Lacticaseibacillus rhamnosus Probio-M9 may be vertically transmitted from mother to infant during lactation based on faeces metagenomics
March 2024
Probiotics exert beneficial effects on the host. This study aimed to investigate whether maternally ingested Lacticaseibacillus rhamnosus Probio-M9 during pregnancy could access and colonize the infant...
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Comparative study of the effects of Tartary buckwheat seed and sprout consumption on the physiological indices and gut microbiota of C57BL/6J mice
March 2024
Tartary buckwheat (Fagopyrum tataricum) is a well-known pseudocereal for its health and economic value. However, abundant antinutritional factors (ANFs) reduces its health benefits. As reported, germination...
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Novel umami peptides from two Termitomyces mushrooms and molecular docking to the taste receptor T1R1/T1R3
March 2024
Wild edible Termitomyces mushrooms are popular in Southwest China and umami is important flavor qualities of edible mushrooms. This study aimed to understand the umami taste of Termitomyces intermedius...
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The in vitro digestion fates of diacylglycerol under different intestinal conditions: a potential lipid source for lipid indigestion patients
March 2024
The in vitro digestion models mimicking the gastrointestinal (GI) tract of general population and lipid indigestion patients (with lower levels of bile salts or pancreatic lipase) were selected to investigate...
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Aptasensing biosynthesized phosphatidylserine with a AuNPs nanozyme-based colorimetric aptasensor
March 2024
Sensitive monitoring of the target products during the biosynthesis process is crucial, and facile analytical approaches are urgently needed. Herein, phosphatidylserine (PS) was chosen as the model...
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A novel strain of Levilactobacillus brevis PDD-5 isolated from salty vegetables has beneficial effects on hyperuricemia through anti-inflammation and improvement of kidney damage
March 2024
Hyperuricemia is a metabolic disorder caused by abnormal purine metabolism, resulting in abnormally high serum uric acid. In this study, a novel Levilactobacillus brevis PDD-5 isolated from salty vegetables...
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Metabolite acetyl-L-carnitine participates in Bifidobacterium animalis F1-7 to ameliorate atherosclerotic inflammation by downregulating theTLR4/NF-κB pathway
March 2024
This study aimed to explore the effect of Bifidobacterium animalis F1-7 on the improvement of atherosclerotic inflammation. Arteriosclerosis model ApoE–/– mice were orally administered with B. animalis...
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Palmitoleic acid on top of HFD ameliorates insulin resistance independent of diacylglycerols and alters gut microbiota in C57BL/6J mice
March 2024
With the prevalence of obesity and obesity-related metabolic syndrome, such as insulin resistance in recent years, it is urgent to explore effective interventions to prevent the progression of obesity-related...
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A ratiometric fluorescent probe for hypoxanthine detection in aquatic products based on the enzyme mimics and fluorescence of cobalt-doped carbon nitride
March 2024
A ratiometric fluorescent probe for hypoxanthine (Hx) detection was established based on the mimic enzyme and fluorescence characteristics of cobalt-doped graphite-phase carbon nitride (Co doped g-C3N4)....
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Functionalized selenium nanoparticles ameliorated acetaminophen-induced hepatotoxicity through synergistically triggering PKCδ/Nrf2 signaling pathway and inhibiting CYP 2E1
March 2024
Selenium nanoparticles (SeNPs) have been demonstrated potential for use in diseases associated with oxidative stress. Functionalized SeNPs with lower toxicity and higher biocompatibility could bring...
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Lactobacillus plantarum CCFM1180 attenuates obesity induced by estrogen deficiency by activating estrogen receptor alpha in abdominal adipose tissue and regulating gut microbiota-derived metabolitesestrogen
March 2024
Lipid metabolism disorders commonly occur during menopause. Estrogen deficiency has been shown to lead to excessive energy intake and abnormal lipid metabolism in ovariectomized rats, resulting in obesity....
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Resveratrol combats chronic diseases through enhancing mitochondrial quality
March 2024
Resveratrol (RSV), as a functional food component extracted from natural plants, has been widely studied and recognized in preventing and treating various diseases, with major mechanisms including executing...
