Ruminal microbiota-derived inosine alleviates metabolic disorders in dairy cows supplemented with grape seed extract
December 2025
Ruminal microbiota and their metabolites can shape host metabolic responses. Grape seed extract (GSE) can modulate ruminal microbiota profiles and metabolites in vitro, thus, underscoring their potential...
Supplementation with Lycium barbarum byproducts improves energy and nitrogen metabolism, and reduces methane emissions in sheep grazing alfalfa/tall fescue pastures
Available online 6 October 2025
Functional native herbage (FNH), rich in bioactive components and secondary metabolites, holds potential for enhancing the productivity of grazing livestock and mitigating methane emissions. The processing...
Impacts of Andrographis paniculata supplementation on health and productivity in monogastric farm animals: A comprehensive review
Available online 6 October 2025
Growing concerns about antibiotic resistance and the pursuit for natural alternatives in animal production have driven the search for dietary additives that promote health and sustainability, without...
Evaluating soybean protein concentrate hydrolysate as a fishmeal substitute in the diet for mandarin fish (Siniperca chuatsi): Based on growth, intestinal health, flesh quality and nutrient metabolism
Available online 6 October 2025
The present experiment investigated the effects of soybean protein concentrated hydrolysate (SPCH) replacing fishmeal (FM) on the growth performance, intestinal health, flesh quality and nutrient metabolism...
Multi-omics analysis reveals the mechanism of rosemary extract supplementation in increasing milk production in Sanhe dairy cows via the “rumen-serum-milk” metabolic pathway
Available online 6 October 2025
Rosemary extract (RE) has shown potential as a plant-derived feed additive, but its effects on Sanhe dairy cows are still unknown. In this study, 30 multiparous Sanhe dairy cows (days in milk 171 ±...
Folic acid improves intestinal function in grass carp (Ctenopharyngodon idella): Revealing a new perspective of DNA methyltransferases and PP2A-p38 signaling pathway in intestinal epithelial function
Available online 6 October 2025
The beneficial effects of folic acid (FA) on intestinal barrier function are well recognized, however the underlying molecular mechanisms remain largely unexplored. This study aimed to investigate the...
Increased maternal valine intake in low-protein diets accelerates growth performance of suckling piglets by improving mammary gland - fetal intestinal metabolism
Available online 1 October 2025
Low-protein (LP) diets are increasingly recognized as a cost-effective and efficient strategy in the global livestock industry. Although previous studies have demonstrated that increased valine intake...
Dietary fiber derived short-chain fatty acids as a critical driver of the gut–bone axis in animal bone health: A review
September 2025
Intestinal health, regulated by gut microbiota, is essential for optimal animal production performance and bone metabolism. Dietary fiber, a key modulator of gut microbiota, influences microbial composition...
Enhancing milk quality and modulating plasma lipid metabolism of lactating dairy goats: The impact of bile acid supplementation
September 2025
An essential function carried out by bile acids (BA) is to aid in lipid absorption, as they emulsify lipids and combine with them to form chylomicrons. While BA have been utilized as lipid emulsifiers...
Insect fat as feed: Potential to modify the fatty acid composition of animal-derived foods
September 2025
Insect products are attracting both scientific and commercial interest because of their high quality as food and feed, with insect farming having a low environmental impact and the potential to mitigate...
4-Methylesculetin alleviated aflatoxin B1-induced liver injury and ferritinophagy through AMPK- TOR-Ulk axis in grass carp (Ctenopharyngodon idella)
September 2025
The mycotoxin aflatoxin B1 (AFB1), frequently identified in animal feed and raw materials, induces oxidative stress as a primary toxicological consequence. The coumarin compound 4-methylesculetin (4-ME)...
Unlocking the potential: Exploring the application of bioactive peptides in aquaculture
September 2025
Bioactive peptides (BAPs), typically comprising two to 20 amino acids, are widely acknowledged for their distinctive biological functions. They can be broadly classified as endogenous or exogenous peptides....
