Human breast milk stem cells: characteristics, functions, and future applications
March 2027
•hBSCs have advanced breast milk research over the last decade•hBSCs could regulate lactation, promote infant and child growth and development•hBSCs could promote disease treatment and cellular milk...
Establishment of innovative preparation technology for multi-targeted extracts of mulberry leaves and insight into inhibition mechanism of α-glucosidase: in vitro digestion, kinetics, and spectroscopic analysis
March 2027
•AMLE was prepared by combining AB-8 macroporous resin and 001 × 7 cationic resin to enrich flavonoids and DNJ.•AMLE exhibited better hypoglycemic activity by inhibiting α-glucosidase compared to commercial...
Enhancing urolithin A yield by Limosilactobacillus fermentum FUA033 in human gut microbiota across three urolithin-metabotype mice
March 2027
•Different urolithin metabotypes (UMs) were successfully developed in mice.•L. fermentum FUA033 significantly enhanced Uro-A production in UMs mice.•L. fermentum FUA033 modified gut microbiota composition...
Structural and in vitro fecal fermentation characteristics of oligosaccharides produced from Chinese quince seed gum by H2O2
March 2027
1.Chinese quince seed gum is sustainable resource of oligosaccharides (OCGs)2.OCGs are potentially strong water-absorbing, semi-solid food ingredients3.The antioxidant and in vitro fermentation properties...
Houttuynia cordata traditional extract regulates uric acid transporter and reduces xanthine oxidase activity in hyperuricemic mice
March 2027
•H. cordata extracts significantly reduce uric acid levels in both in vitro and in vivo models, inhibiting uric acid absorption and overproduction in hyperuricemia.•H. cordata inhibits xanthine oxidase...
Nanoencapsulation of thyme oleoresin: a novel strategy to enhance bioactive ingredients' bioaccessibility in functional ultrafiltration-labneh and prolong shelf life
March 2027
1.Preparation of thyme oleoresin by green techniques supercritical fluid CO2 (SCCO2) and comprehensive characterization of phytochemical composition of ThOR.2.Polymerized whey protein was used to encapsulate...
Gut-joint axis mediates susceptibility to osteoarthritis in female adult offspring rats with prenatal caffeine exposure
March 2027
•PCE female adult offspring rats were susceptible to osteoarthritis•PCE changed gut microbiota and decreased butyric acid in female adult offspring rats•Increased inflammatory mediated imbalanced cartilage...
Genetic diversity and functional insights of nattokinase variants in Bacillus
January 2027
•Bacillus spp. harbor extensive NK variants, with 89.58% of strains containing NK genes.•A novel strategy is proposed for isolating high fibrinolytic Bacillus strains based on the correlation between...
Revealing the phenolic profile, antioxidant, and antidiabetic properties of enzymatically hydrolyzed seriguela: a strategic approach to enhance the value of an exotic fruit
January 2027
•Enzymatic hydrolysis significantly increased the antioxidant and antidiabetic properties of seriguela pulp.•The content of the bioactive compounds increased up to 3-fold after hydrolysis.•The HPLC...
Mulberry leaf polysaccharide enhances cyclophosphamide-induced immune response in mice via MAPK/NF-κB pathway and gut microbiota regulation
January 2027
•MLP can enhance the immune response in immunosuppressed mice.•MLP regulates the immune response in mice by activating the MAPK and NF-kB pathways.•MLP can enhance the immune function of mice by increasing...
Integrated network pharmacology and gut microbiota analysis to reveal the immunomodulatory mechanisms of Lonicerae japonicae Flos polysaccharides
January 2027
•Lonicerae Japonicae Flos polysaccharides(LJFP) alleviates immunosuppression induced by cyclophosphamide(CTX) in mice.•LJFP regulates intestinal flora disorders in immunosuppressed mice induced by CTX.•LJFP...
Dihydromyricetin microcapsule preparation and effect on renal function and gastric mucosa in type 2 diabetic mice
January 2027
•MicroDMY increased DMY's oral bioavailability by 85.79%, addressing DMY's poor solubility and absorption issues.•MicroDMY significantly improved glucose and lipid levels in type 2 diabetic mice, demonstrating...
