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ISSN: 2772-5669

Tumor targeted and GSH stimuli-response α‑lactalbumin nanotubes co-delivering doxorubicin and siRNA for cancer therapy

•tLyp-1 promoted the cellular uptake of nanocarrier and cell apoptosis.•tLyp-1/NTs/Dox/siRNA have the potential use as nanocarrier for•tumor-targeted delivery.•tLyp-1/NTs/Dox/siRNA vastly curbed tumor...

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Bioactive compounds, nutraceutical values and its application in food product development of oyster mushroom

•Oyster mushroom has an excellent sources of biological proteins, fiber, vitamins (C, B1, B3, folic acid, B12), minerals (potassium & phosphorus), significant content of linoleic and oleic acid.•Due...

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Emerging applications of nanofibers electrospun from carbohydrate polymers

•Electrospun nanofibers presenting a wide variety of applications•Carbohydrate polymers having advantages related to its biocompatible nature•Tissue engineering, biomedical, textile, and environmental...

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SERS-tag technology in food safety and detection: sensing from the “fingerprint” region to the “biological-silent” region

•An overview of the most recent applications of the SERS-tags technology for food safety determination.•Few reviews are published on the transition of SERS-tags from the “fingerprint” region and the...

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Physico-chemical properties of wild edible fruit Meyna laxiflora Robyns (Alu): production of Alu fruit powder by using drying aid

•Physicochemical properties of underutilized fresh fruit, pulp and powder. MD was used as drying carrier to develop Alu powder.•Preliminary phytochemicals, % of solubility and % of particle size distribution...

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Mechanism of microbial spore inactivation through electromagnetic radiations: a review

•Electromagnetic radiations have the potential to be used commercially for the inactivation of spores in the food industry.•The structure of spores and its different components shielding genomic material...

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Different characteristics of 40 kinds of free amino acids and 5-amino levulinic acid between wines and sakes (Japanese rice wines)

The importance of this manuscript is as follows: The purpose of this study was to elucidate 40 kinds of FAA profiles in wines and sakes. In addition, the present study also provided the contents of...

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Dynamics and functionalities of bacterial community during foxtail millet dough fermentation by metagenomic analysis

•Heterofermentative lactic acid bacteria were dominant in foxtail millet dough.•Limosilactobacillus_fermentum increased markedly after fermentation.•Companilactobacillus_crustorum was notably found...

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Evaluation and salivary biochemistry associations of sour-salty taste interaction

•A quantitative method to assess the magnitude of taste interaction is established.•Lower sour taste intensity enhances salty taste perception.•Increasing higher sour taste intensity gradually suppresses...

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Simultaneous detection of 22 mycotoxins in grape by QuEChERS and ultra-high-performance liquid chromatography coupled with quadrupole/orbitrap high-resolution mass spectrometry

•A UPLC-Q-Orbitrap HRMS method was developed to analyze 22 mycotoxins in grape.•The pretreatment procedure and UPLC-Q-Orbitrap HRMS conditions were investigated.•The method is reliable, accurate, and...

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A review of the interaction between diet composition and gut microbiota and its impact on associated disease

•This review describes the pathways of carbohydrate, protein, and fat metabolism, as well as their interconnections and regulatory mechanisms, as well as how this information may be utilized to maintain...

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A review: the mechanism of plant-derived polysaccharides on osteoblasts and osteoclasts

•The transcription factors and signaling pathways involved in the role of osteoblasts and osteoclasts in osteoporosis are summarized.•A variety of edible plant-derived ingredients with anti-osteoporosis...

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Antioxidant and anti-HepG2 cell activities of a novel bioactive peptide from cowhide collagen in vitro

•BPCC have significant free radical scavenging and biological macromolecule protection ability.•BPCC inhibited the viability of HepG2 cells in does dependent manner and induced apoptosis mediated cell...

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Progress in the preparation, identification and biological activity of walnut peptides

•The advantages, disadvantages and development trend of the method to obtain defatted walnut powder by pretreatment of walnuts are systematically described.•The preparation process as well as the isolation...

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Chemical constituents and anticoagulant activity from Delphinium brunonianum Royle

•Compounds 2-4 were isolated from Delphinium brunonianum Royle for the first time and compounds 5, 7-10, 12, 14, 15-16 were isolated from Delphinium for the first time.•Compounds 10, 14 and 15 had good...

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Influences of Lactiplantibacillus plantarum and Saccharomyces cerevisiae fermentation on the nutritional components, flavor property and lipid-lowering effect of highland barley

•Either L. plantarum or S. cerevisiae fermentation could change the contents of the main components of highland barley.•The profile of volatile substances of S. cerevisiae fermentation was far different...

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Protective effects and microarray-based mechanism of sea cucumber hydrolysates against high-glucose induced nephrotoxicity in mouse glomerulus mesangial cells

•Compared the inhibitory effects of the AP and SP hydrolysates cellular growth of GMCs.•Clarified the mechanism of protective effects via microarray.•AP and SP hydrolysates promoted the apoptosis via...

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Identification of novel targets and mechanisms of wogonin on lung cancer, bladder cancer, and colon cancer

•WOG suppresses cancers via regulating arachidonic acid, Ras, MAPK, linoleic acid, PI3K-Akt, folate biosynthesis pathways.•WOG inhibits the proliferation of A549 cells through regulating 18 targets,...

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Tetramethylpyrazine and paeoniflorin combination (TMP-PF) inhibits angiogenesis in atherosclerosis via miR-126/VEGF/VEGFR2 signaling pathway

•Ox-LDL promoted angiogenesisby downregulating miR-126 expression, and increased the expression of VEGF, VEGFR2, bFGF, and FGFR1 in ox-LDL-induced HUVECs.•TMP-PF inhibited angiogenesisby upregulating...

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Classification and antioxidant assays of polyphenols: a review

•The antioxidant capacity of polyphenols could be affected by their structure, stability, bioavailability and food matrix.•The chemical antioxidant assays are simple and fast, but these reactions vary...

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Industrialization progress and challenges of cultivated meat

•The present research status and difficulties of cultivated meat were summarized.•The advantages and disadvantages of cultivated meat are discussed objectively.•The requirements for the cultivated meat...

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Isolation of exogenous fungi from Notoginseng Radix et Rhizoma and preliminary analysis of toxigenic fungi

•To understand the status of contamination of some domestic Notoginseng Radix et Rhizoma in China.•To provide guidance for the rational processing and scientific storage of Notoginseng Radix et Rhi...

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Effect of high temperature short time infrared roasting of peanuts

•The best treatment for infrared roasting of peanuts was 13.72% MC with 1 rpm, and it significantly enhances the quality of peanuts•Minimal changes for total phenolic content were found and varied from...

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Effects of coating formulation on structural changes of turkey nugget during frying: MRI evaluation

•MRI method was employed to study the effects of coating type on structure of turkey nugget during frying.•Fractal dimension was applied as an indicator to investigate the extension of the surface roughness...

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Colorimetric indicator based on zwitterionic anti-freezing hydrogel and alizarin for visual monitoring of salmon fillets freshness

•Zwitterionic hydrogels with good anti-freezing property was developed.•Incorporation of alizarin endowed the hydrogel with pH-sensitive property.•Freshness indication of salmon at subzero conditions...

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