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ISSN: 2590-1834

Biofabrication of natural Au/bacterial cellulose hydrogel for bone tissue regeneration via in-situ fermentation

Bacterial cellulose (BC) possesses the desirable properties of biocompatibility, high porosity, high surface area and noticeable mechanical strength as a scaffold in bone tissue engineering. However,...

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Natural biopolyester microspheres with diverse structures and surface topologies as micro-devices for biomedical applications

Based on their excellent biocompatibility and adjustable biodegradability, the two natural polyesters polylactic acid (PLA) and polyhydroxyalkanoates (PHAs) have been widely used in medical engineering...

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Antibacterial silk sericin/poly (vinyl alcohol) hydrogel with antifungal property for potential infected large burn wound healing: Systemic evaluation

Hydrogel-based burn wound dressings with excellent antibacterial, antifungal, and mechanical properties are ideal biomaterials to promote infected large burn wound healing. In this study, the hydrogel...

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Recent advances in hyaluronic acid-based hydrogels for 3D bioprinting in tissue engineering applications

3D bioprinting technology can rapidly process cell-loaded biomaterials to prepare personalized scaffolds for repairing defective tissues, tissue regeneration, and even printing tissues or organs. 3D...

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Developments of microfluidics for orthopedic applications: A review

With the development of modern medicine, the research methods of occurrence, development and treatment of orthopedic diseases are developing rapidly. The microenvironment provided by traditional orthopedic...

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Application of nanomedicine and mesenchymal stem cells in burn injuries for the elderly patients

Burns not only damage the skin barrier, but also cause a series of inflammatory reactions and oxidative stress states. Among them, elderly patients are prone to suffer severe burns due to degenerative...

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A responsive hydrogel-based microneedle system for minimally invasive glucose monitoring

Blood glucose (BG) monitoring in patients with diabetes is critical for diabetes management. Minimally invasive BG monitoring is urgently required to increase the patient compliance. Herein, based on...

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Core-shell nanostructures for improving dental restorative materials: A scoping review of composition, methods, and outcome

Dental resin adhesives and composites are the most prevailing dental restorative materials used to treat cavitated tooth decay. These materials are challenged inside the mouth by bacterial acid attack,...

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Optical biosensors for diabetes management: Advancing into stimuli-responsive sensing mechanisms

Diabetes is one of the most common chronic diseases that contribute significantly to global mortality. Effective glucose-sensing platforms might allow for an improved monitoring of disease progression,...

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Promotion of wound healing by a thermosensitive and sprayable hydrogel with nanozyme activity and anti-inflammatory properties

The rapid healing of wounds requires strategies that relieve oxidative stress resulting from overloaded free radicals and which promote angiogenesis, collagen deposition, and re-epithelialization of...

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A study involving PC-3 cancer cells and novel carbamate gemini surfactants: Is zeta potential the key to control adhesion to cells?

Liposome surface potential effect on cellular uptake and cytotoxicity is evaluated using liposomes, modified with cationic lipid DOTAP, a series of cationic gemini surfactants with two carbamate fragments,...

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Towards clinical translation of the cell sheet engineering: Technological aspects

Cell sheet engineering is a rapidly growing field of tissue engineering and regenerative medicine. The ease of cell sheet obtainment techniques and the resulting unique characteristics and microenvironment...

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Function and treatment strategies of β-hydroxybutyrate in aging

Metabolic intermediates serve as precursors for bioactive molecule synthesis, the energy source for life activities, and signals for environmental adaptation. Ketone bodies are important metabolic intermediates...

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Epidermal growth factor-loaded microspheres/hydrogel composite for instant hemostasis and liver regeneration

Rapid hemostasis and effective healing for the non-compressible liver wounds which are not able to be sewn, especially for those large-area wounds, remain great clinical challenges. In this study, we...

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Nanotherapies from an oncologist doctor's view

Cancer remains the leading cause of death and an important barrier to increase life expectancy. It is desirable to develop therapeutics that can improve life quality and prolong the survival duration....

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A pH/temperature responsive nanocomposite for chemo-photothermal synergistic cancer therapy

To optimize synergistic breast cancer treatment, a nanocomposite was fabricated with pH-temperature responsive and chemo-photothermal combination therapy. Herein, gold nanorods (AuNRs) are coated with...

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Biosensor-based therapy powered by synthetic biology

The study of synthetic biology focusing on biosensor systems has resulted from a growing interest in developing customized biological devices with desired cellular functions. Recently, biosensors have...

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Journey of smart material from composite to shape memory alloy (SMA), characterization and their applications-A review

This review paper deals with the advancements of composites to shape memory alloys. The journey of smart materials from conventional composites to advance shape memory alloys and their application is...

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Design of 3D smart scaffolds using natural, synthetic and hybrid derived polymers for skin regenerative applications

Effective wound care is a major concern as many conventional wound healing methods and materials have failed in facilitating proper healing, instead disrupts the overall healing process, leading to...

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Advances in mRNA nanomedicines for malignant brain tumor therapy

Nowadays, malignant brain tumors are still mostly lethal diseases with poor prognosis and a clinical median survival rate of fewer than 2 years after therapeutic intervention. It is difficult to achieve...

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Tailoring the elasticity of nerve implants for regulating peripheral nerve regeneration

Numerous studies have conducted in-depth research on the biological and chemical properties of tissue-engineered neural graft (TENG) on peripheral nerve regeneration, while the physical properties of...

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Tumor microenvironment-responsive Zn/Cu nanoparticles for enhanced chemodynamic therapy

Chemodynamic therapy (CDT) has emerged as an effective and safe anticancer therapeutic strategy by catalytic generation of hydroxyl radicals via Fenton chemistry to kill notorious cancer cells. Herein,...

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The versatile applications of polydopamine in regenerative medicine: Progress and challenges

In recent decades, great progress has been made in regenerative medicine with the development of various functional scaffolds, many of which have been put into practical clinical applications. In this...

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Metallic nanoscale-knife application in cancer theranostics

Nanoscale metal is considered the backbone of biomedical nanotechnology. Recently, there has been an exponential increase in nanoscale materials’ biomedical applications. These nanomaterials have mainly...

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Emerging polymeric biomaterials and manufacturing-based tissue engineering approaches for neuro regeneration-A critical review on recent effective approaches

The nervous system is a crucial part of the human body that is damaged by traumatic injury, stroke, and neurodegenerative diseases. Recent studies also have shown that neurodegenerative diseases are...

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