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ISSN: 2590-1834

3D-printed bioactive scaffolds for bone regeneration bearing carbon dots for bioimaging purposes

Additive manufacturing, also known as 3D-printing, has been successfully employed to create novel bioactive scaffolds incorporating carbon dots for bioimaging purposes. Fused filament fabrication technique...

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Twisted fiber batteries for wearable electronic devices

Wearable electronic devices are important in recording signals related to human activities. Because the performance of wearable electronic devices depends heavily on power sources, batteries, especially...

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Signaling pathways implicated in enhanced stem/progenitor cell differentiation on electroactive scaffolds

Cells are naturally surrounded by an electroactive extracellular matrix in vivo, which is composed of a diverse array of charged molecules such as glycosaminoglycans and proteoglycans, together with...

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Recent advances in orthopedic polyetheretherketone biomaterials: Material fabrication and biofunction establishment

Polyetheretherketone (PEEK) is a kind of nontoxic high-performance thermoplastic widely used for medical applications. Compared with other special engineering plastics, PEEK has many excellent properties,...

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Bio-macromolecules/modified-halloysite composite hydrogel used as multi-functional wound dressing

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Designing HA/PEI nanoparticle composite coating on biodegradable Mg–Zn–Y-Nd alloy to direct cardiovascular cells fate

Biodegradable magnesium (Mg) alloy as a new generation of cardiovascular stent material has attracted great attention. However, the problems of excessive degradability and lack of corresponding biological...

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Cellularized polymeric microarchitectures for drug screening

Despite the enormous applicability, the traditional, oversimplified in vitro two-dimensional (2D) monolayer cell culture models for preclinical drug screening towards evaluating pharmacological as well...

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Sonodynamic therapy: Another “light” in tumor treatment by exogenous stimulus

Reactive oxygen species (ROS) have been proven to be tightly related to multiple cell functions, such as proliferation, differentiation and apoptosis. Excessive accumulation of ROS above a certain threshold...

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Mussel-inspired peptide mimicking: An emerging strategy for surface bioengineering of medical implants

With the massive use of medical implants (e.g., metals, polymers and ceramics) in orthopedic and cardiovascular surgery, surface biomodification of these exogenous biomaterials has caused growing concern,...

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Controllable preparation of (200) facets preferential oriented silver nanowires for non-invasive detection of glucose in human sweat

(200) facets preferential oriented Ag nanowires were controllably prepared by a simple modified one-step polyol method, in which Cl ions and polyvinyl pyrrolidone (PVP) were employed as nucleating agent...

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Functionalization strategies of electrospun nanofibrous scaffolds for nerve tissue engineering

Despite the high number of nerve injuries, there is a lack of an effective nerve repair strategy to restore nerve function. As crucial candidates for tissue engineering, electrospun nanofibrous scaffolds...

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Near-infrared light-triggered nitric oxide release combined with low-temperature photothermal therapy for synergetic antibacterial and antifungal

In recent years, nitric oxide (NO) has been widely studied as a non-drug resistant antimicrobial agent, but the issue of low NO loading capacity as well as premature leakage during transportation limit...

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Inorganic-polymer composite coatings for biomedical devices

Medical coatings are now playing key roles in the practical use of biomedical devices. By fabricating coatings, the biocompatibility of the devices would be significantly improved, and their biofunctions...

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Fmoc-amino acid-based hydrogel vehicle for delivery of amygdalin to perform neuroprotection

Amygdalin is widely distributed in the plant kingdom. Oral delivery of amygdalin releases hydrogen cyanide upon endogenous enzymes causing potential toxic effects to humans. Here, we fabricate Fmoc-Tyr–OH–amygdalin...

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Recent advances in surface manipulation using micro-contact printing for biomedical applications

Surface properties are largely responsible for the biological performance of biomedical devices, suggesting the great necessity of surface modification. Micro-contact printing (μCP) is a versatile surface...

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Ultra-transparent slippery surface

Endoscopes are used for diagnosis and minimally invasive treatment of the interior regions of the body. The visual fields of endoscopes, especially angioscopes, are often obscured due to the contamination...

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Recent advances in nano material-based application of liver neoplasms

Significant impacts have occurred around the world because of liver neoplasms, especially Hepatocellular Carcinoma(HCC). Nano material has been used in diagnosis and treatment of liver neoplasms and...

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Photonic crystal barcode: An emerging tool for cancer diagnosis

Photonic crystal barcodes, as one of the most powerful and stable coding methods among encoded carriers, have achieved significant success in mimetic multiplex detection of various cancer biomarkers...

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Self-assembling, self-adjuvanting and fully synthetic peptide nanovaccine for cancer immunotherapy

Cancer vaccines designed to initiate or amplify tumor-specific T-cell responses have been used as a key approach for effective cancer immunotherapy. Across the history of tumor antigens, now we are...

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Tissue-adhesive and highly mechanical double-network hydrogel for cryopreservation and sustained release of anti-cancer drugs

Applications of hydrogels served as drug carriers are severely limited by several main drawbacks of instable network structure, weak mechanical strength, shortage of tissue-adhesive ability, as well...

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Fluorinated hyaluronates endow oral nanoparticles with mucus penetration and colonic macrophage targeting properties

The therapeutic outcomes of oral nanotherapeutics against ulcerative colitis (UC) are compromised by their shortage of mucus-penetrating and macrophage-targeting properties. Herein, hyaluronate (HA)...

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Graphene oxide as a promising material in dentistry and tissue regeneration: A review

Current treatments for common dental diseases such as caries, periodontal diseases, tooth defects, missing teeth and bone defects cannot replenish dental tissue with artificial alternatives while maintaining...

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Smart and in-situ formation electrospun fibrous membrane for the control of antimicrobial efficacy

A smart poly(N-isopropyl acrylamide- N-Methylol acrylamide-acrylic acid) (PNIPAm-NMA-Ac) fibrous membrane with a dual response to thermal and pH was obtained via radical copolymerization and electrospinning...

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High strength porous PLA gyroid scaffolds manufactured via fused deposition modeling for tissue-engineering applications

Gyroid polylactic acid (PLA) scaffolds with different unit cell sizes of 2 ​mm (G2), 2.5 ​mm (G25), and 3 ​mm (G3) were fabricated via fused deposition modeling for bone tissue engineering applications....

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Core/shell structural ultra-small gold and amyloid peptide nanocomposites with effective bacterial surface adherence and enhanced antibacterial photothermal ablation

The exploration of ultra-small gold nanoparticles (Au NPs) (<5 ​nm) based photothermal nanoagent is important for antibacterial photothermal therapy due to their high biosafety. However, the ultra-small...

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