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ISSN: 2590-1834

Promotion of wound healing by a thermosensitive and sprayable hydrogel with nanozyme activity and anti-inflammatory properties

The rapid healing of wounds requires strategies that relieve oxidative stress resulting from overloaded free radicals and which promote angiogenesis, collagen deposition, and re-epithelialization of...

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Function and treatment strategies of β-hydroxybutyrate in aging

Metabolic intermediates serve as precursors for bioactive molecule synthesis, the energy source for life activities, and signals for environmental adaptation. Ketone bodies are important metabolic intermediates...

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Epidermal growth factor-loaded microspheres/hydrogel composite for instant hemostasis and liver regeneration

Rapid hemostasis and effective healing for the non-compressible liver wounds which are not able to be sewn, especially for those large-area wounds, remain great clinical challenges. In this study, we...

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Nanotherapies from an oncologist doctor's view

Cancer remains the leading cause of death and an important barrier to increase life expectancy. It is desirable to develop therapeutics that can improve life quality and prolong the survival duration....

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A pH/temperature responsive nanocomposite for chemo-photothermal synergistic cancer therapy

To optimize synergistic breast cancer treatment, a nanocomposite was fabricated with pH-temperature responsive and chemo-photothermal combination therapy. Herein, gold nanorods (AuNRs) are coated with...

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Biosensor-based therapy powered by synthetic biology

The study of synthetic biology focusing on biosensor systems has resulted from a growing interest in developing customized biological devices with desired cellular functions. Recently, biosensors have...

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Journey of smart material from composite to shape memory alloy (SMA), characterization and their applications-A review

This review paper deals with the advancements of composites to shape memory alloys. The journey of smart materials from conventional composites to advance shape memory alloys and their application is...

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Tailoring the elasticity of nerve implants for regulating peripheral nerve regeneration

Numerous studies have conducted in-depth research on the biological and chemical properties of tissue-engineered neural graft (TENG) on peripheral nerve regeneration, while the physical properties of...

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Metallic nanoscale-knife application in cancer theranostics

Nanoscale metal is considered the backbone of biomedical nanotechnology. Recently, there has been an exponential increase in nanoscale materials’ biomedical applications. These nanomaterials have mainly...

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Research hotspots and trends of biodegradable magnesium and its alloys

With the increasing demand for innovative therapies, biodegradable magnesium has attracted more and more attention, which could avoid secondary surgery and reduce complications. Until now, plenty of...

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Anti-inflammatory, antibacterial, and antioxidative bioactive glass-based nanofibrous dressing enables scarless wound healing

Excessive scar tissue formation along with bacterial infection, hemorrhage, and oxidative wound microenvironment pose adverse physiological and psychological effects on patients, which necessitate the...

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Reactive oxygen species-sensitive materials: A promising strategy for regulating inflammation and favoring tissue regeneration

Reactive oxygen species (ROS), acting as essential mediators in the biological system, highly influence the physiologic and pathologic processes of the human body. The aberrant production of ROS, caused...

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Silk sericin-based biomaterials shine in food and pharmaceutical industries

Silk sericin (SS) is a byproduct of the silk production process that consists of 18 ​amino acids and numerous polar groups. SS has a range of unique physical, chemical, and biological properties, such...

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Phospholipid-based nanodrill technology for enhanced intracellular delivery of nano-sized cargos

Nanosized drug delivery systems typically enter the cell via endocytosis. However, a significant amount of the endocytosed cargo cannot effectively escape from the endosome, resulting in drug degradation....

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Tube-shaped nanostructures for enhancing resin-based dental materials: A landscape of evidence and research advancement

With the advent of nanotechnology, incorporating nanoscale fillers in dental resins seems promising to improve therapeutic features and provide more excellent physicochemical properties for dental materials....

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In situ electrospun aloe-nanofiber membrane for chronic wound healing

Alleviating excessive inflammation while accelerating chronic wound healing to prevent wound infection has remained challenging, especially during the coronavirus disease 2019 (COVID-19) pandemic caused...

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The role of exosomes in regulation and application of vascular homeostasis and vascular grafts

The global morbidity and mortality of cardiovascular diseases are increasing yearly, among which vascular diseases are the main cause of death. Traditional drugs have multiple limitations in the treatment...

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Immunomodulation-based development engineering for advancing metal soft tissue implants

Metal materials have been widely applied clinically due to their superior mechanical properties. However, the integration of metallic implants with surrounding soft tissue remains challenging and may...

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Chitosan-calcium carbonate scaffold with high mineral content and hierarchical structure for bone regeneration

Bone regeneration scaffolds loaded with osteoblast-related cells or cytokines exhibit outstanding therapeutic potential during large-scale bone defect repair. However, limited sources of cells, opportune...

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Structurally optimized electrospun scaffold for biomaterial-controlled synergistic enhancement of defective bone healing

Bone repair processes are tightly affected by fiber topographies of scaffolds and can be promoted by coupling with chemotactic and/or angiogenic molecules. Here, we developed polycaprolactone (PCL)...

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Platinum nanoparticles enhance osteogenic differentiation of human dental follicle stem cells via scavenging ROS

The over-accumulation of ROS during prolonged in vitro expansion could negatively affect the properties of stem cells. This leads to a reduced capacity for self-renewal and a lower potential for multiple...

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Circulating exosomes in sepsis: A potential role as diagnostic biomarkers, therapeutic and drug delivery carriers

Sepsis and sepsis-related organ dysfunction have been identified as significant global life-threatening health threats, with a high mortality rate despite ongoing research in the area. Timely diagnosis...

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Promotion of osteoporotic bone healing by a tannic acid modified strontium-doped biomimetic bone lamella with ROS scavenging capacity and pro-osteogenic effect

The impaired osteogenic ability and excessive accumulation of reactive oxygen species (ROS) under osteoporosis severely weaken repair performance of biomimetic bone grafts. Currently, biomimetic bone...

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Eggshell-derived amorphous calcium phosphate: Synthesis, characterization and bio-functions as bone graft materials in novel 3D osteoblastic spheroids model

A multitude of autogenous/allogeneic and semi-synthetic bone graft materials have been developed to reconstruct the defective bone tissue but with high bio-cost and potential environmental pollution....

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