Cyanidin-3-glucoside protects the photooxidative damage of retinal pigment epithelium cells by regulating sphingolipid signaling and inhibiting MAPK pathway
March 2024
Cyanidin-3-glucoside (C3G) is the most common anthocyanin in dark grains and berries and is a food functional factor to improve visual health. However, the mechanisms of C3G on blue light-induced retinal...
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Sugarcane leaves-derived polyphenols alleviate metabolic syndrome and modulate gut microbiota of ob/ob mice
March 2024
Sugarcane leaves-derived polyphenols (SLP) have been demonstrated to have diverse health-promoting benefits, but the mechanism of action has not been fully elucidated. This study aimed to investigate...
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Cyanidin-3-O-glucoside alleviates trimethyltin chloride-induced neurodegeneration by maintaining glutamate homeostasis through modulation of the gut microbiota
March 2024
Trimethyltin chloride (TMT) is a potent neurotoxin to cause neurodegeneration, especially in hippocampus. This study aimed to identify dietary components that can effectively attenuate TMT-induced neurodegeneration...
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Lactobacillus plantarum AR113 attenuates liver injury in D-galactose-induced aging mice via the inhibition of oxidative stress and endoplasmic reticulum stress
March 2024
Probiotics could effectively eliminate excess reactive oxygen species (ROS) generated during aging or lipid metabolism disorders, but their mechanism is unclear. The major purpose of this study was...
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Sodium butyrate alleviates fructose-induced non-alcoholic fatty liver disease by remodeling gut microbiota to promote γ-amino butyric acid production
March 2024
Sodium butyrate (NaB) can regulate lipid metabolism and inhibit hepatic steatosis. This study aimed to investigate whether NaB can alleviate fructose-induced hepatic steatosis via remodeling the gut...
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One stone two birds: electrochemical and colorimetric dual-mode biosensor based on copper peroxide/covalent organic framework nanocomposite for ultrasensentive norovirus detection
March 2024
Norovirus (NoV) is regarded as one of the most common causes of foodborne diarrhea in the world. It is urgent to identify the pathogenic microorganism of the diarrhea in short time. In this work, we...
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Plant-based meat analogues aggravated lipid accumulation by regulating lipid metabolism homeostasis in mice
March 2024
To determine the effects of plant-based meat analogues on the metabolic health and the possible mechanisms, mice were fed with a real pork diet (AP), a real beef diet (AB), a plant-based pork analogue...
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Antibacterial mechanism of kojic acid and tea polyphenols against Escherichia coli O157:H7 through transcriptomic analysis
March 2024
Escherichia coli O157:H7 is one of the major foodborne pathogenic bacterial that cause infectious diseases in humans. The previous found that a combination of kojic acid and tea polyphenols exhibited...
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The modulatory effect of oolong tea polyphenols on intestinal flora and hypothalamus gene expression in a circadian rhythm disturbance mouse model
March 2024
The interaction between host circadian rhythm and gut microbes through the gut-brain axis provides new clues for tea polyphenols to improve host health. Our present research showed that oolong tea polyphenols...
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The role of a novel antibacterial substance, cyclic opine-producing Lacticaseibacillus rhamnosus LS8 in ameliorating ulcerative colitis: a fecal microbiota transplantation study
March 2024
Intestinal microbiota imbalance may worsen the progression of ulcerative colitis (UC). Lacticaseibacillus rhamnosus LS8 (LR) has the potential ability to regulate microbiota through producing a novel...
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Influence of nitrogen status on fermentation performances of non-Saccharomyces yeasts: a review
March 2024
Nitrogen, one of the most crucial nutrients present in grapes and musts, plays a key role in yeast activities during alcoholic fermentation. Such influences are imposed on yeast growth and fermentation...
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A novel AgNPs/MOF substrate-based SERS sensor for high-sensitive on-site detection of wheat gluten
March 2024
Gluten, known as the major allergen in wheat, has gained increasing concerns in industrialized countries, resulting in an urgent need for accurate, high-sensitive, and on-site detection of wheat gluten...