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Comparison of immune responses and intestinal flora in epicutaneously sensitized BALB/c or C57BL/6 mouse models of food allergy
March 2024
Cutaneous exposure to food allergens through a disrupted skin barrier is recognized as an important cause of food allergy, and the cutaneous sensitized mouse model has been established to investigate...
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Tb3+-nucleic acid probe-based label-free and rapid detection of mercury pollution in food
March 2024
Mercury is a threatening pollutant in food, herein, we developed a Tb3+-nucleic acid probe-based label-free assay for mix-and-read, rapid detection of mercury pollution. The assay utilized the feature...
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Trimethylamine N-oxide generation process was influenced by the proportion and source of macronutrients in the diet
March 2024
Trimethylamine N-oxide (TMAO) is a risk factor of various chronic diseases, which was produced by metabolism from precursors to trimethylamine (TMA) in gut and the oxidation from TMA in liver. The TMA...
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Structure, bioavailability and physicochemical properties of icariin-soymilk nanoparticle
March 2024
Soymilk is a natural nanocarrier. However, the performance of flavonoid-soymilk nano-complex remains unclear. In this work, icariin-soymilk nano-complexes (ISNCs) were successfully fabricated and characterized....
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Environmental enrichment in combination with Bifidobacterium breve HNXY26M4 intervention amplifies neuroprotective benefits in a mouse model of Alzheimer’s disease by modulating glutamine metabolism of the gut microbiome
March 2024
The gut microbiota-brain axis has emerged as a novel target for Alzheimer’s disease (AD), a neurodegenerative disease characterised by behavioural and cognitive impairment. However, most previous microbiome-based...
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Epicatechin attenuates lead (Pb)-induced cognitive impairment in mice: regulation on Nrf2 signaling pathway, and interference on the interaction between Pb with albumin
March 2024
Epicatechin (EC) was used in this study to antagonize the cognitive dysfunction caused by lead (Pb) exposure in mice. Eight-week-old male Kunming mice were treated with PbCl2 (20 mg/kg) and/or EC (50...
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The human-derived novel gut commensal Luoshenia tenuis regulates body weight and food intake in mice
March 2024
Many studies have revealed that gut microbes modulate host metabolism. In this study, we characterized the therapeutic effects of a novel gut commensal Luoshenia tenuis against host metabolic disorders....
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Transcriptomics integrated with metabolomics reveals the mechanism of CaCl2-HCl electrolyzed water-induced glucosinolate biosynthesis in broccoli sprouts
March 2024
Glucosinolates are important phytochemicals in Brassicaceae. We investigated the effect of CaCl2-HCl electrolyzed water (CHEW) on glucosinolates biosynthesis in broccoli sprouts. The results showed...
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Characterization of blueberry exosome-like nanoparticles and miRNAs with potential cross-kingdom human gene targets
March 2024
Edible plant derived exosome-like nanoparticles (ELNs) have been shown to have multiple nutraceutical functions. However, the diversity of plant materials makes the plant derived ELN study challenging....
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Biochemistry and transcriptome analysis reveal condensed tannins alleviate liver injury induced by regulating cholesterol metabolism pathway
March 2024
Free cholesterol has been considered to be a critical risk factor of nonalcoholic fatty liver disease (NAFLD). It remains unknown whether dietary intake of condensed tannins (CTs) have distinguishable...
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Mobile genetic elements facilitate the transmission of antibiotic resistance genes in multidrug-resistant Enterobacteriaceae from duck farms
March 2024
Multidrug-resistant (MDR) Enterobacteriaceae critically threaten duck farming and public health. The phenotypes, genotypes, and associated mobile genetic elements (MGEs) of MDR Enterobacteriaceae isolated...
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Demonstration of safety characteristics and effects on gut microbiota of Lactobacillus gasseri HMV18
March 2024
Human normal flora is a source of probiotics. The safety characteristics of a specific isolate determine its application in foods or drugs. The food-borne-pathogen antagonist strain Lactobacillus gasseri...
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Evaluation of the intracellular lipid-lowering effect of polyphenols extract from highland barley in HepG2 cells
January 2024
Active ingredients from highland barley have received considerable attention as natural products for developing treatments and dietary supplements against obesity. In practical application, the research...
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