Smart materials for smart healthcare– moving from sensors and actuators to self-sustained nanoenergy nanosystems
2020
Smart materials offer a significant role in on our lives covering various sensing and actuation applications in healthcare due to their responsivity to external stimuli such as stress, light, temperature,...
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Nanoparticle-based drug delivery systems for cancer therapy
2020
Nanoparticle-based drug delivery system (DDS) is considered promising for cancer treatment. Compared with traditional DDS, the nanoparticle-based DDS shows improved efficacy by: 1) increasing half-life...
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Recent development of implantable and flexible nerve electrodes
2020
Implantable electrical devices offer a variety of potential diagnostic options and treatments in different medical fields. Especially in the absence of specific drugs, the implantable nerve electrodes...
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Inorganic-polymer composite coatings for biomedical devices
2021
Medical coatings are now playing key roles in the practical use of biomedical devices. By fabricating coatings, the biocompatibility of the devices would be significantly improved, and their biofunctions...
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Graphene oxide as a promising material in dentistry and tissue regeneration: A review
2021
Current treatments for common dental diseases such as caries, periodontal diseases, tooth defects, missing teeth and bone defects cannot replenish dental tissue with artificial alternatives while maintaining...
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Inorganic nano-carriers based smart drug delivery systems for tumor therapy
2020
Tumor is a severe disease that affects human health. In addition to surgical treatment and radiotherapy, applying therapeutic agents that can kill the tumor directly or regulate immune systems is one...
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Functionalization strategies of electrospun nanofibrous scaffolds for nerve tissue engineering
2021
Despite the high number of nerve injuries, there is a lack of an effective nerve repair strategy to restore nerve function. As crucial candidates for tissue engineering, electrospun nanofibrous scaffolds...
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High strength porous PLA gyroid scaffolds manufactured via fused deposition modeling for tissue-engineering applications
2021
Gyroid polylactic acid (PLA) scaffolds with different unit cell sizes of 2 mm (G2), 2.5 mm (G25), and 3 mm (G3) were fabricated via fused deposition modeling for bone tissue engineering applications....
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Biomaterial surface modification for underwater adhesion
2020
Biomaterial surfaces tend to adhere only under dry conditions, preventing them from being used in underwater environments such as body fluids. Therefore, biomaterial surfaces with underwater adhesion...
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Recent advances of emerging microfluidic chips for exosome mediated cancer diagnosis
2021
Recent technological advances in the field of microfluidic chips have provided great opportunities to boost the development of exosome-based cancer diagnosis. The emerging microfluidic chips with intrinsic...
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Antibacterial peptide-modified collagen nanosheet for infected wound repair
2021
Dressing materials with wet adhesive and antibacterial features are in high demand for the healing of infected wounds. Here, we report the development of an antibacterial peptide (KRWWKWWRRC)-modified...
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Self-assembling, self-adjuvanting and fully synthetic peptide nanovaccine for cancer immunotherapy
2021
Cancer vaccines designed to initiate or amplify tumor-specific T-cell responses have been used as a key approach for effective cancer immunotherapy. Across the history of tumor antigens, now we are...
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Biocompatible composite films and fibers based on Poly(Vinyl alcohol) and powders of calcium salts
2021
A method for obtaining composite biodegradable materials in the form of films and fibers, based on hydrophilic poly(vinyl alcohol) matrix and synthetic nanopowders of calcium salts containing phosphate...
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Near-infrared light-triggered nitric oxide release combined with low-temperature photothermal therapy for synergetic antibacterial and antifungal
2021
In recent years, nitric oxide (NO) has been widely studied as a non-drug resistant antimicrobial agent, but the issue of low NO loading capacity as well as premature leakage during transportation limit...
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Interactions between induced pluripotent stem cells and stem cell niche augment osteogenesis and bone regeneration
2021
Repair and reconstruction of critical-size bone defects have been challenges in the clinic for many years. Stem cell therapy is a promising strategy for these dilemmas, and induced pluripotent stem...
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Recent progress in the development of portable high voltage source based on triboelectric nanogenerator
2020
Triboelectric nanogenerators (TENGs), which can transfer surrounding environmental mechanical stimuli into electricity effectively, could be an ideal candidate as a sustainable power supply for electrical...
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Recent advances in surface manipulation using micro-contact printing for biomedical applications
2021
Surface properties are largely responsible for the biological performance of biomedical devices, suggesting the great necessity of surface modification. Micro-contact printing (μCP) is a versatile surface...
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Tissue-adhesive and highly mechanical double-network hydrogel for cryopreservation and sustained release of anti-cancer drugs
2021
Applications of hydrogels served as drug carriers are severely limited by several main drawbacks of instable network structure, weak mechanical strength, shortage of tissue-adhesive ability, as well...
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Recent advances in nano material-based application of liver neoplasms
2021
Significant impacts have occurred around the world because of liver neoplasms, especially Hepatocellular Carcinoma(HCC). Nano material has been used in diagnosis and treatment of liver neoplasms and...
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Mussel-inspired peptide mimicking: An emerging strategy for surface bioengineering of medical implants
2021
With the massive use of medical implants (e.g., metals, polymers and ceramics) in orthopedic and cardiovascular surgery, surface biomodification of these exogenous biomaterials has caused growing concern,...
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Nanoparticles breakthroughs tumor treatment limitations by regulating tumor immune microenvironment to enhance tumor immunotherapy efficacy
2021
After recent years of tumor treatment research, scientists gradually found that immunotherapy has the best application prospect among various treatment methods. Immunotherapy can be achieved through...
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Fluorinated hyaluronates endow oral nanoparticles with mucus penetration and colonic macrophage targeting properties
2021
The therapeutic outcomes of oral nanotherapeutics against ulcerative colitis (UC) are compromised by their shortage of mucus-penetrating and macrophage-targeting properties. Herein, hyaluronate (HA)...
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Poly(glyceryl sebacate)/silk fibroin small-diameter artificial blood vessels with good elasticity and compliance
2021
Small-diameter artificial blood vessels do not match the compliance of the host blood vessels after transplantation, will directly affect the blood compatibility of small-diameter artificial blood vessels...
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Simultaneous application of diamond-like carbon coating and surface amination on polyether ether ketone: Towards superior mechanical performance and osseointegration
2021
Poor osseointegration ability and the release of worn debris after implantation are the main issues impeding the clinic application of polyether ether ketone (PEEK) as orthopedics. To address these...
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Endoplasmic reticulum-targeting nanomedicines for cancer therapy
2021
In drug development research, the specific affinity of drug delivery systems for particular pathological sites, cells, and even subcellular structures can largely reduce the side effects, systemic toxicity,...
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