Transcriptomic analysis reveals the immunomodulatory role of Clostridium autoethanogenum protein on Litopenaeus vannamei under variable salinity conditions
December 2025
Salinity is a critical environmental factor in aquaculture, and Clostridium autoethanogenum protein (CAP) shows potential as a new feed protein source. This 8-week study compared two diets (fish meal...
Lactobacillus strains from sows improve swine appetite by reducing the pro-inflammatory cytokine concentrations
December 2025
Lactational feed intake (LFI) is important for the efficiency of sow production. Previous studies indicated that the gut microbiota participated in host appetite regulation. The role of the gut microbiota,...
New insights into methionine’s role in maintaining intestinal stem cell regeneration via autophagy regulation
December 2025
As an essential amino acid, methionine (Met) is crucial for several biological functions, including protein synthesis, cell proliferation, and protection against oxidative stress. As research uncovers...
Increasing carbohydrates or nitrogenous compounds by cecal infusion leads to an opposite influence on colonic microbiota and host metabolism in a pig model
December 2025
Gut microbes, particularly those in the hindgut, play an important role in fermenting undigested nutrients (carbohydrates and proteins) and in regulating host metabolism via the gut-liver metabolic...
Replacing fishmeal with composite plant protein meal affects nutrient metabolism via mTOR signaling pathway of Pacific white shrimp (Litopenaeus vannamei)
December 2025
This study evaluated the effects of a fishmeal-reduced diet containing a composite plant protein meal (soybean meal:peanut meal:gluten meal ratio = 20:10:3) on growth performance, metabolic homeostasis,...
Effects of coarse corn or oat hulls on growth performance, intestinal health, and microbiota modulation in underperforming broilers
December 2025
Intra-flock body weight (BW) variability in broilers increases production costs, as underperforming chicks often show suboptimal gut development and performance. Increasing grain particle size and dietary...
Terpine-4-ol alleviates lipopolysaccharide-induced intestinal injury in weaned piglets by regulating intestinal epithelial cell homeostasis via the Wnt/β-catenin signaling pathway
December 2025
This study aims to elucidate intestinal injury from the perspective of intestinal epithelial cell homeostasis and to explore the modulatory roles of terpine-4-ol (a major bioactive component of tea...
Novel insights into choline's role in promoting myofiber hypertrophy and mitochondrial function in muscle of sub-adult grass carp (Ctenopharyngodon idella)
December 2025
Choline is an essential nutrient for fish, and its metabolites are components of all membrane systems. Membrane phospholipids play an important role in maintaining the morphology and function of mitochondria,...
New functions of enzymatic cottonseed protein: Improvement of intestinal digestion and absorption, structure and microbial composition of juvenile yellow catfish (Pelteobagrus fulvidraco)
December 2025
Enzymatic cottonseed protein (ECP) is a functional peptide product reported to have antioxidant and immunomodulatory properties. This study focused on how the intestinal apical junction complex (AJC)...
Effects of defatted black soldier fly larvae meal on growth, nutrient digestibility, hepatopancreas biochemistry, intestinal microbiota, and phosphorus discharge of giant freshwater prawn (Macrobrachium rosenbergii)
December 2025
In recent years, the use of insect meal in feed has been regarded as an important alternative to fishmeal. Defatted black soldier fly larvae meal (BSFLM), derived from Hermetia illucens, is a promising...
Supplementation with Xinjiang licorice extract in diets enhanced the growth performance and intestinal immunity of broilers
December 2025
Xinjiang is rich in high quality licorice resources. However, as a relatively new production area, the licorice resources have not been fully utilized, resulting in a certain degree of waste. To enhance...
Supplementation of β-mannanase alone or in combination with xylanase and β-glucanase enhanced growth performance, non-starch polysaccharide degradation, and gastrointestinal environment of broilers offered wheat-based diets
December 2025
Nutritional strategies to enhance the utilization of undigested dietary components for sustainability and better production efficiency are constantly being explored in poultry. This study aimed to investigate...