Preparation and characterization of polypeptide film/coating derived from Idesia polycarpa Maxim. Cake meal and its application in nectarine preservation
January 2027
•Preparation of novel fruit cling film/coating from a novel antioxidant peptide CIP.•The films have excellent oxidation resistance, mechanical properties and thermal stability.•The coating/3% fraction...
Discovery of novel key non-volatile metabolites linked to Lactiplantibacillus plantarum in pickled chili peppers fermentation: DL-p-hydroxyphenyllactic acid, 3-phenyllactic acid, catechol, and acetylcholine
January 2027
•Multi-omics, targeted analysis and inoculation validation verify results reliability.•The dominant microbes of pickled chili peppers were identified and screened.•The key non-volatile metabolites linked...
Multi-omics analysis reveals the anti-obesity and hepatoprotective properties of Termitomyces intermedius extracts
January 2027
•Termitomyces intermedius methanol extracts exhibit remarkable anti-obesity and hepatoprotective properties.•The intervention of methanolic extracts of Termitomyces intermedius leads to changes in serum...
Identification of exopolysaccharide produced by Bacillus amyloliquefaciens PFY02 and its potential biological activity and hypoglycemic function
January 2027
•A novel exopolysaccharide (EPS) was obtained from Bacillus amyloliquefaciens PFY02.•The EPS was a neutral heteropolysaccharide.•The EPS has α-1,2-Man, β-1-GlcA, β-1-Gal, α-1,4-Man, and β-1-Glc glycosidic...
Physicochemical properties, structural characteristics, and rheological behavior of mango peel pectin with different degrees of esterification
January 2027
•Purification reduced protein, ash, and impurities in mango peel pectin (MP).•De-esterified mango peel pectins (DEMPs) was prepared by alkaline method.•De-esterification enhanced solubility, water-holding...
Classification of strawberry maturity using Swin Transformer V2: integrating near-infrared spectral, chemical, and optical properties
January 2027
•Swin Transformer V2 achieves perfect accuracy in strawberry maturity assessment.•Novel multi-modal dataset combines visual, chemical, and spectral measurements.•Brix-to-acidity ratio effectively distinguishes...
Effects of sodium sulfonate with different alkyl chain lengths on starch in starch-rich system: structure, surface properties, and interaction mechanism
January 2027
•Sodium sulfonate with different chain lengths complex with starch in various forms.•Adjusting the chain length of emulsifier to promote the starch surface properties.•Electrostatic interaction induced...
Unlocking the potential of naringenin: a systematic review and meta-analysis of its impact on obesity-related disorders in mouse models
January 2027
•The first systematic review focusing on the anti-obesity effect of Naringenin in animal models.•Naringenin intervention significantly improved obesity-related indicators in mouse models of MetS, NAFLD,...
Effect of DJ-1-regulated PI3K/Akt signaling pathway on mitochondrial apoptosis during storage in Qinchuan beef
January 2027
•DJ-1 regulates apoptosis in Qinchuan beef cells through the PI3K/Akt pathway.•Compound-23, a DJ-1 stabilizer, can significantly increase the DJ-1 protein content in Qinchuan beef.•DJ-1 stabilizer decreased...
Transforming food consumer analysis: the role of machine learning in Food Consumer Demand 4.0
January 2027
•The conception of Food Consumer Demand 4.0 was introduced for the first time.•The recent advances in food consumer analysis combined with ML were reviewed.•The advantages and disadvantages of common...
Comprehensive evaluation of the application and prospects of spices in aquatic products: a review
January 2027
•Differences in the effects of spices are mainly due to differences in their characteristics, which include odor, volatiles, plant parts, potency and flavor.•Nutritional composition, storage properties,...
Biological effects of viable and nonviable Bacillus subtilis on the microbiota-gut-blood system through the modulation of gut microbiota and circulating metabolites
January 2027
•Tyrosine and tryptophan metabolism pathways participate in host immunity•Viable and nonviable Bacillus subtilis play distinct roles in the host intestinal system•Viable and nonviable B. subtilis modulate...
Biological functions, synthetic biology strategies, and application prospects of ganoderic acid in the food industry: a review
January 2027
•Function, biosynthetic pathway and application of synthetic biology in its production of ganoderic acid.•Possibility and potential research areas of ganoderic acid in future functional food research.•Potential...