recent progress in surgical adhesives for biomedical applications
2022
The increasing demands for the management of hemostasis and tissue sealing drive the development of novel bioadhesives, which can overcome the disadvantages of conventional sutures such as additional...
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Stimuli-responsive materials: A smart way to study dynamic cell responses
2022
Cells in the body reside within the extracellular matrix (ECM), a three-dimensional environment that not only provides structural support for the cells, but also influences cellular processes, like...
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Design of 3D smart scaffolds using natural, synthetic and hybrid derived polymers for skin regenerative applications
2023
Effective wound care is a major concern as many conventional wound healing methods and materials have failed in facilitating proper healing, instead disrupts the overall healing process, leading to...
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A polymeric dexamethasone prodrug attenuates focal segmental glomerulosclerosis (FSGS) in an Adriamycin-induced mouse model with minimal glucocorticoid side effects
March 2025
Focal segmental glomerulosclerosis (FSGS) is chronic renal injury characterized by proteinuria and podocyte injury with glomerulus scarring and tubulointerstitial fibrosis. Glucocorticoids (GCs) are...
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Recent advances in hyaluronic acid-based hydrogels for 3D bioprinting in tissue engineering applications
2023
3D bioprinting technology can rapidly process cell-loaded biomaterials to prepare personalized scaffolds for repairing defective tissues, tissue regeneration, and even printing tissues or organs. 3D...
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Hydrogel wound dressings containing bioactive compounds originated from traditional Chinese herbs: A review
March 2024
Various factors can cause skin defects, resulting in the loss of physiological functions and even death due to severe concurrent infection. Dressings are often clinically used to fully cover the wounds...
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A detailed protocol for cell force measurement by traction force microscopy
March 2024
Cellular traction forces (CTFs) are generated by adherent cells and involved in regulating migration, morphology, and homeostasis. Accurate measurement of CTFs is crucial for understanding fundamental...
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Biomimetic 3D printing of photocrosslinkable biodegradable elastomers-modified hybrid scaffolds as instructive platforms for bone tissue regeneration
March 2025
3D printing is regarded as an ideal method for large-scale bone defect repair. A rapid curing rate and strong mechanical properties throughout the product's shelf life are key development goals in 3D-printed...
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Nanobody-as versatile tool emerging in autoimmune diseases
December 2024
Nanobody (Nb) is derived from the variable domain of heavy-chain antibody (HCAb), naturally displaying notable properties like nano-scale size, exceptional stability, high specificity, low immunogenicity,...
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Artificial intelligence (AI) meets biomaterials and biomedicine
June 2024
With the rapid progress of information technology and life sciences, artificial intelligence (AI) technology has substantially changed the way in many areas of biomaterials and biomedicine, including...
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Current state of art smart coatings for orthopedic implants: A comprehensive review
2023
Biomaterials play a pivotal role in modern orthopedics. There are a plethora of functional issues with orthopedic implants. These issues include things like aseptic loosening, lack of osseointegration,...
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Anti-fouling coatings for blood-contacting devices
March 2024
Blood-contacting medical devices, such as vascular stents, intravascular catheters, and artificial heart valves, frequently encounter complications in clinical practice, including thrombosis, inflammatory...
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Biosensor-based therapy powered by synthetic biology
2023
The study of synthetic biology focusing on biosensor systems has resulted from a growing interest in developing customized biological devices with desired cellular functions. Recently, biosensors have...
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Smart materials for smart healthcare– moving from sensors and actuators to self-sustained nanoenergy nanosystems
2020
Smart materials offer a significant role in on our lives covering various sensing and actuation applications in healthcare due to their responsivity to external stimuli such as stress, light, temperature,...
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Tailoring the elasticity of nerve implants for regulating peripheral nerve regeneration
2023
Numerous studies have conducted in-depth research on the biological and chemical properties of tissue-engineered neural graft (TENG) on peripheral nerve regeneration, while the physical properties of...
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Ultrasound-activated mechanochemical reactions for controllable biomedical applications
December 2024
Intramolecular bonds in small organic molecules, macromolecules, and organic-inorganic hybrids are broken or formed by ultrasound-activated mechanical force that can be applied with spatial and temporal...
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Reactive oxygen species-sensitive materials: A promising strategy for regulating inflammation and favoring tissue regeneration
2023
Reactive oxygen species (ROS), acting as essential mediators in the biological system, highly influence the physiologic and pathologic processes of the human body. The aberrant production of ROS, caused...
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A responsive hydrogel-based microneedle system for minimally invasive glucose monitoring
2023
Blood glucose (BG) monitoring in patients with diabetes is critical for diabetes management. Minimally invasive BG monitoring is urgently required to increase the patient compliance. Herein, based on...
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DNA nanostructures for stimuli-responsive drug delivery
2022
DNA molecules have shown potential for drug delivery owing to their predictability and programmability. Due to the continuous development of DNA nanotechnology and the unique properties of DNA nanomaterials,...
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