Physical activity, exercise, and mental health of healthy adolescents: A review of the last 5 years
May 2025
The mental health of adolescents is a priority for successful development. Physical activity (PA) and exercise can have effects on the mental health of adolescents. This review analysed the effect that...
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Physical activity, exercise, and chronic diseases: A brief review
December 2019
Chronic diseases are the leading cause of death worldwide with increasing prevalence in all age groups, genders, and ethnicities. Most chronic disease deaths occur in middle-to low-income countries...
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Defecation after magnesium supplementation enhances cognitive performance in triathletes
March 2025
Constipation is correlated with diminished cognitive function, revealing a possible rectum-brain connection. In this counter-balanced crossover trial, 13 elite triathletes underwent a Stroop test to...
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Exercise snacks and physical fitness in sedentary populations
January 2025
Physical inactivity remains a pressing global public health concern. Prolonged periods of sedentary behavior have been linked to heightened risks of non-communicable diseases such as cardiovascular...
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Evolution of resistance training in women: History and mechanisms for health and performance
Available online 3 February 2025
Throughout history, cultural norms and stereotypes have discouraged resistance training in women. Today, as awareness and acceptance of resistance training in women has grown, supported by scientific...
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Myocarditis – A silent killer in athletes: Comparative analysis on the evidence before and after COVID-19 pandemic
September 2024
Myocarditis is a rare cardiomyocyte inflammatory process, typically caused by viruses, with potentially devastating cardiac sequalae in both competitive athletes and in the general population. Investigation...
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Does longer-muscle length resistance training cause greater longitudinal growth in humans? A systematic review
Available online 6 March 2025
This paper aimed to systematically review the literature regarding the effects of resistance training (RT) performed at longer-muscle length (LML) versus shorter-muscle length (SML) on proxy measurements...
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Clinical gait analysis in older children with autism spectrum disorder
June 2024
Individuals with autism spectrum disorder (ASD) often exhibit motor deficits that increase their risk of falls. There is a lack of understanding regarding gait biomechanics demonstrated by older children...
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Current knowledge about pyruvate supplementation: A brief review
December 2024
Pyruvate is a three-carbon ketoacid that occurs naturally in cells. It is produced through enzymatic reactions in the glycolytic pathway and plays a crucial role in energy metabolism. Despite promising...
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Health benefits of physical activity: What role does skeletal muscle-organ crosstalk play?
Available online 28 February 2025
The observation that physical activity (PA) reduces the risk of coronary heart disease dates back more than 70 years ago and it is now established that regular PA reduces all-cause mortality, in part,...
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Exercise is mitochondrial medicine for muscle
December 2019
Mitochondria are vital organelles that provide energy for muscle function. When these organelles become dysfunctional, they produce less energy as well as excessive levels of reactive oxygen species...
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Post-workout supplementation with CoQ10 and sports drink on exercise performance and muscle recovery after exercise in normal and overweight males
Available online 27 February 2025
Post-workout supplementation has been used in athletes and recreational exercisers; however, responses between normal and overweight individuals on exercise performance and muscle recovery are less...
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Inflammation, physical activity, and chronic disease: An evolutionary perspective
March 2020
Low-grade inflammation is emerging as a common feature of contemporary metabolic, psychiatric, and neurodegenerative diseases. Both physical inactivity and abdominal adiposity are associated with persistent...
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Going nuclear: Molecular adaptations to exercise mediated by myonuclei
March 2023
Muscle fibers are multinucleated, and muscle fiber nuclei (myonuclei) are believed to be post-mitotic and are typically situated near the periphery of the myofiber. Due to the unique organization of...
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High intensity interval training and molecular adaptive response of skeletal muscle
December 2019
Increased cardiovascular fitness, V˙O2max, is associated with enhanced endurance capacity and a decreased rate of mortality. High intensity interval training (HIIT) is one of the best methods to increase...
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Post-operative protein supplementation following orthopaedic surgery: A systematic review
March 2024
Decreased mechanical loading after orthopaedic surgery predisposes patients to develop muscle atrophy. The purpose of this review was to assess whether the evidence supports oral protein supplementation...
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Mechanisms of muscle repair after peripheral nerve injury by electrical stimulation combined with blood flow restriction training
May 2025
This review elucidates the impact of electrical stimulation (ES) and blood flow restriction (BFR) training on muscle function. ES induces a transformation in muscle fibers type by rearranging myosin...
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Combined extracorporeal shockwave therapy and exercise for the treatment of tendinopathy: A narrative review
March 2022
Tendinopathy is a chronic degenerative musculoskeletal disorder that is common in both athletes and the general population. Exercise and extracorporeal shockwave therapy (ESWT) is among the most common...
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Reasons and promotion strategies of physical activity constraints in obese/overweight children and adolescents
March 2024
To explore the reasons for low levels of physical activity in obese/overweight children and adolescents and to propose appropriate strategies to promote their physical activity (PA). This review followed...
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Effects of high-intensity intermittent cross-training on maximal oxygen uptake
May 2025
We investigated the effects of high-intensity intermittent cross-training (HIICT) on maximal oxygen uptake (V˙O2max). The HIICT consisted of alternating intermittent 20-s treadmill running (1st, 3rd,...
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Beyond physical exhaustion: Understanding overtraining syndrome through the lens of molecular mechanisms and clinical manifestation
July 2025
Overtraining Syndrome (OTS) is a condition resulting from excessive physical activity without adequate recovery, predominantly affecting elite athletes and military personnel. While overreaching can...
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2020 WHO guidelines on physical activity and sedentary behavior
June 2021
The World Health Organization released new guidelines on physical activity and sedentary behaviour in November 2020. This commentary summarises these guidelines, including the new elements. An evaluation...
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Exercise and nutrition benefit skeletal muscle: From influence factor and intervention strategy to molecular mechanism
December 2024
Sarcopenia is a progressive systemic skeletal muscle disease induced by various physiological and pathological factors, including aging, malnutrition, denervation, and cardiovascular diseases, manifesting...
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Implications of the COVID-19 pandemic on athletes, sports events, and mass gathering events: Review and recommendations
September 2023
Since the coronavirus disease 19 (COVID-19), which caused several respiratory diseases, was formally declared a global pandemic by the World Health Organization (WHO) on March 11, 2020, it affected...
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Prevalence of Achilles tendinopathy in physical exercise: A systematic review and meta-analysis
September 2022
This comprehensive systematic review and meta-analysis assessed the prevalence of Achilles tendinopathy (AT) in physical exercise (PE). Specifically, we estimate the overall risk of AT in physical exercise...
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