A hybrid deep learning framework based on VGG19 and U-Net for accurate brain tumor segmentation in MRI images
November 2026
Accurate segmentation of brain tumors from magnetic resonance imaging (MRI) is a critical task in neuro-oncology, directly impacting diagnosis, treatment planning, and patient outcomes. This study presents...
Probing electronic structures of transition metal complexes using electron paramagnetic resonance spectroscopy
February 2023
Electron paramagnetic resonance (EPR) or electron spin resonance (ESR) has been widely employed to characterize transition metal complexes. However, because of the high degree of complexity of transition...
Rapid and quantitative 1D 13C NMR analysis of polypropylene tacticity with relaxation agent and proton polarization transfer
November 2025
Polypropylene (PP) accounts for approximately 28.0% of the global polyolefin market, valued at $243.4 billion in 2022. Known for its lightweight, chemical resistance, cost-effectiveness, high strength...
A designed fusion tag improves soluble expression of nanobody in E. coli
November 2026
Nanobodies are small, single-domain antibody fragments derived from camelid heavy-chain antibodies that offer high stability, strong binding affinity, and excellent potential for therapeutic and diagnostic...
Structural anisotropy in celery stalks by microscopic MRI and polarized light microscopy
May 2026
Structural anisotropy of celery stalks was studied using T2 anisotropy in microscopic MRI (μMRI) and supplemented by quantitative polarized light microscopy (PLM) at optical resolutions. Parenchyma,...
NMR methods for investigating functionally relevant biomolecular dynamics
November 2025
The dynamics of biomolecules span across a wide range of timescales, reflecting the complexity of free energy landscapes of biomolecules. Among these, the microsecond-to-millisecond (μs–ms) timescale...
Dynamic nuclear polarization and chemically induced hyperpolarization: Progress, mechanisms, and opportunities
August 2025
Nuclear magnetic resonance (NMR) spectroscopy is a powerful and broadly used spectroscopic technique for characterizing molecular structures and dynamics. Yet the power of NMR is restricted by its inherently...
RF power design optimization in MRI system
August 2021
Magnetic resonance image quality and patient safety have been the focus of engineering and research ever since the invention of equipment in the early 1970s. In high field (or ultrahigh field) MRI systems,...
Physics-embedded CycleGAN for robust metabolite mapping in short-readout deuterium metabolic imaging
November 2026
Deuterium metabolic imaging (DMI) enables noninvasive, spatially resolved mapping of in vivo metabolism by tracking deuterium-labeled substrates and downstream products, yet it is frequently signal-to-noise-ratio...
Progress in magnetic resonance imaging of the glymphatic system
November 2024
The glymphatic system (GS) is a newly discovered brain anatomy. Its discovery improves our understanding of brain fluid flow and waste removal paths and provides an anatomical basis for the flow of...
The perspective of artificial intelligence for NMR
February 2027
Nuclear magnetic resonance (NMR) spectroscopy is an indispensable analytical technique in chemistry, biology, and medicine, offering molecular-level structural and dynamic insights for metabolite identification...
Design of a fast broadband RF switch for multi-nuclear NMR in lithium-ion batteries
November 2026
To address the need for observing the electrolyte influenced by dissolved metal ions during the charge and discharge process of lithium-ion battery, a fast-switching broadband radio frequency (RF) switch...
Solid-state NMR of vulcanized natural rubber/butadiene rubber blends: Local organization and cross-linking heterogeneities
November 2024
Elastomer blends, among which natural rubber (NR) and butadiene rubber (BR), are involved in many components of the automotive/tire industry. A comprehensive understanding of their mechanical behavior...
Numerical design of transverse gradient coil with transformed magnetic gradient field over an effective imaging area
February 2025
Gradient coil is an essential component of a magnetic resonance imaging (MRI) scanner. To achieve high spatial resolution and imaging speed, a high-efficiency gradient coil with high slew rate is required....
Magnetic resonance imaging techniques for lithium-ion batteries: Principles and applications
May 2024
Operando monitoring of internal and local electrochemical processes within lithium-ion batteries (LIBs) is crucial, necessitating a range of non-invasive, real-time imaging characterization techniques...
Rheo-NMR: A versatile hyphenated technique for capturing molecular dynamics and structure under flow
February 2024
The general development of Rheo-NMR during the last four decades as well as selective hyphenated apparatuses is presented. Based on different magnet types, the current review is divided into two categories,...
Chemical exchange saturation transfer NMR: An analytical tool and its applications
August 2026
NMR spectroscopy has proven to be a powerful tool for elucidating structural information and studying dynamic processes. Among NMR techniques, chemical exchange saturation transfer (CEST) is particularly...
Overview and progress of X-nuclei magnetic resonance imaging in biomedical studies
November 2023
Proton nuclear (1H) is the observed nucleus on which most magnetic resonance imaging (MRI) applications depend. Most traditional 1H MRI can provide structural and functional information about organisms,...
Progress in in-situ electrochemical nuclear magnetic resonance for battery research
May 2024
A thorough understanding of the fundamental electrochemical and chemical processes in batteries is crucial to advancing energy density and power density. However, the characterizations of such processes...
Deciphering the hydrogen shuttle-mediated kinetic memory of Ge-related defects in UV-grade fused quartz via in situ EPR with 3D imaging
February 2027
This study elucidates the photo-induced defect dynamics in standard UV-grade fused quartz (JGS2) by synergizing in situ electron paramagnetic resonance (EPR) spectroscopy with 3D volumetric imaging....
Operando NMR methods for studying electrocatalysis
May 2024
The combination of electrochemical measurements with spectroscopic characterizations provides valuable insights into reaction mechanisms. Nuclear magnetic resonance (NMR) spectroscopy, as a powerful...
Production of isotope-labeled nanobody KN035 in Pichia pastoris yields native-like conformation and PD-L1 binding activity comparable to KN035 expressed in mammalian cells
August 2026
Stable isotope-labeled proteins are indispensable for NMR-based structural studies. E. coli is a cost-effective and high-yield expression host, but it often fails to support proper folding and post-translational...
Using NMR-detected hydrogen-deuterium exchange to quantify protein stability in cosolutes, under crowded conditions in vitro and in cells
November 2023
We review the use of nuclear magnetic resonance (NMR) spectroscopy to assess the exchange of amide protons for deuterons (HDX) in efforts to understand how high concentration of cosolutes, especially...
NMR insights into the role of urea in cellulose dissolution: A stoichiometric study of cellobiose in NaOH/urea aqueous solution
August 2026
The mechanism underlying the enhanced dissolution of cellulose in NaOH/urea aqueous solutions has long been a subject of debate. In this study, high-resolution solution-state 1H and 13C DEPTq NMR spectroscopy...
Femtotesla atomic magnetometer for zero- and ultralow-field nuclear magnetic resonance
August 2025
Zero- and ultralow-field nuclear magnetic resonance (ZULF NMR) has experienced rapid development and provides an excellent tool for diverse research fields ranging from materials science and quantum...
