Efficacy analysis of Salmeterol Xinafoate and Fluticasone Propionate power for inhalation in treating pediatric asthma patients
Available online 28 April 2025
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Glucosamine hinders IL-1β-induced CHON-001 cell injury and inflammation by inhibiting YY1-mediated TLR8
Available online 23 April 2025
Knee osteoarthritis (KOA) is threatening the health of humans. The glucosamine (GLC) has the potential to treat moderate osteoarthritis, and toll-like receptor (TLR) plays an important role in cartilage...
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Drug designing and synthesis of novel diphenyl 1,3,4 oxadiazoles: Multi-targeted therapeutics for the treatment of malassezia-induced dandruff
Available online 22 April 2025
This article explores the potential of novel Diphenyl 1,3,4-oxadiazole as an anti-dandruff agent against Malassezia species. Mono-, di-, and triglycerides generated from human skin sebum are broken...
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Exploring the mechanism of action of tolvaptan in the treatment of cor pulmonale pulmonary hypertension using network pharmacology and animal-based experiments
Available online 21 April 2025
Cor pulmonale is a heart disease caused primarily by pulmonary hypertension (PH) due to vascular lesions of the broncho-pulmonary tissue or pulmonary arteries. PH is a central link and prerequisite...
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Mechanism of Yangxuetongmai Decoction in treating essential hypotension: A network pharmacology, Mendelian randomization and molecular docking strategy analysis
Available online 21 April 2025
To investigate the mechanisms of Yangxuetongmai Decoction in treating essential hypotension using network pharmacology, Mendelian randomization, and molecular docking strategy analysis....
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Simulation, 3D-QSAR, molecular docking and pharmacophore mapping studies on indole derivatives as aromatase inhibitors
Available online 21 April 2025
Aromatase inhibition is a proven strategy for the treatment of ER+ breast cancer, which accounts for more than 70 % of cases of breast cancer. Indole-based aromatase inhibitors have changed the dynamics...
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Exploration of the mechanism of quercetin against GDM based on network pharmacology and molecular docking
Available online 21 April 2025
Gestational diabetes mellitus (GDM) is among the most common complications in pregnancy, endangering both the mother and the fetus. Quercetin demonstrated anti-hyperglycemic effects. Our research aimed...
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Chromium chelated carrageenan: An investigation of physicochemical properties, toxicity, and antimicrobial potential through a computational and experimental approach
Available online 21 April 2025
Carrageenan (car-) was extracted from Eucheuma isoforme and chelated with chromium ions (Cr³⁺) to evaluate its physicochemical properties, antimicrobial potential, and toxicity through both experimental...
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