Hydrogel wound dressings containing bioactive compounds originated from traditional Chinese herbs: A review
March 2024
Various factors can cause skin defects, resulting in the loss of physiological functions and even death due to severe concurrent infection. Dressings are often clinically used to fully cover the wounds...
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Octopus -inspired gelatin-methacrylate scaffolds loaded with hBMSC-derived exosomes promote wound healing by regulating macrophage polarization
March 2024
Excessive local movement and inflammation are common problems in the process of wound repair, which lead to failure of later repair. In order to solve this problem, inspired by the octopus sucker structure,...
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Phospholipid-based nanodrill technology for enhanced intracellular delivery of nano-sized cargos
2023
Nanosized drug delivery systems typically enter the cell via endocytosis. However, a significant amount of the endocytosed cargo cannot effectively escape from the endosome, resulting in drug degradation....
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Tube-shaped nanostructures for enhancing resin-based dental materials: A landscape of evidence and research advancement
2023
With the advent of nanotechnology, incorporating nanoscale fillers in dental resins seems promising to improve therapeutic features and provide more excellent physicochemical properties for dental materials....
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In situ electrospun aloe-nanofiber membrane for chronic wound healing
2023
Alleviating excessive inflammation while accelerating chronic wound healing to prevent wound infection has remained challenging, especially during the coronavirus disease 2019 (COVID-19) pandemic caused...
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Structurally optimized electrospun scaffold for biomaterial-controlled synergistic enhancement of defective bone healing
2023
Bone repair processes are tightly affected by fiber topographies of scaffolds and can be promoted by coupling with chemotactic and/or angiogenic molecules. Here, we developed polycaprolactone (PCL)...
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Biofabrication of natural Au/bacterial cellulose hydrogel for bone tissue regeneration via in-situ fermentation
2023
Bacterial cellulose (BC) possesses the desirable properties of biocompatibility, high porosity, high surface area and noticeable mechanical strength as a scaffold in bone tissue engineering. However,...
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Core-shell nanostructures for improving dental restorative materials: A scoping review of composition, methods, and outcome
2023
Dental resin adhesives and composites are the most prevailing dental restorative materials used to treat cavitated tooth decay. These materials are challenged inside the mouth by bacterial acid attack,...
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Promotion of wound healing by a thermosensitive and sprayable hydrogel with nanozyme activity and anti-inflammatory properties
2023
The rapid healing of wounds requires strategies that relieve oxidative stress resulting from overloaded free radicals and which promote angiogenesis, collagen deposition, and re-epithelialization of...
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Immunomodulation-based development engineering for advancing metal soft tissue implants
2023
Metal materials have been widely applied clinically due to their superior mechanical properties. However, the integration of metallic implants with surrounding soft tissue remains challenging and may...
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Natural biopolyester microspheres with diverse structures and surface topologies as micro-devices for biomedical applications
2023
Based on their excellent biocompatibility and adjustable biodegradability, the two natural polyesters polylactic acid (PLA) and polyhydroxyalkanoates (PHAs) have been widely used in medical engineering...
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A responsive hydrogel-based microneedle system for minimally invasive glucose monitoring
2023
Blood glucose (BG) monitoring in patients with diabetes is critical for diabetes management. Minimally invasive BG monitoring is urgently required to increase the patient compliance. Herein, based on...
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Optical biosensors for diabetes management: Advancing into stimuli-responsive sensing mechanisms
2023
Diabetes is one of the most common chronic diseases that contribute significantly to global mortality. Effective glucose-sensing platforms might allow for an improved monitoring of disease progression,...
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Silk sericin-based biomaterials shine in food and pharmaceutical industries
2023
Silk sericin (SS) is a byproduct of the silk production process that consists of 18 amino acids and numerous polar groups. SS has a range of unique physical, chemical, and biological properties, such...
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Antibacterial silk sericin/poly (vinyl alcohol) hydrogel with antifungal property for potential infected large burn wound healing: Systemic evaluation
2023
Hydrogel-based burn wound dressings with excellent antibacterial, antifungal, and mechanical properties are ideal biomaterials to promote infected large burn wound healing. In this study, the hydrogel...
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Tailoring the elasticity of nerve implants for regulating peripheral nerve regeneration
2023
Numerous studies have conducted in-depth research on the biological and chemical properties of tissue-engineered neural graft (TENG) on peripheral nerve regeneration, while the physical properties of...
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Nanotherapies from an oncologist doctor's view
2023
Cancer remains the leading cause of death and an important barrier to increase life expectancy. It is desirable to develop therapeutics that can improve life quality and prolong the survival duration....
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Epidermal growth factor-loaded microspheres/hydrogel composite for instant hemostasis and liver regeneration
2023
Rapid hemostasis and effective healing for the non-compressible liver wounds which are not able to be sewn, especially for those large-area wounds, remain great clinical challenges. In this study, we...
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Platinum nanoparticles enhance osteogenic differentiation of human dental follicle stem cells via scavenging ROS
2023
The over-accumulation of ROS during prolonged in vitro expansion could negatively affect the properties of stem cells. This leads to a reduced capacity for self-renewal and a lower potential for multiple...
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Application of nanomedicine and mesenchymal stem cells in burn injuries for the elderly patients
2023
Burns not only damage the skin barrier, but also cause a series of inflammatory reactions and oxidative stress states. Among them, elderly patients are prone to suffer severe burns due to degenerative...
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Anti-inflammatory, antibacterial, and antioxidative bioactive glass-based nanofibrous dressing enables scarless wound healing
2023
Excessive scar tissue formation along with bacterial infection, hemorrhage, and oxidative wound microenvironment pose adverse physiological and psychological effects on patients, which necessitate the...
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Research hotspots and trends of biodegradable magnesium and its alloys
2023
With the increasing demand for innovative therapies, biodegradable magnesium has attracted more and more attention, which could avoid secondary surgery and reduce complications. Until now, plenty of...
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Journey of smart material from composite to shape memory alloy (SMA), characterization and their applications-A review
2023
This review paper deals with the advancements of composites to shape memory alloys. The journey of smart materials from conventional composites to advance shape memory alloys and their application is...
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Function and treatment strategies of β-hydroxybutyrate in aging
2023
Metabolic intermediates serve as precursors for bioactive molecule synthesis, the energy source for life activities, and signals for environmental adaptation. Ketone bodies are important metabolic intermediates...
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