Effects of inulin on growth performance and intestinal health of broilers by modulating intestinal microbiota and metabolome
December 2025
Inulin, a natural dietary fiber, confers multiple physiological benefits. However, the effects of inulin on the liver and intestinal health of broilers remain unclear. The study investigated the effects...
Spatiotemporal dynamics of mucosa-associated Lactobacillus along the small intestine and its response to 2′-fucosyllactose and galacto-oligosaccharides in piglets
December 2025
Early-life colonization of Lactobacillus in the gut is crucial for immediate and lifelong health. The intestinal mucosa is a key interface of host–microbiota interaction, but the colonization patterns...
Dose-dependent inhibitory effects of an investigational feed additive containing bromoform on methane emissions from cattle fed fresh pasture
December 2025
Bromoform, a bioactive compound in certain seaweeds, has gained attention for its methane-mitigating effects in ruminants. Research is underway to use synthetic bromoform as an alternative for providing...
Influence of coated cobalamin on lactation performance, nutrient digestion, and proteins related to mammary epithelial cell proliferation and milk fatty acid synthesis in dairy cows
December 2025
Cobalamin (vitamin B12, VB12) has the potential to enhance the digestion of dietary nutrients, optimize energy distribution, and stimulate the proliferation of mammary epithelial cells (MECs), which...
Effects of proline on growth performance, protein synthesis and cold resistance in white shrimp (Litopenaeus vannamei)
December 2025
This study aimed to explore the effects of proline on growth, protein synthesis, and cold resistance of Pacific white shrimp (Litopenaeus vannamei). A total of 720 juvenile shrimp (0.37 ± 0.00 g) were...
Effects of the α-ketoglutaric acid on the performance, hair follicle development and antioxidant capacity of Rex rabbits
December 2025
The aim of this study was to investigate the effects of α-ketoglutaric acid (AKG) supplementation on hair follicle development and to evaluate the effects on performance and antioxidant capacity in...
Low-phosphorus diet: Maintenance of growth performance and mitigation of fecal phosphorus excretion in Xia-Nan cattle
December 2025
This study was to evaluate how low phosphorus (P) diets affect growth performance and fecal P excretion in Xia-Nan cattle and to elucidate the underlying mechanisms. Thirty-two healthy Xia-Nan bulls...
Metabolomic signatures reveal mechanisms of rumen-protected glutathione in mitigating oxidative stress and regulating inflammatory networks in transition dairy cows
December 2025
Glutathione (GSH) is widely found in animal cells and is essential for combating oxidative stress and inflammation. However, whether dietary GSH alleviates these processes in dairy cows remains unknown....
Multi-omics analysis revealed coordinated responses of rumen microbiota and epithelium of goats to dietary supplementation of glucosamine selenium
December 2025
Selenium (Se) is one of the essential trace elements for ruminants. The impact of varying dietary Se levels on rumen epithelium and microbiota remains inadequately studied. This study used multi-omics...
The versatility of Bacillus tequilensis Bt-CO as an additive: Antagonizing pathogens, enhancing immunity, promoting intestinal health, and optimizing gut microbiota of tilapia
December 2025
Probiotics are gaining increasing attention as potential alternatives to antibiotics for enhancing the health and welfare of aquatic organisms. However, identifying and developing highly effective probiotic...
Potassium carbonate improves milk quality by enhancing rumen metabolism in Holstein cows
Available online 31 December 2025
Mid-lactation is a key stage in dairy production characterized by high milk yields and metabolic stress in cows. Dietary potassium carbonate may enhance milk quality, but its response mechanisms, particularly...
4-Methylesculetin improves the growth performance of grass carp (Ctenopharyngodon idella) by enhancing the proliferation and structural integrity of the intestinal epithelium
Available online 31 December 2025
Animal intestines are extremely susceptible to the adverse effects of feed and external conditions within intensive production systems. 4-Methylesculetin (4-ME) is a natural coumarin with a catechol...
Thymol modulates rumen barrier function and inflammation in feed-restricted lambs
Available online 31 December 2025
Thymol, with antimicrobial, antioxidative, and anti-inflammatory properties, shows promise in improving epithelial barrier function and reducing inflammation. This study investigated whether thymol...