Addressing poxvirus challenges in the Middle East to enhance biosafety and biosecurity measures
September 2024
The emergence and zoonotic transmission of poxviruses in the Middle East have been recognized as complex public health issues. Poxviruses, a vast family of DNA viruses, can infect many hosts, including...
A mathematical model for a disease outbreak considering waning-immunity class with nonlinear incidence and recovery rates
September 2024
In the spread of infectious diseases, intervention levels play a crucial role in shaping interactions between healthy and infected individuals, leading to a nonlinear transmission process. Additionally,...
Structure-based discovery of F. religiosa phytochemicals as potential inhibitors against Monkeypox (mpox) viral protein
September 2024
•The interaction of the A42R profilin-like protein with six phytochemicals found in an medicinal plant Ficus religiosa was studied.•Protein-ligand binding energies, IC50 values, ADMET characteristics,...
Exploring the Interplay Between Social Awareness and the Use of Bed Nets in a Malaria Control Program
September 2024
This research aims to understand the effect of human awareness and the use of bed nets on malaria control programs. A deterministic host-vector mathematical model was utilized and simplified using the...
Computational modeling and inhibition of SARS-COV-2 Papain-like protease enzyme: A potential therapeutic approach for COVID-19
September 2024
This study aims to investigate the potential impact of inhibitors targeting the papain-like protease (PLpro) of SARS-CoV-2 on viral replication and the host immune response. A mathematical model was...
Dynamic evolution of an SVEIR model with variants and non-pharmaceutical interventions for controlling COVID-19
June 2024
The epidemiological characteristics and distributions of two epidemics in Fujian Province of Southeast China were attributed to the complex interactions among variant, host, and non-pharmaceutical interventions...
Kalman filter based on a fractional discrete-time stochastic augmented CoVid-19 model
June 2024
In this paper, we study the dynamics of the CoVid-19 outbreak in Semarang, Indonesia, using a fractional CoVid-19 model. We first determine the effects of the isolation rate ∊ and infection rate β on...
Regulation of toxins and bioregulators under the Chemical Weapons Convention and the Biological and Toxin Weapons Convention
June 2024
In this paper we highlight how the apparent double coverage of toxins and bioregulators by both the Biological and Toxin Weapons Convention (BTWC) and the Chemical Weapons Convention (CWC) in fact masks...
Chi-square automatic interaction detection (CHAID) analysis of the use of safety goggles and face masks as personal protective equipment (PPE) to protect against occupational biohazards
June 2024
This study represents the first Spanish investigation to rigorously evaluate compliance with the use of safety goggles and face masks as essential personal protective equipment (PPE) in companies with...
Analyzing co-infection dynamics: A mathematical approach using fractional order modeling and Laplace-Adomian decomposition
June 2024
The co-infection of HIV and COVID-19 is a pressing health concern, carrying substantial potential consequences. This study focuses on the vital task of comprehending the dynamics of HIV-COVID-19 co-infection,...
Stability analysis of a fractional-order monkeypox epidemic model with quarantine and hospitalization
March 2024
The monkeypox epidemic has become a global health issue due to its rapid transmission involving nonhuman-to-human transmission in nonendemic areas. Various actions, such as quarantine, vaccination,...
Legal framework for the sharing of pathogens: Issues and recommendations
March 2024
The sharing of pathogens is of great significance for the continuous and comprehensive testing and monitoring of viral samples, vaccine and drug development, and the study of drug resistance and mutability...
Emerging bedaquiline resistance: A threat to the global fight against drug-resistant tuberculosis
March 2024
Bedaquiline resistance is increasingly observed in the treatment of rifampicin-resistant tuberculosis (TB), yet standardized regimens for managing bedaquiline-resistant TB are lacking. Studies indicate...
Mosquito-borne diseases: Assessing risk and strategies to control their spread in the Middle East
March 2024
Mosquito-borne diseases (MBDs), like malaria and mosquito-borne viruses (MBVs), have caused the deaths of millions of people. Their threat resides in the variety of transmission modes that they possess,...
Effectiveness of chemical inactivation of infectious liquid biological waste: A randomized sample study of research laboratories in Switzerland
March 2024
Laboratory wastewater has been suggested as an important escape route for microorganisms from research environments. Likely reasons for the unintentional release of laboratory organisms are shortcomings...
Development and assessment of cutting-edge biotechnologies
March 2024
The emergence of advanced biotechnologies has intensified in recent years. The rapid development of these biotechnologies has had a wide and profound impact globally, with the majority on the frontier...
Recurrent West Nile virus outbreak in the United States in 2022: Current challenges and recommendations
December 2023
West Nile virus (WNV) has afflicted various countries around the world, affecting not only humans but also non-human animals, such as horses and birds. WNV is an arbovirus that is transmitted to humans...
Biosafety management in high-biosafety-risk workshops for vaccine production in China
December 2023
This paper examines biosafety management in high-biosafety-risk workshops for vaccine production in China, focusing on the context of SARS-CoV-2 inactivated vaccine production. It addresses various...
Epidemiological modeling of Influenza-Like Illness (ILI) transmission in Jakarta, Indonesia through cumulative generating operator on SLIR model
December 2023
Influenza-Like Illness (ILI) constitutes a significant global health concern characterized by its high infection rates and widespread distribution worldwide. While influenza viruses, primarily types...
