Nanoparticle-based drug delivery systems for cancer therapy
2020
Nanoparticle-based drug delivery system (DDS) is considered promising for cancer treatment. Compared with traditional DDS, the nanoparticle-based DDS shows improved efficacy by: 1) increasing half-life...
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Journey of smart material from composite to shape memory alloy (SMA), characterization and their applications-A review
2023
This review paper deals with the advancements of composites to shape memory alloys. The journey of smart materials from conventional composites to advance shape memory alloys and their application is...
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Recent advances in hyaluronic acid-based hydrogels for 3D bioprinting in tissue engineering applications
2023
3D bioprinting technology can rapidly process cell-loaded biomaterials to prepare personalized scaffolds for repairing defective tissues, tissue regeneration, and even printing tissues or organs. 3D...
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Smart materials for smart healthcare– moving from sensors and actuators to self-sustained nanoenergy nanosystems
2020
Smart materials offer a significant role in on our lives covering various sensing and actuation applications in healthcare due to their responsivity to external stimuli such as stress, light, temperature,...
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Function and treatment strategies of β-hydroxybutyrate in aging
2023
Metabolic intermediates serve as precursors for bioactive molecule synthesis, the energy source for life activities, and signals for environmental adaptation. Ketone bodies are important metabolic intermediates...
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Stimuli-responsive materials: A smart way to study dynamic cell responses
2022
Cells in the body reside within the extracellular matrix (ECM), a three-dimensional environment that not only provides structural support for the cells, but also influences cellular processes, like...
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Recent progress in surgical adhesives for biomedical applications
2022
The increasing demands for the management of hemostasis and tissue sealing drive the development of novel bioadhesives, which can overcome the disadvantages of conventional sutures such as additional...
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Recent progress on coatings of biomedical magnesium alloy
2022
Magnesium (Mg) alloy has received thorough attention in the biomedical field due to its excellent mechanical properties, good biocompatibility, and biodegradability. However, Mg alloy usually shows...
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A responsive hydrogel-based microneedle system for minimally invasive glucose monitoring
2023
Blood glucose (BG) monitoring in patients with diabetes is critical for diabetes management. Minimally invasive BG monitoring is urgently required to increase the patient compliance. Herein, based on...
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Design of 3D smart scaffolds using natural, synthetic and hybrid derived polymers for skin regenerative applications
2023
Effective wound care is a major concern as many conventional wound healing methods and materials have failed in facilitating proper healing, instead disrupts the overall healing process, leading to...
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Silk sericin-based biomaterials shine in food and pharmaceutical industries
2023
Silk sericin (SS) is a byproduct of the silk production process that consists of 18 amino acids and numerous polar groups. SS has a range of unique physical, chemical, and biological properties, such...
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Emerging polymeric biomaterials and manufacturing-based tissue engineering approaches for neuro regeneration-A critical review on recent effective approaches
2023
The nervous system is a crucial part of the human body that is damaged by traumatic injury, stroke, and neurodegenerative diseases. Recent studies also have shown that neurodegenerative diseases are...
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Eggshell-derived amorphous calcium phosphate: Synthesis, characterization and bio-functions as bone graft materials in novel 3D osteoblastic spheroids model
2023
A multitude of autogenous/allogeneic and semi-synthetic bone graft materials have been developed to reconstruct the defective bone tissue but with high bio-cost and potential environmental pollution....
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Research hotspots and trends of biodegradable magnesium and its alloys
2023
With the increasing demand for innovative therapies, biodegradable magnesium has attracted more and more attention, which could avoid secondary surgery and reduce complications. Until now, plenty of...
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Advances of multifunctional hydrogels for periodontal disease
2023
Periodontal disease is a chronic inflammatory disease that develops from dental plaque that affects periodontal supporting tissues. The control of plaque by mechanical therapy has always been the mainstream...
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Biosensor-based therapy powered by synthetic biology
2023
The study of synthetic biology focusing on biosensor systems has resulted from a growing interest in developing customized biological devices with desired cellular functions. Recently, biosensors have...
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Inorganic nano-carriers based smart drug delivery systems for tumor therapy
2020
Tumor is a severe disease that affects human health. In addition to surgical treatment and radiotherapy, applying therapeutic agents that can kill the tumor directly or regulate immune systems is one...
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Recent development of implantable and flexible nerve electrodes
2020
Implantable electrical devices offer a variety of potential diagnostic options and treatments in different medical fields. Especially in the absence of specific drugs, the implantable nerve electrodes...
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DNA nanostructures for stimuli-responsive drug delivery
2022
DNA molecules have shown potential for drug delivery owing to their predictability and programmability. Due to the continuous development of DNA nanotechnology and the unique properties of DNA nanomaterials,...
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Natural biopolyester microspheres with diverse structures and surface topologies as micro-devices for biomedical applications
2023
Based on their excellent biocompatibility and adjustable biodegradability, the two natural polyesters polylactic acid (PLA) and polyhydroxyalkanoates (PHAs) have been widely used in medical engineering...
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Endoplasmic reticulum-targeting nanomedicines for cancer therapy
2021
In drug development research, the specific affinity of drug delivery systems for particular pathological sites, cells, and even subcellular structures can largely reduce the side effects, systemic toxicity,...
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High strength porous PLA gyroid scaffolds manufactured via fused deposition modeling for tissue-engineering applications
2021
Gyroid polylactic acid (PLA) scaffolds with different unit cell sizes of 2 mm (G2), 2.5 mm (G25), and 3 mm (G3) were fabricated via fused deposition modeling for bone tissue engineering applications....
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Reactive oxygen species-sensitive materials: A promising strategy for regulating inflammation and favoring tissue regeneration
2023
Reactive oxygen species (ROS), acting as essential mediators in the biological system, highly influence the physiologic and pathologic processes of the human body. The aberrant production of ROS, caused...
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Antibacterial silk sericin/poly (vinyl alcohol) hydrogel with antifungal property for potential infected large burn wound healing: Systemic evaluation
2023
Hydrogel-based burn wound dressings with excellent antibacterial, antifungal, and mechanical properties are ideal biomaterials to promote infected large burn wound healing. In this study, the hydrogel...
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Extraction and isolation of Isoflavonoids from stem bark of Bauhinia purpurea (L): Its biological antipsychotic and analgesic activities
2022
The present research work reports the solvent extraction and isolation of Isoflavonoids from Bauhinia purpurea stem bark and their antipsychotic with analgesic activities were studied. Flavonoids are...
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