The new frontier of drug delivery through nanotechnology
December 2023
Nanomedicine is a promising platform for drug delivery systems, offering enhanced therapeutic outcomes and reduced side effects. Nanomicelles are a class of nanoparticles that have shown great potential...
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Recent trends in electronic skin for transdermal drug delivery
December 2023
This paper presents an in-depth discussion of the development of electronic skin (e-skin) devices for transdermal drug delivery (TDD) for skin health management. E-skin devices, grounded in flexible...
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“In-silico exploration of cyanobacterial bioactive compounds for managing diabetes: Targeting alpha-amylase and beta-glucosidase"
December 2023
This research investigates the potential of bioactive compounds derived from cyanobacteria as inhibitors of alpha-amylase and beta-glucosidase enzymes, which are involved in starch digestion and glucose...
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Enhancing drug related problem (DRP) management in Indian healthcare through AI integration: An insight view
December 2023
The integration of Artificial Intelligence (AI) technologies in Indian healthcare is set to revolutionize drug related problem (DRP) management, ensuring patient safety and optimizing healthcare outcomes....
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Cardioprotective potential of Lavandula stoechas against isoprenaline-induced myocardial necrosis in rats
December 2023
This study assessed Lavandula stoechas flower extract's impact on Isoprenaline-induced myocardial necrosis in rats. Five groups of five rats each were used. Group I received 1 ml/kg normal saline orally...
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HPLC fingerprints of polygonum cuspidatum power and polygonum cuspidatum ointment and simultaneous determination of six constituents
December 2023
Polygonum Cuspidate (P. cuspidatum) is a traditional topical preparation of Chinese medicine. The aim of this study was to develop HPLC fingerprints for P. cuspidatum Powder and P. cuspidatum Ointment,...
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Nanoformulation mediated transdermal delivery of anti-diabetic drugs: an updated review
December 2023
Diabetes mellitus is a concern of disorder globally and which is increasing continuously. Diabetic complications lead to physical, mental and societal issues to patients. Oral medications are being...
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AI-driven smart pharmacology
December 2023
With the progress of digital technology and innovative drug R&D, machine learning and data-driven algorithms have been increasingly used to support the core work of pharmaceutical areas such as new...
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Predicting vancomycin trough serum concentration in augmented renal clearance patients through an artificial neural network model
December 2023
Artificial neural network (ANN) model has been developed in prediction of serum drug concentration. The aim of this study was verifying the accuracy of ANN model in predicting vancomycin trough serum...
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Omicron variant raises global concerns: Increased hospitalization and India's vaccination advantage
December 2023
The newly identified COVID-19 variant, B.1.1.529, initially detected in South Africa, was officially designated as the “Omicron” variant by the World Health Organization on November 26, 2021. This variant...
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Role of epigenetics in cardiovascular diseases: An out and out check
December 2023
Epigenetics is a rapidly growing field that deals with the study of heritable changes in gene expression that occur without a change in DNA sequence. DNA methylation, histone modification, and noncoding...
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Intelligent Pharmacy's applications of cyclosporine
December 2023
Cyclosporine (CsA) is a classical immunosuppressant that requires therapeutic drug monitoring to determine efficacy and adverse effects due to the individualized nature of its drug metabolism. Emerging...
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Transferosomal gel for transdermal delivery of insulin: Formulation development and ex vivo permeation study
December 2023
The study was to develop a transdermal formulation of insulin, determine its pharmaceutical characteristics, and finally test its efficacy. In the current study - Transfersomes were selected as the...
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Current status and cost burden of non-first-line treatment in ITP: A multicenter study based on real-world data in China
December 2023
Eltrombopag, the first TPO-RA approved for the treatment of ITP, resulted in rapid and sustained increases in platelet counts, significant reductions in bleeding events and concomitant medications,...
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Azithromycin and co-trimoxazole-induced oral thrush: A case report from the perspective of pharmacy
December 2023
Oral thrush, also known as candidiasis, is one of the most common parasitic infections of the human mouth. A 35-year-old female patient complaining of breathlessness, cough, and fever. She was prescribed...
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Prostate cancer prediction model: A retrospective analysis based on machine learning using the MIMIC-IV database
December 2023
Prostate cancer is a common malignant tumor in men and early diagnosis and treatment are crucial for the survival rate of patients. This study aimed to establish a machine learning-based prostate cancer...
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Antiplatelet and thrombolytic activity of phenolic-insistent fractions from the new-fangled stem of Ficus benghalensis with concurrent GC-MS analysis
December 2023
Ficus benghalensis is the ingredient of a variety of Ayurvedic herbal formulations for the management of blood-related illnesses. In the current study, the new-fangled stem ethanol extract fractions...
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Guillain–barré syndrome (GBS) with compressive myelopathy: A case report
December 2023
Guillain-Barre syndrome is an autoimmune disorder with the most common clinical presentation of neuromuscular paralysis. Here we have reported a rare case of GBS in a 60-year-old male patient admitted...
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Scope of health care system in rural areas under Medical 4.0 environment
December 2023
Health is crucial for personal happiness, productivity, and fulfillment. It impacts physical well-being, mental health, longevity, academic and professional success, and interpersonal relationships....
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A green alternative: Evaluation of Solanum torvum (Sw.) leaf extract for control of Aedes aegypti (L.) and its molecular docking potential
Available online 30 November 2023
Due to the unavailability of effective vaccines and treatments, mosquito-borne diseases continue to pose a threat to global public health. Insecticide-treated mosquito nets and room sprays have both...
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Towards designing of some potential new autoimmune disorder inhibitors using crystal structures and Hirshfeld surface analyses in combination with molecular docking and molecular dynamics simulations
Available online 29 November 2023
The emergence of multi-drug-resistant autoimmune diseases poses a significant risk to human health and has garnered global attention. In this study, metformin and sulfasalazine have been used as starting...
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Comparative evaluation of carvedilol and pitavastatin for antihyperlipidemic activity in tyloxapol-induced hyperlipidemia in Wistar rats
Available online 28 November 2023
Aim of the study was designed to investigate the antihyperlipidemic activity of carvedilol and pitavastatin in tyloxapol-induced hyperlipidemia in Wistar rats. The rats were randomly divided into 6...
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Pharmacological, phytochemical Chemistry and therapeutic qualities of Mimusops elengi
Available online 24 November 2023
Mimusops elengi, a widely distributed tree species in tropical regions, has been used for centuries in traditional medicine due to its numerous therapeutic properties. In this study, we conducted a...
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Modelling of novel bornoel analogs as Influenza A Virus inhibitors through genetic function approximation, comparative molecular fields, molecular docking, and ADMET/Pharmacokinetic studies
Available online 22 November 2023
Influenza A Virus (IAV) is a human respiratory pathogen prone to mutations and genome re-assortment leading to global pandemics. In this study, we applied the molecular modelling strategies such as,...
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A review of Vernonia cinerea L. ethno-medicinal uses and pharmacology shows that it could be a useful plant for medical purposes
Available online 17 November 2023
Vernonia cinereaL., also known as purple fleabane, is a plant with medicinal properties that have been traditionally used to treat respiratory infections, digestive disorders, and skin conditions. Its...
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