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Open access

ISSN: 2666-3376
CN: 51-1812/R
p-ISSN: 2097-6291

Exercise snacks and physical fitness in sedentary populations

Physical inactivity remains a pressing global public health concern. Prolonged periods of sedentary behavior have been linked to heightened risks of non-communicable diseases such as cardiovascular...

Evolution of resistance training in women: History and mechanisms for health and performance

Throughout history, cultural norms and stereotypes have discouraged resistance training in women. Today, as awareness and acceptance of resistance training in women has grown, supported by scientific...

Creatine monohydrate supplementation for recovery from muscle disuse: Timing matters

Creatine monohydrate supplementation is best known as an ergogenic aid. However, its potential role in recovery from muscle disuse atrophy has attracted increasing scrutiny in healthy and clinical populations....

Beyond physical exhaustion: Understanding overtraining syndrome through the lens of molecular mechanisms and clinical manifestation

Overtraining Syndrome (OTS) is a condition resulting from excessive physical activity without adequate recovery, predominantly affecting elite athletes and military personnel. While overreaching can...

Physical activity, exercise, and mental health of healthy adolescents: A review of the last 5 ​years

The mental health of adolescents is a priority for successful development. Physical activity (PA) and exercise can have effects on the mental health of adolescents. This review analysed the effect that...

Exercising the brain: Molecular pathways linking exercise, neuronal mitochondria, and synaptic plasticity

Regular exercise is the most effective lifestyle intervention to improve cognitive function and reduce the risk of age-related neurodegenerative diseases. However, the underlying mechanisms are not...

Physical activity, exercise, and chronic diseases: A brief review

Chronic diseases are the leading cause of death worldwide with increasing prevalence in all age groups, genders, and ethnicities. Most chronic disease deaths occur in middle-to low-income countries...

Defecation after magnesium supplementation enhances cognitive performance in triathletes

Constipation is correlated with diminished cognitive function, revealing a possible rectum-brain connection. In this counter-balanced crossover trial, 13 elite triathletes underwent a Stroop test to...

Mechanisms of exercise against anxiety disorder: A review of the research progress

This review aims to explore the efficacy of exercise in the treatment of anxiety disorders and its underlying mechanisms, summarizing recent research advances and focusing on the potential biological...

Effects of maximal versus submaximal intended velocity resistance training on muscular fitness adaptations in older adults: A systematic review and meta-analysis

This systematic review aimed to: 1) explore muscular fitness adaptations (e.g., muscle mass, muscle strength, functional performance) in older adults (≥ 60 years) following exercise with resistance...

Warming up to improved performance? Effects of different specific warm-up protocols on neuromuscular performance in trained individuals

This study investigated the effects of varying the set number and loads in specific warm-up (SWU) protocols on resistance training (RT) session performance....

Effect of classroom-based physical activity interventions on attention and on-task behavior in schoolchildren: A systematic review

Physical activity in children is associated with several cognitive benefits. Since children and adolescents spend an increasing amount of time engaged in sedentary behavior both at school and in their...

Molecular vehicles for therapeutic delivery of lactate in exercise and medicine

Once thought of as a dead-end metabolite, the product of anaerobic, oxygen-limited metabolism, we now know that lactate is produced under fully oxygenated conditions, such as after consuming dietary...

Does longer-muscle length resistance training cause greater longitudinal growth in humans? A systematic review

This paper aimed to systematically review the literature regarding the effects of resistance training (RT) performed at longer-muscle length (LML) versus shorter-muscle length (SML) on proxy measurements...

Update: Is exercise-induced oxidative stress a friend or foe?

Free radicals (radicals) are highly reactive atoms or molecules that contain one or more unpaired electrons in their outermost shell. The first evidence that muscular exercise increases radical production...

Human behavioral basis for recommending changes to the physical activity guidelines

A growing body of evidence supports the central role of human behavior and affect in the promotion of physical activity (PA), yet a persistent gap remains between PA guidelines and actual population...

Exercise-induced lysosomal adaptations in skeletal muscle

The adoption of a regular exercise program has immense benefits for whole body health, and for improving the quality of skeletal muscle. This is important as muscle is involved in metabolism, locomotion,...

Gait patterns in children with autism spectrum disorder: A systematic review

Differences in walking patterns have been observed by clinicians working with children with Autism Spectrum Disorders (ASD). Different gait parameters have been studied and emerged through the recent...

Effect of percussive massage treatment and static stretching on muscle tone, stiffness, and strength recovery after exercise-induced muscle fatigue: A randomized controlled study

The aim of this study was to compare the effects of percussive massage treatment and static stretching on muscle tone, stiffness, and strength recovery following exercise fatigue. Sixty subjects were...

Emerging mechanisms associated with disuse-induced skeletal muscle atrophy

Skeletal muscle atrophy resulting from disuse represents a significant clinical challenge, characterized by reduced myofiber and muscle tissue size, net protein loss, and functional decline. Although...

Limitations and future directions of the functional movement screen in predicting sports injuries

Accurate risk assessment is crucial in preventing sports-related injuries. Physical therapists, strength and conditioning coaches, and other practitioners utilized the Functional Movement Screen (FMS)...

The metabolic cost of steep incline treadmill walking

Uphill walking is a popular low-impact exercise for fitness and weight management, but most treadmills are limited to 12%–15% grades. Few studies have examined the metabolic cost of more extreme gr...

Impact of nutrition on long COVID

Long COVID is characterized by a group of persistent symptoms following the acute SARS-COV2 infection, which presented a multifaceted challenge to the healthcare systems all over the globe. The long...

2020 WHO guidelines on physical activity and sedentary behavior

The World Health Organization released new guidelines on physical activity and sedentary behaviour in November 2020. This commentary summarises these guidelines, including the new elements. An evaluation...

Lactate as a candidate mediator of high-intensity interval training (HIIT)-induced gut microbiome remodeling

Exercise is a critical modulator of the gut microbiome; however, its underlying mechanisms remain incompletely understood. Here, we investigated whether lactate, a key metabolite produced during exercise,...

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