Ruminal microbiota-derived inosine alleviates metabolic disorders in dairy cows supplemented with grape seed extract
December 2025
Ruminal microbiota and their metabolites can shape host metabolic responses. Grape seed extract (GSE) can modulate ruminal microbiota profiles and metabolites in vitro, thus, underscoring their potential...
Disequilibrium feeding pattern more consistent with egg-laying physiology improves eggshell quality of laying hens during late laying period
December 2025
Disequilibrium feeding pattern, as a new feeding technique, more suitable for egg-laying physiology, was feeding two-thirds diet to hens after 14:00 every day without modifying diet nutrient levels...
Increased maternal valine intake in low-protein diets accelerates growth performance of suckling piglets by improving mammary gland–fetal intestinal metabolism
December 2025
Low-protein (LP) diets are increasingly recognized as a cost-effective and efficient strategy in the global livestock industry. Although previous studies have demonstrated that increased valine intake...
Supplementation with Lycium barbarum byproducts improves energy and nitrogen metabolism, and reduces methane emissions in sheep grazing alfalfa/tall fescue pastures
December 2025
Functional native herbage (FNH), rich in bioactive components and secondary metabolites, holds potential for enhancing the productivity of grazing livestock and mitigating methane (CH4) emissions. The...
Impacts of Andrographis paniculata supplementation on health and productivity in monogastric farm animals: A comprehensive review
December 2025
Growing concerns about antibiotic resistance and the pursuit for natural alternatives in animal production have driven the search for dietary additives that promote health and sustainability, without...
Evaluating soybean protein concentrate hydrolysate as a fishmeal substitute in the diet for mandarin fish (Siniperca chuatsi): Based on growth, intestinal health, flesh quality and nutrient metabolism
December 2025
The present experiment investigated the effects of soybean protein concentrated hydrolysate (SPCH) replacing fishmeal (FM) on the growth performance, intestinal health, flesh quality, and nutrient metabolism...
Multi-omics analysis reveals the mechanism of rosemary extract supplementation in increasing milk production in Sanhe dairy cows via the “rumen-serum-milk” metabolic pathway
December 2025
Rosemary extract (RE) has shown potential as a plant-derived feed additive, but its effects on Sanhe dairy cows are still unknown. In this study, 30 multiparous Sanhe dairy cows (days in milk 171 ±...
Folic acid improves intestinal function in grass carp (Ctenopharyngodon idella): Revealing a new perspective of DNA methyltransferases and PP2A-p38 signaling pathway in intestinal epithelial function
December 2025
The beneficial effects of folic acid (FA) on intestinal barrier function are well recognized, however the underlying molecular mechanisms remain largely unexplored. This study aimed to investigate the...
Effects of dietary valine/isoleucine ratio and slaughter weight on the composition of pork flavor precursors
December 2025
This study aimed to investigate the effects of dietary valine/isoleucine (V/I) ratio and slaughter weight on the profile of pork flavor precursors. Metabolomics and volatilomic profiling were performed...
Purslane supplementation improved antioxidant capacity and milk quality potentially through rumen microbiota in dairy goats
December 2025
Purslane is a common plant with medicinal and edible homology that displays potential as a dietary supplement. In this study, this experiment aimed to investigate the effects of purslane on the health...
Epigallocatechin-3-gallate supplementation regulates glucose redistribution through its potential endogenous receptor in grass carp (Ctenopharyngodon idella)
December 2025
Exploring exogenous additives to enhance non-protein energy ingredient utilization in fish is highly anticipated. Epigallocatechin-3-gallate (EGCG) is a prominent polyphenol found in green tea. To assess...
Multi-omics reveal beneficial effects of chrysanthemum stalks on growth performance and immune function in Hu sheep
December 2025
Chrysanthemum stalks (CS), a plant by-product, often face underutilization and resource wastage. This study aimed to explore the effects of partially replacing peanut vines (PV) in the diet with CS...
Transcriptomic analysis reveals the immunomodulatory role of Clostridium autoethanogenum protein on Litopenaeus vannamei under variable salinity conditions
December 2025
Salinity is a critical environmental factor in aquaculture, and Clostridium autoethanogenum protein (CAP) shows potential as a new feed protein source. This 8-week study compared two diets (fish meal...
