Bioactive carbon dots for tissue engineering applications
2024
Carbon dots (CDs) are carbon-based zero-dimensional nanomaterials with characteristic sizes of less than 10 nm. Recently, bioactive CDs have made remarkable achievements in wound healing, bone and...
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Real-time actuation of a dielectric elastomer actuator neuroprosthesis for facial paralysis
2024
Facial paralysis is a highly burdening condition, resulting in a patient's inability to move his mimic musculature on one or both sides of his face. This condition compromises the patient's communication...
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Magnetosurgery: Principles, design, and applications
2024
Magnetosurgery, the guidance or actuation of surgical instruments during operations using magnetic forces, has become a global trend in minimally invasive surgeries performed remotely. Despite the promise...
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Recent advances in three-dimensional printing in cardiovascular devices: Bench and bedside applications
2024
Three-dimensional (3D) printing is emerging as an innovative technology, which is widely used in cardiovascular disease at bench and bedside. During the last decade, with the development of 3D printing...
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Octopus -inspired gelatin-methacrylate scaffolds loaded with hBMSC-derived exosomes promote wound healing by regulating macrophage polarization
2024
Excessive local movement and inflammation are common problems in the process of wound repair, which lead to failure of later repair. In order to solve this problem, inspired by the octopus sucker structure,...
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The marine natural product trichobotrysin B inhibits proliferation and promotes apoptosis of human glioma cells via the IL-6-mediated STAT3/JAK signaling pathway
2024
Glioma is the most common malignant tumor of the central nervous system. Drug-assisted chemotherapy is an important adjuvant treatment post-surgery, but currently, effective chemotherapy drugs for glioma...
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Optical nanoprobes in biomedical diagnosis assays: Recent progress
2024
Biomedical assays based on optical nanoprobes play an important role in human health. Optical nanoprobes, the nanomaterials with special optical properties, are widely utilized in biomedical assays....
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Enhancing bone regeneration with a novel bioactive glass-functionalized polyetheretherketone scaffold by regulating the immune microenvironment
2024
Polyetheretherketone (PEEK) has become a promising material for bone engineering due to its excellent mechanical properties, radiolucency and chemical resistance. However, its inherent bioinertness...
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A detailed protocol for cell force measurement by traction force microscopy
2024
Cellular traction forces (CTFs) are generated by adherent cells and involved in regulating migration, morphology, and homeostasis. Accurate measurement of CTFs is crucial for understanding fundamental...
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Potentiating sorafenib efficacy against hepatocellular carcinoma via a carrier-free nanomedicine of artesunate prodrug
March 2024
Sorafenib is a first-line drug for liver cancer treatment, but its clinical efficacy is still limited by drawbacks such as drug tolerance, toxic effects, and low bioavailability. Therefore, it is urgent...
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Optimising degradation and mechanical performance of additively manufactured biodegradable Fe–Mn scaffolds using design strategies based on triply periodic minimal surfaces
March 2024
Additively manufactured lattices based on triply periodic minimal surfaces (TPMS) have attracted significant research interest from the medical industry due to their good mechanical and biomorphic properties....
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Smartphone-based polydiacetylene colorimetric sensor for point-of-care diagnosis of bacterial infections
March 2024
The rapid progress in point-of-care testing (POCT) has become a promising decentralized patient-centered approach for the control of infectious diseases, especially in resource-limited settings. POCT...
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Hydrogel wound dressings containing bioactive compounds originated from traditional Chinese herbs: A review
March 2024
Various factors can cause skin defects, resulting in the loss of physiological functions and even death due to severe concurrent infection. Dressings are often clinically used to fully cover the wounds...
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Biofabrication of natural Au/bacterial cellulose hydrogel for bone tissue regeneration via in-situ fermentation
2023
Bacterial cellulose (BC) possesses the desirable properties of biocompatibility, high porosity, high surface area and noticeable mechanical strength as a scaffold in bone tissue engineering. However,...
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Natural biopolyester microspheres with diverse structures and surface topologies as micro-devices for biomedical applications
2023
Based on their excellent biocompatibility and adjustable biodegradability, the two natural polyesters polylactic acid (PLA) and polyhydroxyalkanoates (PHAs) have been widely used in medical engineering...
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Antibacterial silk sericin/poly (vinyl alcohol) hydrogel with antifungal property for potential infected large burn wound healing: Systemic evaluation
2023
Hydrogel-based burn wound dressings with excellent antibacterial, antifungal, and mechanical properties are ideal biomaterials to promote infected large burn wound healing. In this study, the hydrogel...
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Application of nanomedicine and mesenchymal stem cells in burn injuries for the elderly patients
2023
Burns not only damage the skin barrier, but also cause a series of inflammatory reactions and oxidative stress states. Among them, elderly patients are prone to suffer severe burns due to degenerative...
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A responsive hydrogel-based microneedle system for minimally invasive glucose monitoring
2023
Blood glucose (BG) monitoring in patients with diabetes is critical for diabetes management. Minimally invasive BG monitoring is urgently required to increase the patient compliance. Herein, based on...
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Core-shell nanostructures for improving dental restorative materials: A scoping review of composition, methods, and outcome
2023
Dental resin adhesives and composites are the most prevailing dental restorative materials used to treat cavitated tooth decay. These materials are challenged inside the mouth by bacterial acid attack,...
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Optical biosensors for diabetes management: Advancing into stimuli-responsive sensing mechanisms
2023
Diabetes is one of the most common chronic diseases that contribute significantly to global mortality. Effective glucose-sensing platforms might allow for an improved monitoring of disease progression,...
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Promotion of wound healing by a thermosensitive and sprayable hydrogel with nanozyme activity and anti-inflammatory properties
2023
The rapid healing of wounds requires strategies that relieve oxidative stress resulting from overloaded free radicals and which promote angiogenesis, collagen deposition, and re-epithelialization of...
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Function and treatment strategies of β-hydroxybutyrate in aging
2023
Metabolic intermediates serve as precursors for bioactive molecule synthesis, the energy source for life activities, and signals for environmental adaptation. Ketone bodies are important metabolic intermediates...
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Epidermal growth factor-loaded microspheres/hydrogel composite for instant hemostasis and liver regeneration
2023
Rapid hemostasis and effective healing for the non-compressible liver wounds which are not able to be sewn, especially for those large-area wounds, remain great clinical challenges. In this study, we...
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Nanotherapies from an oncologist doctor's view
2023
Cancer remains the leading cause of death and an important barrier to increase life expectancy. It is desirable to develop therapeutics that can improve life quality and prolong the survival duration....
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A pH/temperature responsive nanocomposite for chemo-photothermal synergistic cancer therapy
2023
To optimize synergistic breast cancer treatment, a nanocomposite was fabricated with pH-temperature responsive and chemo-photothermal combination therapy. Herein, gold nanorods (AuNRs) are coated with...
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