Total parenteral nutrition: A boon to non-functional gastrointestinal patients
April 2024
About 25 years ago it became apparent that TPN had value in the management of critically ill patients who were not being normally nourished because they either had gastrointestinal failure or could...
Share article
Risk factors for clinical treatment failure and death in patients with ceftazidime-avibactam-resistant Gram-negative bacteria: A single-centre retrospective analysis
April 2024
In recent years, the number of Gram-negative bacteria (GNB) resistant to ceftazidime-avibactam (CZA) isolated from clinic has been increasing. We aimed to evaluate the clinical efficacy in patients...
Share article
Ziziphus mauritiana: An in-depth review of its medicinal attributes and pharmacological activities
April 2024
The plant species Ziziphus mauritiana, recognized by its common name Indian jujube, is classified within the Rhamnaceae family. It has been widely used in traditional medicine for its therapeutic properties,...
Share article
Towards designing of some potential new autoimmune disorder inhibitors using crystal structures and Hirshfeld surface analyses in combination with molecular docking and molecular dynamics simulations
April 2024
The emergence of multi-drug-resistant autoimmune diseases poses a significant risk to human health and has garnered global attention. In this study, metformin and sulfasalazine have been used as starting...
Share article
Simplifying the concept of level of evidence in lay language for all aspects of learners: In brief review
April 2024
The level of evidence is a fundamental structure for assessing the excellence of evidence while making healthcare choices. It assesses medical research according to its structure, credibility, and relevance....
Share article
A green alternative: Evaluation of Solanum torvum (Sw.) leaf extract for control of Aedes aegypti (L.) and its molecular docking potential
April 2024
Due to the unavailability of effective vaccines and treatments, mosquito-borne diseases continue to pose a threat to global public health. Insecticide-treated mosquito nets and room sprays have both...
Share article
Unlocking the phytochemicals in unopened pitcher fluids of Nepenthes khasiana -a GC–MS study
April 2024
The pitcher plant, Nepenthes khasiana is utilized by several indigenous groups in Meghalaya, India owing to its medicinal properties. Due to their therapeutic qualities, a pioneer work was undertaken...
Share article
A novel anoikis-related gene signature predicts in lung adenocarcinoma
April 2024
To generate a prognostic model prognosis based on anoikis-related genes (ANRGs) expression for Lung adenocarcinoma (LUAD), an exploration of the prognostic value of ANRGs in LUAD was conducted....
Share article
Comparative evaluation of carvedilol and pitavastatin for antihyperlipidemic activity in tyloxapol-induced hyperlipidemia in Wistar rats
April 2024
Aim of the study was designed to investigate the antihyperlipidemic activity of carvedilol and pitavastatin in tyloxapol-induced hyperlipidemia in Wistar rats. The rats were randomly divided into 6...
Share article
Molecular docking studies of some benzoxazole and benzothiazole derivatives as VEGFR-2 target inhibitors: In silico design, MD simulation, pharmacokinetics and DFT studies
April 2024
Breast cancer, a deadly disease among women, demands effective interventions due to its global impact, with over one million annual cases. Current anti-breast cancer drugs displays several side effects,...
Share article
Docking study of novel designed indazole derivatives against topoisomerase-II DNA gyrase enzyme for antibacterial screening
April 2024
Aim of the study was designed for the design of novel indazole derivatives and evaluation of their docking against topoisomerase-II DNA gyrase enzyme for the antibacterial screening. Different novel...
Share article
Modelling of novel bornoel analogs as Influenza A Virus inhibitors through genetic function approximation, comparative molecular fields, molecular docking, and ADMET/Pharmacokinetic studies
April 2024
Influenza A Virus (IAV) is a human respiratory pathogen prone to mutations and genome re-assortment leading to global pandemics. In this study, we applied the molecular modelling strategies such as,...
Share article
Nanoliposome: as a smart nanocarrier in transdermal drug delivery system
Available online 25 April 2024
In the current advancement of drug delivery systems, nanoliposome vesicles act as a modernized technology for the encapsulation of bioactive agents. The prerequisite to expand biocompatible, structured,...
Share article
Nanoliposome enabled topical gel-based drug delivery system of ivermectin: Fabrication, characterization, in vivo and in vitro investigation
Available online 21 April 2024
Nanoliposomes loaded with ivermectin possess the ability to deliver the drug to an intended area, ensuring optimal stability and eventual release at that precise location. The nanoliposome's size range...
Share article
Schematized Study for Tackling COVID-19 with Machine Learning (ML), Artificial Intelligence (AI), and Internet of Things (IoT).
Available online 16 April 2024
The novel Coronavirus (COVID-19) is caused by the newly identified strain of the coronavirus family severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), whose target organ is the lungs. It...
Share article
A comprehensive review on nanocarriers as a targeted delivery system for the treatment of breast cancer
Available online 5 April 2024
Breast cancer is the most common malignant tumour in women worldwide, as well as the leading cause of death from malignant tumours. All across the world, the incidence of breast cancer is steadily rising....
Share article
Suspected undeclared use of generative artificial intelligence
Available online 3 April 2024
In a recent article in Intelligent Pharmacy, a portion of the text appears to have been generated by a generative artificial intelligence (AI) system. The usage of AI is not documented in the article....
Share article
Exploring the competence of ChatGPT for customer and patient service management
Available online 22 March 2024
The modern language generation model ChatGPT, created by Open Artificial Intelligence (AI), is recognised for its capacity to comprehend context and produce pertinent content. This model is built on...
Share article
Computational transformation in drug discovery: A comprehensive study on molecular docking and quantitative structure activity relationship (QSAR)
Available online 9 March 2024
The procedure for learning and creating a new medicine is widely seen as a drawn-out and costly endeavor. Different rational strategies are considered, depending on their requirements, as potential...
Share article
Formulation, development and evaluation of Woodfordia fruticosa and β-sitosterol mediated silver nanoparticles gel for synergistic effect
February 2024
Silver nanoparticles (AgNP) are frequently utilized metallic nanoparticles in healthcare systems. In this investigation, AgNP was produced employing β-sitosterol and Woodfordia fruticosa gel for the...
Share article
Development And Evaluation of topical liposomal preparation of Walnut oil and tamarind seed oil against ageing
February 2024
Revamp of liposomal preparation inimical ageing by using a splendid treasure of herbal drugs includes non-prescription and prescription upshot. Liposomal therapy stands at the forefront of cutting-edge...
Share article
Role of natural bioactive compounds in the management of neurodegenerative disorders
February 2024
Lately, substantial exploration and study have focused on natural products, along with their bioactive compounds. Neurodegenerative diseases (NDDs) such as Alzheimer's disease (AD), Huntington's disease...
Share article
Microneedle technology- an insight into advancements, latest scholarly and patent data
February 2024
Microneedles (MN) have been used to deliver small molecular weight drugs, nucleotides, DNA, peptides, proteins, and even viruses that have been turned off. Over the past ten years, different kinds of...
Share article
Chronomodulated drug delivery systems for the treatment of hypertension: An overview
February 2024
This review paper aims to provide an overview of chronomodulated drug delivery systems for the treatment of hypertension. Hypertension is a chronic medical condition that affects millions of people...
Share article
Unravelling the influenza virus inhibitory potential: Ligand-based docking, pharmacophore, MM-GBSA, and molecular dynamic simulation of phytochemicals and cyanobacteria metabolites
February 2024
Viral outbreaks facilitated by global travel and modernity pose significant threats to global health. Influenza viruses, particularly α-influenza and β-influenza strains, have been plaguing human populations...
Share article