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Effects of forsythin extract in Forsythia leaves on intestinal microbiota and short-chain fatty acids in rats fed a high-fat diet
March 2024
Forsythia suspensa, belonging to the deciduous shrubs of the Luteaceae family, a traditional Chinese medicine, has effects of alleviating swelling, clearing heat, detoxification and promoting blood...
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The efficiency and safety evaluation of hemoglobin hydrolysate as a non-heme iron fortifier
March 2024
Hemoglobin hydrolysate is derived from the enzymatic degradation of hemoglobin. This work aimed to evaluate whether hemoglobin hydrolysate promotes the absorption of non-heme iron and the safety of...
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Lactobacillus plantarum AR495 improves stress-induced irritable bowel syndrome in rats by targeting gut microbiota and Mast cell-PAR2-TRPV1 signaling pathway
March 2024
Probiotics have great potential in regulating intestinal pain. In this study, the effects of Lactobacillus plantarum AR495 on the visceral sensitivity and gut microbiota of irritable bowel syndrome...
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Model prediction of inactivation of Aeromonas salmonicida grown on poultry in situ by intense pulsed light
March 2024
The aim of this study was to evaluate the factors influencing the inactivation effect of intense pulsed light (IPL) on Aeromonas salmonicida grown on chicken meat and skin, and to further develop prediction...
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A core-satellite self-assembled SERS aptasensor containing a “biological-silent region” Raman tag for the accurate and ultrasensitive detection of histamine
March 2024
Herein, a novel interference-free surface-enhanced Raman spectroscopy (SERS) strategy based on magnetic nanoparticles (MNPs) and aptamer-driven assemblies was proposed for the ultrasensitive detection...
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Protective effects of oleic acid and polyphenols in extra virgin olive oil on cardiovascular diseases
March 2024
The Mediterranean diet has long been recognized as one of the most effective ways to prevent and improve cardiovascular disease. Extra virgin olive oil (EVOO) is the typical sources of fat in the Mediterranean...
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Hypoglycemic mechanism of Tegillarca granosa polysaccharides on type 2 diabetic mice by altering gut microbiota and regulating the PI3K-akt signaling pathway
March 2024
Type 2 diabetes mellitus (T2DM) is a complex metabolic disease threatening human health. We investigated the effects of Tegillarca granosa polysaccharide (TGP) and determined its potential mechanisms...
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Ganoderma lucidum: a comprehensive review of phytochemistry, efficacy, safety and clinical study
March 2024
Ganoderma lucidum, one of the most well-known edible fungi, is believed to be very beneficial for longevity and vitality. A long usage history suggests that G. lucidum has various clinical therapeutic...
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Diet and physical activity influence the composition of gut microbiota, benefit on Alzheimer’s disease
March 2024
Alzheimer's disease is a neurodegenerative disease with complex etiology. Gut microbiota influences the gut-brain axis, which may affect pathways related to the pathogenesis of Alzheimer's disease....
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Effect of sodium starch octenyl succinate-based Pickering emulsion on the physicochemical properties of hairtail myofibrillar protein gel subjected to multiple freeze-thaw cycles
March 2024
A Pickering emulsion based on sodium starch octenyl succinate (SSOS) was prepared and its effects on the physicochemical properties of hairtail myofibrillar protein gels (MPGs) subjected to multiple...
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Mechanism of action of cordycepin in the treatment of hepatocellular carcinoma via regulation of the Hippo signaling pathway
March 2024
Hepatocellular carcinoma (HCC) is one of the common most malignant tumors. This study aimed to determine the in vitro and in vivo anticancer activity of cordycepin and elucidate its mechanism of action....
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A food-grade and senescent cell-targeted fisetin delivery system based on whey protein isolate-galactooligosaccharides Maillard conjugate
March 2024
Cellular senescence is the results of aging and age-related diseases, and the development of anti-aging methods may improve health and extend longevity. The natural flavonol fisetin has been shown to...
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Blautia producta displays potential probiotic properties against dextran sulfate sodium-induced colitis in mice
March 2024
Blautia has attracted attention because of its potential efficacy in ameliorating host energy metabolism and inflammation. This study aims to investigate the influences of Blautia producta D4 on colitis...
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