Computational modeling and inhibition of SARS-COV-2 Papain-like protease enzyme: A potential therapeutic approach for COVID-19
September 2024
This study aims to investigate the potential impact of inhibitors targeting the papain-like protease (PLpro) of SARS-CoV-2 on viral replication and the host immune response. A mathematical model was...
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Dynamic evolution of an SVEIR model with variants and non-pharmaceutical interventions for controlling COVID-19
June 2024
The epidemiological characteristics and distributions of two epidemics in Fujian Province of Southeast China were attributed to the complex interactions among variant, host, and non-pharmaceutical interventions...
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Kalman filter based on a fractional discrete-time stochastic augmented CoVid-19 model
June 2024
In this paper, we study the dynamics of the CoVid-19 outbreak in Semarang, Indonesia, using a fractional CoVid-19 model. We first determine the effects of the isolation rate ∊ and infection rate β on...
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Regulation of toxins and bioregulators under the Chemical Weapons Convention and the Biological and Toxin Weapons Convention
June 2024
In this paper we highlight how the apparent double coverage of toxins and bioregulators by both the Biological and Toxin Weapons Convention (BTWC) and the Chemical Weapons Convention (CWC) in fact masks...
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Chi-square automatic interaction detection (CHAID) analysis of the use of safety goggles and face masks as personal protective equipment (PPE) to protect against occupational biohazards
June 2024
This study represents the first Spanish investigation to rigorously evaluate compliance with the use of safety goggles and face masks as essential personal protective equipment (PPE) in companies with...
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Analyzing co-infection dynamics: A mathematical approach using fractional order modeling and Laplace-Adomian decomposition
June 2024
The co-infection of HIV and COVID-19 is a pressing health concern, carrying substantial potential consequences. This study focuses on the vital task of comprehending the dynamics of HIV-COVID-19 co-infection,...
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Stability analysis of a fractional-order monkeypox epidemic model with quarantine and hospitalization
March 2024
The monkeypox epidemic has become a global health issue due to its rapid transmission involving nonhuman-to-human transmission in nonendemic areas. Various actions, such as quarantine, vaccination,...
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Legal framework for the sharing of pathogens: Issues and recommendations
March 2024
The sharing of pathogens is of great significance for the continuous and comprehensive testing and monitoring of viral samples, vaccine and drug development, and the study of drug resistance and mutability...
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Emerging bedaquiline resistance: A threat to the global fight against drug-resistant tuberculosis
March 2024
Bedaquiline resistance is increasingly observed in the treatment of rifampicin-resistant tuberculosis (TB), yet standardized regimens for managing bedaquiline-resistant TB are lacking. Studies indicate...
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Mosquito-borne diseases: Assessing risk and strategies to control their spread in the Middle East
March 2024
Mosquito-borne diseases (MBDs), like malaria and mosquito-borne viruses (MBVs), have caused the deaths of millions of people. Their threat resides in the variety of transmission modes that they possess,...
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Effectiveness of chemical inactivation of infectious liquid biological waste: A randomized sample study of research laboratories in Switzerland
March 2024
Laboratory wastewater has been suggested as an important escape route for microorganisms from research environments. Likely reasons for the unintentional release of laboratory organisms are shortcomings...
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Development and assessment of cutting-edge biotechnologies
March 2024
The emergence of advanced biotechnologies has intensified in recent years. The rapid development of these biotechnologies has had a wide and profound impact globally, with the majority on the frontier...
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Recurrent West Nile virus outbreak in the United States in 2022: Current challenges and recommendations
December 2023
West Nile virus (WNV) has afflicted various countries around the world, affecting not only humans but also non-human animals, such as horses and birds. WNV is an arbovirus that is transmitted to humans...
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Biosafety management in high-biosafety-risk workshops for vaccine production in China
December 2023
This paper examines biosafety management in high-biosafety-risk workshops for vaccine production in China, focusing on the context of SARS-CoV-2 inactivated vaccine production. It addresses various...
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Epidemiological modeling of Influenza-Like Illness (ILI) transmission in Jakarta, Indonesia through cumulative generating operator on SLIR model
December 2023
Influenza-Like Illness (ILI) constitutes a significant global health concern characterized by its high infection rates and widespread distribution worldwide. While influenza viruses, primarily types...
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Dual-use oversight: Is the scientific community fit for Purpose? What should be done if it is not?
December 2023
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Review of livestock biosecurity resources and trainings: Local, state, federal, and international organizations
December 2023
This study evaluates the accessibility and availability of publicly accessible biosecurity resources in the Fall of 2021, as part of the IN-PREPared and Gearing Up for Safety program. The research into...
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The 2023 International Workshop on Biosafety Laboratory Management and Techniques was held in Wuhan, China
December 2023
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Physico-chemical quality of ashes post-incineration and waste from laboratory automaton biochemistry, hematology and serology in Togo
September 2023
Biochemistry, hematology and serology laboratories produce very heterogeneous discharges capable of polluting water, soil and the environment. The aim of this study is to evaluate the physico-chemical...
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Allelic and genotypic analysis of the ACE I/D polymorphism for the possible prediction of COVID-19-related mortality and morbidity in Jordanian Arabs
September 2023
The coronavirus disease 2019 (COVID-19) pandemic has rapidly spread worldwide, posing a global medical concern. This novel RNA virus enters cells by binding to angiotensin-converting enzyme II (ACE2)...
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