Understanding the differences in rumen bacteria and their impact on dairy cows’ production performance: A review
September 2025
This review aimed to summarize the relationship between rumen bacteria and production performance in dairy cows. The composition and metabolic functions of rumen bacteria significantly influenced production...
Indole-3-propionic acid enhances glycolytic myofiber formation in piglets through PI3K-mTOR activation and gut microbiota-driven tryptophan metabolic alteration
September 2025
Indole-3-propionic acid (IPA) is a metabolite of tryptophan produced by gut bacterial catabolism that has a variety of functions, including anti-inflammatory, free radical scavenging, and regulation...
Parathyroid glands exhibit reduced parenchymatic chief cells and increased extracellular collagen as a response to a long-term low-phosphorus diet in pigs
September 2025
Parathyroid glands (PTG) are essential in maintaining mineral homeostasis, particularly in regulating blood calcium (Ca) and phosphorus (P) levels. The endocrine regulation via parathyroid hormone (PTH)...
Methionine metabolism, functions, and application in swine
September 2025
Methionine (Met) is the only sulfur-containing essential amino acid for animals and is the second or third limiting amino acid in swine diets. It plays a role not only in protein synthesis, but also...
Methanotroph (Methylococcus capsulatus) bacteria meal, influences the intestinal microbiome, and improves intestinal barrier function and immunity in hybrid grouper (Epinephelus fuscointestinetatus ♀ × E. lanceolatus ♂)
September 2025
The hybrid grouper (Epinephelus fuscointestinetatus ♀ × E. lanceolatus ♂) is an important aquaculture marine species in China. The current study was designed to test the effects of methanotroph (Methylococcus...
Attrition of amino acids in the life span of broiler chickens
September 2025
A dietary protein intake of approximately 2.5 kg is required to generate 1.0 kg of protein in the carcass of broiler chickens at 42 d post–hatch, reflecting the attrition or wastage of dietary amino...
Effects of 25-hydroxyvitamin D3, chondroitin sulfate and glucosamine sulfate on the growth performance, calcium and phosphorus metabolism, and bone development of weaned piglets
September 2025
This study aimed to determine the effects of 25-hydroxyvitamin D3 (25-OH-VD3), combined with chondroitin sulfate (CS) and glucosamine sulfate (GS), on calcium and phosphorus metabolism and bone development...
Differential lipid metabolism in beef cattle: A comparative study of high and low residual feed intake bulls
September 2025
This study investigated lipid metabolism differences between low and high residual feed intake (LRFI and HRFI) bulls. Fifty-five Simmental bulls (449.84 ± 8.49 kg) were fed the same diet for 161 d to...
Investigation on the action mechanisms of taurine on rumen microbial crude protein synthesis and nitrogen metabolism in beef steers using sodium sulfate as a contrast
September 2025
Taurine is a sulfur-containing nonproteinogenic amino acid. Recent studies have shown that taurine can improve rumen microbial crude protein (MCP) synthesis. This experiment aimed to investigate the...
Benzoic acid—the cornerstone of any swine nutrition program
September 2025
Benzoic acid (BA) is an organic acid that has become a key dietary supplement in swine production, offering a comprehensive approach to improving gut health and performance while addressing challenges...
Vitamin E inhibits inflammation and improves immune response of mud crabs (Scylla paramamosain) by activating an antioxidant enzyme system and apoptosis mechanism
September 2025
An 8-week feeding trial was conducted to evaluate the effects of dietary vitamin E levels on growth, antioxidant status and immune response for mud crabs (Scylla paramamosain). A total of 180 mud crabs...
Increasing dietary indigestible protein may exacerbate coccidiosis in broiler chickens
September 2025
The objective was to determine whether increasing dietary indigestible protein concentration exacerbates detrimental effects of coccidiosis in broiler chickens. A total of 192 male broiler chickens...
Exogenous protease supplementation in high- and low-fishmeal diets for Pacific white shrimp (Penaeus vannamei): Comparative effect on growth, immunity, nutrient digestibility and gut health
September 2025
The present study evaluated the effects of exogenous protease supplementation in low- and high-fishmeal (FM) diets on growth performance, feed utilization, innate immunity, digestive enzyme activity,...