Magnetic Resonance Letters is sponsored by Innovation Academy of Precision Measurement Science and Technology, Chinese Academy of Sciences (hereinafter referred to as APM). In the early days of the Wuhan Institute of Physics and Mathematics, CAS (WIPM, CAS), one of the predecessors of APM, renowned physicist Mr. Wang Tianjuan, returned to China and...
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Volume 2 Issue 4 The parallel tetrameric DNA G-quadruplex formed by the two-repeat C9orf72 GGGGCC sequence in solution
The G-rich hexanucleotide repeat, GGGGCC (G4C2), in C9orf72 gene can fold into two kinds of eight-layer parallel tetrameric G-quadruplexes which exchange fast in solution. The formation of high-order G-quadruplexes via 5'-5'/3'-3' π-π stacking cause the death of neuron, eventually resulting in ALS/FTD.
Solution NMR as a tool in probing GPCR conformational dynamics.
Fragment-Based Drug Discovery: Stronger – Together.
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