Comparing frequentist and Bayesian methods to identify drivers of pathogen strain invasion: A temporal case study of pertussis in the United States
June 2026
Since the 20th century, it has been widely recognized that the emergence of new pathogens is closely linked to human activities such as global travel and environmental exploitation. In addition, the...
FluAttn: Antigenicity prediction of influenza A/H3N2 through attention-based feature mining
June 2026
The rapid antigenic drift of influenza A/H3N2 compromises the durability of vaccine-induced protection, underscoring the need for accurate antigenic assessment to evaluate vaccine efficacy and guide...
Dynamics and forecasting of an age-structured stochastic SIR model with Lévy perturbations via physics-informed neural networks
June 2026
Understanding and predicting real-world epidemic dynamics has consistently posed a formidable challenge. This study addresses an age-structured stochastic SIR model incorporating a general incidence...
Stochastic dynamics of Chikungunya virus infection model incorporating general incidence rate and immune responses
June 2026
This study investigates a stochastic model of Chikungunya virus (CHIKV) infection that incorporates a general incidence rate along with B-cell and CTL immune responses. Stochasticity is modeled through...
Dynamical analysis of the SVEIR-M epidemic model with age structure under media coverage
June 2026
With the frequent emergence and spread of new infectious diseases, poses severe threats to public health, and the government often relies on non-pharmaceutical interventions to cope. Meanwhile, the...
Impact of age-structured migration on malaria burden: A modelling-empirical analysis in sub-Saharan Africa
June 2026
Malaria transmission in Sub-Saharan Africa is strongly influenced by seasonal climatic variations and human mobility, particularly occupation-driven rural-to-urban migration. These dynamics contribute...
Dynamic analysis of syphilis model with the saturated incidence and early latent stage
June 2026
Syphilis is a blood-borne disease with multiple hidden-transmission stages caused by Treponema pallidum, and most infected individuals are asymptomatic as reported by the World Health Organization....
Modeling the seasonal and climate-dependent dynamics of visceral leishmaniasis in Brazil: Implications for transmission and Control
June 2026
Visceral leishmaniasis (VL) is a parasitic, zoonotic neglected tropical disease that remains a persistent public health challenge in endemic regions of Brazil, including the state of Maranhão. Transmission...
Age-structured next generation matrix and R0 calculation for Mycobacterium avium subsp. paratuberculosis (MAP)
June 2026
Paratuberculosis (Johne's disease), caused by Mycobacterium avium subspecies paratuberculosis (MAP), is known for its age-specific susceptibility, lifelong infection, varied shedding patterns, low diagnostic...
Urbanization influences hemorrhagic fever with renal syndrome transmission: 34-year evidence from China's national surveillance
June 2026
Mainland China accounts for over 90 % of the global hemorrhagic fever with renal syndrome (HFRS) cases, yet quantitative relationships between climate, urbanization and transmission dynamics remain...
Spatio-temporal forecasting of dengue in the Americas through hybrid mechanistic and data-driven models: Systematic review and meta-analysis
June 2026
This systematic review and meta-analysis (PROSPERO: CRD420251130769) synthesises 30 dengue modelling studies conducted in the Americas between 2016 and 2025, evaluating the integration of mechanistic...
Integrating Kolmogorov-Arnold networks with ordinary differential equations for efficient, interpretable, and robust deep learning: Epidemiology of infectious diseases as a case study
June 2026
This study extends universal differential equation (UDE) frameworks by integrating the Kolmogorov-Arnold Network (KAN) with ordinary differential equations, referred to as KAN-UDE, to achieve efficient...
Study on the resurgence of pertussis based on a stage-structured dynamic model
June 2026
Although pertussis vaccination has effectively reduced the global incidence rate and mortality, pertussis resurgence has been observed in many countries in recent years. This study aims to untangle...
Modeling and control of Chikungunya with chronic infection
June 2026
Recognized globally as a major public health concern in the tropics and subtropics, Chikungunya fever also poses a potential epidemic risk in areas of China such as Guangdong Province, where suitable...
Warming temperatures reduce lifespan and vectorial capacity of Anopheles mosquitoes in Ghana
June 2026
Climate change and variability are altering the ecology of malaria vectors, with implications for disease transmission in sub-Saharan Africa. In this study, we analysed long-term historical temperature,...
Absolute humidity drives seasonal influenza A transmission in Hong Kong through social contact modulation: Evidence from compartmental modeling
June 2026
Prior studies propose a U-shaped humidity-influenza relationship, yet the interplay between humidity-driven contact behaviors and transmission dynamics remains unclear....
Modeling the transmission dynamics and control strategies during the 2017 diphtheria outbreak in Jakarta, Indonesia
March 2026
Diphtheria has resurged globally, including in Indonesia, despite widespread vaccination since the 1970s. Knowledge gaps persist in understanding contemporary transmission drivers and effective outbreak...
Quantifying mpox transmission and control: A regional analysis of vaccination strategies in East Africa
March 2026
Africa is home to the endemic mpox disease, especially in the tropical rain-forest regions of Central and West Africa. Although it is mostly found in the Democratic Republic of the Congo, reports of...
Comparing virus incubation time in SIRC models: Deterministic versus stochastic approaches
March 2026
Time delays are a fundamental feature in modeling stochastic epidemic systems, as they capture the incubation period and other physiological lags inherent in disease transmission. In this work, we investigate...
Modelling, analysis and optimal control of Zika virus transmission dynamics based on sterile insect technique
March 2026
The sterile insect technique (SIT) has emerged as a promising tool for suppressing mosquito-borne diseases. This study develops a Zika virus transmission model integrating SIT, emphasizing both mosquito-borne...
Impact of high-order time-delayed information on epidemic propagation in multiplex networks
March 2026
Traditional epidemic models often overlook disease incubation periods and high-order social interactions, limiting their ability to capture real-world transmission dynamics. To address these gaps, we...
Novel approach to extract epidemiological information from waves in epidemic's profiles
March 2026
In this paper, we develop a novel mathematical framework based on the Kermack- McKendrick model to extract epidemiological parameters from real temporal profiles consisting of waves. The approach's...
A framework using large time series model for early warning of infectious diseases
March 2026
Infectious diseases controlling system is indispensable for weaken the damage to the people's life and property security caused by infectious diseases. An effective infectious diseases controlling system...
Dynamics and optimal control for tuberculosis transmission via a data-validated periodic model
March 2026
China is the third-largest contributor to the global incidence of tuberculosis (TB), and there are significant differences in the prevalence of TB among different age groups. Therefore, it is necessary...
Application of the type and target reproduction numbers to the evaluation of the influence of each prefecture in Japan on the disease spread
March 2026
In this study, by applying population mobility data in July, August and September of 2019–2023 in Japan to a multigroup epidemic model, we calculate the type and target reproduction numbers of each...