Lactobacillus strains from sows improve swine appetite by reducing the pro-inflammatory cytokine concentrations
December 2025
Lactational feed intake (LFI) is important for the efficiency of sow production. Previous studies indicated that the gut microbiota participated in host appetite regulation. The role of the gut microbiota,...
New insights into methionine’s role in maintaining intestinal stem cell regeneration via autophagy regulation
December 2025
As an essential amino acid, methionine (Met) is crucial for several biological functions, including protein synthesis, cell proliferation, and protection against oxidative stress. As research uncovers...
Increasing carbohydrates or nitrogenous compounds by cecal infusion leads to an opposite influence on colonic microbiota and host metabolism in a pig model
December 2025
Gut microbes, particularly those in the hindgut, play an important role in fermenting undigested nutrients (carbohydrates and proteins) and in regulating host metabolism via the gut-liver metabolic...
Replacing fishmeal with composite plant protein meal affects nutrient metabolism via mTOR signaling pathway of Pacific white shrimp (Litopenaeus vannamei)
December 2025
This study evaluated the effects of a fishmeal-reduced diet containing a composite plant protein meal (soybean meal:peanut meal:gluten meal ratio = 20:10:3) on growth performance, metabolic homeostasis,...
Effects of coarse corn or oat hulls on growth performance, intestinal health, and microbiota modulation in underperforming broilers
December 2025
Intra-flock body weight (BW) variability in broilers increases production costs, as underperforming chicks often show suboptimal gut development and performance. Increasing grain particle size and dietary...
Terpine-4-ol alleviates lipopolysaccharide-induced intestinal injury in weaned piglets by regulating intestinal epithelial cell homeostasis via the Wnt/β-catenin signaling pathway
December 2025
This study aims to elucidate intestinal injury from the perspective of intestinal epithelial cell homeostasis and to explore the modulatory roles of terpine-4-ol (a major bioactive component of tea...
Novel insights into choline's role in promoting myofiber hypertrophy and mitochondrial function in muscle of sub-adult grass carp (Ctenopharyngodon idella)
December 2025
Choline is an essential nutrient for fish, and its metabolites are components of all membrane systems. Membrane phospholipids play an important role in maintaining the morphology and function of mitochondria,...
New functions of enzymatic cottonseed protein: Improvement of intestinal digestion and absorption, structure and microbial composition of juvenile yellow catfish (Pelteobagrus fulvidraco)
December 2025
Enzymatic cottonseed protein (ECP) is a functional peptide product reported to have antioxidant and immunomodulatory properties. This study focused on how the intestinal apical junction complex (AJC)...
Effects of defatted black soldier fly larvae meal on growth, nutrient digestibility, hepatopancreas biochemistry, intestinal microbiota, and phosphorus discharge of giant freshwater prawn (Macrobrachium rosenbergii)
December 2025
In recent years, the use of insect meal in feed has been regarded as an important alternative to fishmeal. Defatted black soldier fly larvae meal (BSFLM), derived from Hermetia illucens, is a promising...
Supplementation with Xinjiang licorice extract in diets enhanced the growth performance and intestinal immunity of broilers
December 2025
Xinjiang is rich in high quality licorice resources. However, as a relatively new production area, the licorice resources have not been fully utilized, resulting in a certain degree of waste. To enhance...
Supplementation of β-mannanase alone or in combination with xylanase and β-glucanase enhanced growth performance, non-starch polysaccharide degradation, and gastrointestinal environment of broilers offered wheat-based diets
December 2025
Nutritional strategies to enhance the utilization of undigested dietary components for sustainability and better production efficiency are constantly being explored in poultry. This study aimed to investigate...
Effects of inulin on growth performance and intestinal health of broilers by modulating intestinal microbiota and metabolome
December 2025
Inulin, a natural dietary fiber, confers multiple physiological benefits. However, the effects of inulin on the liver and intestinal health of broilers remain unclear. The study investigated the effects...